产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| 1:100-1:1000 |
| 1:100-1:1000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS, 20% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1.32 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_2036328
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
BCL2 like 10 , BCL-B , Boo , Diva , bcl2-L-10
细胞定位
Mitochondrion , Nucleus membrane
功能与背景
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]
数据库
研究领域
產品图片
![Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872](/templates/default/js/lightbox/images/loading.gif "Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872")
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GTX111872 IHC-P Image
Immunohistochemical analysis of paraffin-embedded A549 Xenograft, using BCL2L10(GTX111872) antibody at 1:100 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX111872 ICC/IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using BCL2L10(GTX111872) antibody at 1:200 dilution.
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GTX111872 WB Image
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with BCL2L10 antibody [N2C2], Internal (GTX111872) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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文献引用
目前没有使用 BCL2L10 antibody [N2C2], Internal (GTX111872) 的文献被收录。快来回报我们第一篇参考文献吧！
产品评论
目前没有使用 BCL2L10 antibody [N2C2], Internal (GTX111872) 的产品评论被收录。快发表第一篇产品评论吧！
![Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872](/upload/website/prouct_img/small/GTX111872/GTX111872_IHC_w_23060500_521.webp "Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872")
![Anti-BCL2L10 antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX111872](/upload/website/prouct_img/small/GTX111872/GTX111872_IFA_w_23060500_240.webp "Anti-BCL2L10 antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX111872")
![Anti-BCL2L10 antibody [N2C2], Internal used in Western Blot (WB). GTX111872](/upload/website/prouct_img/small/GTX111872/GTX111872_42347_20220311_WB_w_23060500_123.webp "Anti-BCL2L10 antibody [N2C2], Internal used in Western Blot (WB). GTX111872")
![Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872](/upload/website/prouct_img/normal/GTX111872/GTX111872_IHC_w_23060500_521.webp "Anti-BCL2L10 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX111872")
![Anti-BCL2L10 antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX111872](/upload/website/prouct_img/normal/GTX111872/GTX111872_IFA_w_23060500_240.webp "Anti-BCL2L10 antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX111872")
![Anti-BCL2L10 antibody [N2C2], Internal used in Western Blot (WB). GTX111872](/upload/website/prouct_img/normal/GTX111872/GTX111872_42347_20220311_WB_w_23060500_123.webp "Anti-BCL2L10 antibody [N2C2], Internal used in Western Blot (WB). GTX111872")
