形式
Liquid
存储溶液
Tissue culture supernatant
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
免疫原种属
Human
免疫原
Prokaryotic recombinant protein corresponding to the internal domain of the protein of the human CD30 molecule.
纯化方式
Unpurified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
别名
TNF receptor superfamily member 8 , CD30 , D1S166E , Ki-1
功能与背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
数据库
研究领域