产品说明
摘要
Ki67 antibody recognizes Ki67 antigen, a nuclear nonhistone protein with a predicted molecular weight of 359 kDa. Ki67 is present during the active phases of the cell cycle and is used clinically as a proliferation marker. Ki67 antibody is used extensively in immunohistochemistry to assess the grade or apparent aggressiveness of various malignancies.
产品应用
应用说明
IHC-P: 1:100-1:1000. Staining of formalin-fixed tissues is required by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: 1/200. Predicted molecular weight: 359 kDa. Not tested in other applications
预期分子量
阳性对照
Tonsil
产品属性
形式
Liquid
存储溶液
Tissue culture supernatant, PBS, BSA
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
免疫原种属
Human
纯化方式
Tissue culture supernatant
偶联
Unconjugated
RRID
AB_422351
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
marker of proliferation Ki-67 , KIA , MIB- , MIB-1 , PPP1R105
细胞定位
Nucleus , Nucleolus
功能与背景
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
数据库
研究领域
產品图片
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus in human cervical metaplasia (left) and carcinoma (right) by immunohistochemical analysis. Sample: Paraffin-embedded human cervix. Ki67 antibody [SP6] (GTX16667) diluted at 1:200.
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human breast carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human colon cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human endometrial carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human ovarian cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human cervical carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human colon cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX16667 IHC-P Image
The data was published in the journal Front Oncol in 2020.PMID: 32426268
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GTX16667 IHC-P Image
The data was published in the journal Nat Commun in 2016.PMID: 27187615
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GTX16667 IHC-P Image
The data was published in the journal Nat Commun in 2016.PMID: 27187615
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GTX16667 IHC-P Image
The data was published in the journal BMC Cancer in 2019.PMID: 30606143
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GTX16667 IHC-P Image
The data was published in the journal Nat Commun in 2016.PMID: 27187615
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GTX16667 IHC Image
The data was published in the journal Nat Commun in 2016. PMID: 26965827
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GTX16667 IHC-P Image
The data was published in the journal PLoS One in 2015. PMID: 25747583
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GTX16667 IHC Image
The data was published in the journal Nat Commun in 2016. PMID: 26965827
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GTX16667 IHC Image
The data was published in the journal Nat Commun in 2016. PMID: 26965827
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GTX16667 IHC-P Image
The data was published in the 2021 in Fujita Med J. PMID: 35111543
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GTX16667 IHC-P Image
The data was published in the 2021 in Fujita Med J. PMID: 35111543
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GTX16667 IHC-P Image
The data was published in the journal Cell Death Dis in 2019. PMID: 31659152
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GTX16667 IHC-P Image
The data was published in the journal Cell Death Dis in 2019. PMID: 31659152
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GTX16667 IHC-P Image
The data was published in the journal Sci Rep in 2017. PMID: 28785010
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文献引用
产品评论
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