产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| Assay dependent |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
预测种属反应
Mouse, Rabbit, Sheep, Bovine, Pig, Chimpanzee, Rhesus Monkey(>80% identity)
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Androgen Receptor. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
RRID
AB_2909933
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
androgen receptor , AIS , AR8 , DHTR , HUMARA , HYSP1 , KD , NR3C4 , SBMA , SMAX1 , TFM
细胞定位
Nucleus,Cytoplasm
功能与背景
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
数据库
研究领域
產品图片
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/templates/default/js/lightbox/images/loading.gif "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
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GTX636021 IHC-P Image
Androgen Receptor antibody [HL1049] detects Androgen Receptor protein by immunohistochemical analysis.Sample: Paraffin-embedded rat tissues.Androgen Receptor stained by Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636021 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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GTX636021 IHC-P Image
Androgen Receptor antibody [HL1049] detects Androgen Receptor protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human prostate cancer.Androgen Receptor stained by Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636021 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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GTX636021 IHC-P Image
Androgen Receptor antibody [HL1049] detects Androgen Receptor protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human prostate cancer.Androgen Receptor stained by Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636021 ICC/IF Image
Androgen Receptor antibody [HL1049] detects Androgen Receptor protein at nucleus by immunofluorescent analysis.Sample: 22RV1 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: Androgen Receptor stained by Androgen Receptor antibody [HL1049] (GTX636021) diluted at 1:500.Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000.
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文献引用
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产品评论
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![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_44277_20221223_IHC-P_multiple_R_22122821_517.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_44277_20220408_WB_w_23061202_386.webp "Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_44277_20220318_IHC-P_1_w_23061202_296.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_44277_20210409_WB_w_23061202_660.webp "Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_44277_20220318_IHC-P_w_23061202_877.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636021](/upload/website/prouct_img/small/GTX636021/GTX636021_T-44228_20210416_ICC_IF_w_23061202_549.webp "Anti-Androgen Receptor antibody [HL1049] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_44277_20221223_IHC-P_multiple_R_22122821_517.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_44277_20220408_WB_w_23061202_386.webp "Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_44277_20220318_IHC-P_1_w_23061202_296.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_44277_20210409_WB_w_23061202_660.webp "Anti-Androgen Receptor antibody [HL1049] used in Western Blot (WB). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_44277_20220318_IHC-P_w_23061202_877.webp "Anti-Androgen Receptor antibody [HL1049] used in IHC (Paraffin sections) (IHC-P). GTX636021")
![Anti-Androgen Receptor antibody [HL1049] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636021](/upload/website/prouct_img/normal/GTX636021/GTX636021_T-44228_20210416_ICC_IF_w_23061202_549.webp "Anti-Androgen Receptor antibody [HL1049] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636021")
