GeneTex is committed to establishing the most extensive product line of recombinant monoclonal antibodies for human GPCRs. These antibodies will be thoroughly characterized through enhanced “Five Pillar” validation strategies that feature knockdown/knockout lysates, comparable antibodies, cell fractionation, detection of endogenous GPCR expression, and overexpression. In addition, specialized testing using human GPCR arrays will be utilized when feasible. The goal is to generate the most diverse, expansive, and meticulously verified antibody reagents for GPCR biology research.

 

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Explore Our GPCR Antibodies

 

 

Class A

 

Subclass

Target

5-hydroxytryptamine

 5-hydroxytryptamine Receptor 4 (HTR4)

5-hydroxytryptamine

 5-hydroxytryptamine Receptor 7 (HTR7)
5-hydroxytryptamine 5-hydroxytryptamine Receptor 1E (5-HT1E)

Acetylcholine

 Cholinergic Receptor Muscarinic 1 (mAChR M1)

Adenosine

 Adenosine A1 Receptor (ADORA1)

Adenosine

 Adenosine A2a Receptor (ADORA2A)
Adenosine

Adenosine A2b Receptor (ADORA2B)

Adrenoceptors

Alpha 1a Adrenergic Receptor (ADRA1A)

Adrenoceptors

 Alpha 1b Adrenergic Receptor (ADRA1B)
Adrenoceptors Alpha 1d Adrenergic Receptor (ADRA1D)
Adrenoceptors Alpha 2a Adrenergic Receptor (ADRA2A)

Adrenoceptors

 Alpha 2b Adrenergic Receptor (ADRA2B)
Adrenoceptors Beta 1 Adrenergic Receptor (ADRB1)

Adrenoceptors

Beta 2 Adrenergic Receptor (ADRB2)

Adrenoceptors

 Beta 3 Adrenergic Receptor (ADRB3)
Angiotensin Angiotensin II Receptor Type 1 (AGTR1)
Apelin Apelin Receptor (APLNR)
Cannabinoid Cannabinoid Receptor 2 (CNR2)
Chemokine C-C Motif Chemokine Receptor 1 (CCR1)
Chemokine C-C Motif Chemokine Receptor 2 (CCR2)
Chemokine C-C Motif Chemokine Receptor 4 (CCR4)
Chemokine C-C Motif Chemokine Receptor 5 (CCR5)
Chemokine C-C Motif Chemokine Receptor 7 (CCR7)
Chemokine C-C Motif Chemokine Receptor 9 (CCR9)
Chemokine C-C Motif Chemokine Receptor 10 (CCR10)
Chemokine Atypical Chemokine Receptor 4 (CCR11)
Chemokine C-X-C Motif Chemokine Receptor 1 (CXCR1)
Chemokine C-X-C Motif Chemokine Receptor 2 (CXCR2)
Chemokine C-X-C Motif Chemokine Receptor 3 (CXCR3)
Chemokine C-X-C Motif Chemokine Receptor 4 (CXCR4)
Chemokine C-X-C Motif Chemokine Receptor 5 (CXCR5)
Chemokine C-X-C Motif Chemokine Receptor 6 (CXCR6)
Chemokine Atypical Chemokine Receptor 3 (CXCR7)

Cholecystokinin

 Cholecystokinin B Receptor (CCKBR)

Chemokine

 C-X3-C Motif Chemokine Receptor 1 (CX3CR1)
Class A Orphans

G Protein-Coupled Receptor 15 (GPR15)
Class A Orphans

G Protein-Coupled Receptor 21 (GPR21)

Class A Orphans

 G Protein-Coupled Receptor 23 (GPR23)

Class A Orphans

G Protein-Coupled Receptor 31 (GPR31)

Class A Orphans

 G Protein-Coupled Receptor 45 (GPR45)
Class A Orphans

G Protein-Coupled Receptor 50 (GPR50)

Class A Orphans

 G Protein-Coupled Receptor 88 (GPR88)

Class A Orphans

 G Protein-Coupled Receptor 126 (GPR126)
Class A Orphans G Protein-Coupled Receptor 148 (GPR148)
Class A Orphans Leucine Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5)
Class A Orphans Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6)
Class A Orphans

MAS Related GPR Family Member F (MRGPRF)

Class A Orphans

 MAS related GPR family member X1 (MRGX1)
Complement Complement C3A Receptor 1 (C3AR1)

Complement

 Complement Component 5a Receptor 2 (C5L2)
Dopamine Dopamine Receptor D1 (DRD1)
Dopamine Dopamine Receptor D2 (DRD2)
Dopamine Dopamine Receptor D4 (DRD4)
Dopamine Dopamine Receptor D5 (DRD5)
Endothelin Endothelin Receptor Type B (Ednrb)

Estrogen

 G protein-coupled estrogen receptor 1 (GPR30)

Formylpeptide

Formyl Peptide Receptor 1 (FPR1)
Formylpeptide Formyl Peptide Receptor 2 (FPRL1)

Free fatty acid

Free Fatty Acid Receptor 1 (GPR40)
Free fatty acid Free Fatty Acid Receptor 2 (GPR43)
Free fatty acid Free Fatty Acid Receptor 4 (GPR120)

Ghrelin

 Growth Hormone Secretagogue Receptor (GHS-R1)

Hormones
(TSH, FSH, and GnRH)

 Follicle Stimulating Hormone Receptor (FSHR)

Hormones
(TSH, FSH, and GnRH)

Thyroid Stimulating Hormone Receptor (TSHR)

Hormones
(TSH, FSH, and GnRH)

 Gonadotropin Releasing Hormone Receptor (GnRHR)
Histamine Histamine Receptor H1 (HRH1)

Hydroxycarboxylic acid

 Hydroxycarboxylic Acid Receptor 1 (GPR81)

Kisspeptin

 KISS1 Receptor (GPR54)

Lysophospholipid

 Lysophosphatidic Acid Receptor 2 (EDG-4/LPAR2)
Lysophospholipid PAF Receptor (PTAFR)
Lysophospholipid Sphingosine-1-phosphate Receptor 2 (S1PR2)
Lysophospholipid Sphingosine-1-phosphate Receptor 5 (S1PR5)
Melanocortin Melanocortin 1 Receptor (MC1R)
Melanocortin Melanocortin 4 Receptor (MC4R)
Melanocortin Melanocortin 5 Receptor (MC5R)

Neuromedin U

Neuromedin U Receptor 2 (NMUR2)
Opioid Opioid Receptor Delta 1 (OPRD1)
Opioid Opioid Receptor Mu 1 (OPRM1)
Opioid

Opsin Blue (OPN1SW)
Opsins Opsin Red / Green (OPN1MW2)
Opsins Retinal G Protein Coupled Receptor (RGR)
Opsins Rhodopsin (RHO)
Prostanoid Prostaglandin E Receptor 3 (PTGER3)

Proteinase-activated receptor

F2R Like Trypsin Receptor 1 (PAR2)

Proteinase-activated receptor

 Coagulation Factor II Thrombin Receptor Like 2 (PAR3)

Relaxin family

 Relaxin Family Peptide Receptor 1 (LGR7)
P2Y Purinergic Receptor P2Y1 (P2Y1)
P2Y Purinergic Receptor P2Y2 (P2Y2)
P2Y Purinergic Receptor P2Y11 (P2Y11)
P2Y Purinergic Receptor P2Y12 (P2Y12)
Somatostatin Somatostatin Receptor 2 (SSTR2)
Somatostatin Somatostatin Receptor 3 (SSTR3)
Somatostatin Somatostatin Receptor 4 (SSTR4)
Somatostatin Somatostatin Receptor 5 (SSTR5)
Tachykinin Neurokinin 1 Receptor (NK1R)

 

 

 

Class B1

 

Subclass

Target

Calcitonin

 Calcitonin Receptor Like Receptor (CRLR)

Glucagon family

Glucagon Like Peptide 1 Receptor (GLP1R)

Parathyroid

Parathyroid Hormone 1 Receptor (PTH1R)

VIP and PACAP

 Vasoactive Intestinal Peptide Receptor 2 (VPAC2)

 

Class B2

Learn more about adhesion GPCRs

 

Subclass

Target

Adhesion

Adhesion G Protein-Coupled Receptor B1 (BAI1)

Adhesion

 Adhesion G Protein-Coupled Receptor B2 (BAI2)

Adhesion

 Adhesion G Protein-Coupled Receptor B3 (BAI3)

Adhesion

Adhesion G protein-Coupled Receptor E1 (F4/80)

Adhesion

Adhesion G Protein-Coupled Receptor E2 (EMR2)

Adhesion

Adhesion G Protein-Coupled Receptor E5 (CD97)

Adhesion

Cadherin EGF LAG Seven-Pass G-type Receptor 1 (CELSR1)

Adhesion

Cadherin EGF LAG Seven-Pass G-type Receptor 2 (CELSR2)

Adhesion

Adhesion G Protein-Coupled Receptor G3 (GPR97)
Adhesion Adhesion G Protein-Coupled Receptor G5 (GPR114)

Adhesion

 Adhesion G Protein-Coupled Receptor F5 (GPR116)

Adhesion

 Adhesion G protein-Coupled Receptor A1 (GPR123)
Adhesion

Adhesion G protein-Coupled Receptor G6 (GPR126)
Adhesion

Adhesion G protein-Coupled Receptor D1 (GPR133)
Adhesion Adhesion G protein-Coupled Receptor L1 (Latrophilin 1)
Adhesion

Adhesion G protein-Coupled Receptor L2 (Latrophilin 2)

Adhesion

  Cadherin EGF LAG Seven-Pass G-Type Receptor 2 (CELSR2)

 

Class C

 

Subclass

Target

Calcium-sensing

Calcium Sensing Receptor (CASR)
Class C Orphans G Protein-Coupled Receptor Class C Group 5 Member A (GPRC5A)

Class C Orphans

 G protein-Coupled Receptor Class C Group 5 Member C (GPRC5C)

Class C Orphans

 G protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)
GABA Gamma-aminobutyric Acid Type B Receptor Subunit 1 (GABBR1)

GABA

 Gamma-aminobutyric Acid Type B Receptor Subunit 2 (GABBR2)

Metabotropic glutamate

 Glutamate Metabotropic Receptor 1 (mGluR1)

Metabotropic glutamate

 Glutamate Metabotropic Receptor 4 (mGluR4)
Metabotropic
glutamate		 Glutamate Metabotropic Receptor 5 (mGluR5)

Metabotropic glutamate

 Glutamate Metabotropic Receptor 6 (mGluR6)

 

Class F

 

Subclass

Target

Frizzled

 Frizzled 1 (FZD1)

Frizzled

Frizzled 4 (FZD4)
Frizzled

Frizzled 8 (FZD8)
Frizzled

Frizzled 9 (FZD9)
Frizzled Smoothened Homolog (SMO)

 

 

Taste 2

 

Subclass

Target

Taste 2

Taste 1 Receptor Member 2 (TAS1R2)

Taste 2

Taste 2 Receptor Member 38 (TAS2R38)

 

 

Learn more about GPCRs

 

 

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