应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品说明
The Binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR
domains the third domain being critical as, cleavage of this domain at the major cleavage site
ASP-265 abrogates binding to the N-terminal fragment.
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Leucocytes harvested from the pleural cavity of patients with idiopathic spontaneous pneumothorax
纯化方式
Protein A purified
From tissue culture supernatant
偶联
Unconjugated
RRID
AB_11165403
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
CD163 molecule , M130 , MM130 , SCARI1
功能与背景
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
数据库
研究领域
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_825_IHC-Fr_w_23060820_238.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_821_IHC-Fr_w_23060820_678.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_822_IHC-Fr_w_23060820_842.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_823_IHC-Fr_w_23060820_287.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_824_IHC-Fr_w_23060820_707.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/small/GTX42365/GTX42365_826_IHC-Fr_w_23060820_402.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_825_IHC-Fr_w_23060820_238.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_821_IHC-Fr_w_23060820_678.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_822_IHC-Fr_w_23060820_842.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_823_IHC-Fr_w_23060820_287.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_824_IHC-Fr_w_23060820_707.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
![Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365](/upload/website/prouct_img/normal/GTX42365/GTX42365_826_IHC-Fr_w_23060820_402.webp "Anti-CD163 antibody [EDHu-1] used in IHC (Frozen sections) (IHC-Fr). GTX42365")
