GeneTex中国官方网站
  • China

CD19抗体 [HIB19] (PE-Cy7)

Anti-CD19 antibody [HIB19] (PE-Cy7) used in Flow cytometry (FACS). GTX01455-10

目录号 GTX01455-10

文献引用 1684

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 HIB19

同种型

 IgG1

实验应用

 FACS

种属反应

 Human
产品包装
100 test (¥3500)
查看所有 CD19 的产品
产品说明

摘要

The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
FACS 0.25 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

61 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

浓度

0.05 mg/ml (Please refer to the vial label for the specific concentration.)

纯化方式

Purified by affinity chromatography
From tissue culture supernatant

偶联

Phycoerythrin-Cyanine7 (PE-Cy7)

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

CD19 molecule , B4 , CD19 , CVID3

细胞定位

Membrane

功能与背景

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]

数据库

研究领域

產品图片

Anti-CD19 antibody [HIB19] (PE-Cy7) used in Flow cytometry (FACS). GTX01455-10

GTX01455-10 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX01455-10 CD19 antibody [HIB19] (PE-Cy7).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

文献引用

Clone Reference

Benjelloun F et al. Front Immunol 2020; 11:1655 Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.
Bourdely P et al. Immunity 2020; 53 (2):335-352.e8 Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Salzer B et al. Nat Commun 2020; 11 (1):4166 Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Imura Y et al. JCI Insight 2020; 5 (14) CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD.
Zhao NQ et al. PLoS One 2020; 15 (9):e0238347 Natural killer cell phenotype is altered in HIV-exposed seronegative women.
显示更多 +
我要回报文献

产品评论

目前没有使用 CD19 antibody [HIB19] (PE-Cy7) (GTX01455-10) 的产品评论被收录。快发表第一篇产品评论吧！
我要评论产品
Clone Reference
Lartey S et al. J Infect Dis 2020; 221 (1):21-32 Live-Attenuated Influenza Vaccine Induces Tonsillar Follicular T Helper Cell Responses That Correlate With Antibody Induction.
Telesford KM et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (1) Black African and Latino/a identity correlates with increased plasmablasts in MS.
Wiedeman AE et al. J Clin Invest 2020; 130 (1):480-490 Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
Suzuki D et al. Stem Cell Reports 2020; 14 (1):49-59 iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.
Afreen S et al. Cell Death Dis 2020; 11 (1):8 BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells.
Queckb?rner S et al. Stem Cell Res Ther 2020; 11 (1):15 Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile.
Suzuki T et al. J Clin Invest 2020; 130 (2):799-812 Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections.
Hedlund M et al. RMD Open 2020; 6 (1) Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.
Gasser P et al. Nat Commun 2020; 11 (1):165 The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Byrne AJ et al. J Exp Med 2020; 217 (3) Dynamics of human monocytes and airway macrophages during healthy aging and after transplant.
Rohner L et al. Sci Rep 2020; 10 (1):222 Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study.
Huhn O et al. Nat Commun 2020; 11 (1):381 Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy.
Yamamoto EA et al. Nutrients 2020; 12 (2) Low Levels of Vitamin D Promote Memory B Cells in Lupus.
Kudryavtsev I et al. Sci Rep 2020; 10 (1):1059 Imbalance in B cell and T Follicular Helper Cell Subsets in Pulmonary Sarcoidosis.
Yang L et al. Genes Dis 2020; 7 (1):128-137 Novel biallelic TRNT1 mutations lead to atypical SIFD and multiple immune defects.
Pilon C et al. Front Immunol 2020; 11:34 Phenotypic and Transcriptomic Lymphocytes Changes in Allograft Recipients After Intravenous Immunoglobulin Therapy in Kidney Transplant Recipients.
Panda SK et al. Proc Natl Acad Sci U S A 2020; 117 (6):3103-3113 IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.
Wilson TJ et al. Immunology 2020; 159 (4):393-403 Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection.
Rendeiro AF et al. Nat Commun 2020; 11 (1):577 Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.
Marasco M et al. Sci Adv 2020; 6 (5):eaay4458 Molecular mechanism of SHP2 activation by PD-1 stimulation.
Kim KH et al. Oncoimmunology 2020; 9 (1):1722023 Immune-related adverse events are clustered into distinct subtypes by T-cell profiling before and early after anti-PD-1 treatment.
Kim JH et al. Sci Rep 2020; 10 (1):1835 Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients.
Kerntke C et al. Front Immunol 2020; 11:118 There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes.
Mirlekar B et al. Cancer Immunol Res 2020; 8 (3):292-308 B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer.
M?rquez EJ et al. Nat Commun 2020; 11 (1):751 Sexual-dimorphism in human immune system aging.
Schommers P et al. Cell 2020; 180 (3):471-489.e22 Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Lobner E et al. Front Bioeng Biotechnol 2020; 8:49 Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.
Kunishita Y et al. Front Immunol 2020; 11:98 TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis.
Walker LA et al. J Transl Med 2020; 18 (1):63 CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq.
Sekido Y et al. Sci Rep 2020; 10 (1):2988 Some Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn's disease patients versus mucus.
Moral JA et al. Nature 2020; 579 (7797):130-135 ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity.
Okurut S et al. Infect Immun 2020; 88 (3) B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis.
Peluso MJ et al. J Virus Erad 2020; 6 (1):19-26 Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1.
Nguyen T et al. PLoS Pathog 2020; 16 (2):e1008336 The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication.
?yszkiewicz M et al. Nat Commun 2020; 11 (1):1031 Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells.
Booth JS et al. J Transl Med 2020; 18 (1):102 Oral typhoid vaccine Ty21a elicits antigen-specific resident memory CD4+ T cells in the human terminal ileum lamina propria and epithelial compartments.
Golinski ML et al. Front Immunol 2020; 11:32 CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors.
Salomonsson M et al. Front Immunol 2020; 11:321 Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors.
Rinc?n-Ar?valo H et al. Heliyon 2020; 6 (3):e03441 Low frequency of IL-10+ B cells in patients with atherosclerosis is related with inflammatory condition.
Zhang W et al. Nat Commun 2020; 11 (1):1187 Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy.
Kotaki R et al. Sci Rep 2020; 10 (1):4355 Dasatinib exacerbates splenomegaly of mice inoculated with Epstein-Barr virus-infected lymphoblastoid cell lines.
Smith MA et al. Sci Rep 2020; 10 (1):4462 Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus.
Novice T et al. J Clin Immunol 2020; 40 (2):267-276 A Germline Mutation in the C2 Domain of PLCγ2 Associated with Gain-of-Function Expands the Phenotype for PLCG2-Related Diseases.
Miller SM et al. Front Immunol 2020; 11:406 Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice.
Zeng Q et al. Mediators Inflamm 2020; 2020:4176082 Leptin Regulated ILC2 Cell through the PI3K/AKT Pathway in Allergic Rhinitis.
G?mez-Ch?vez F et al. Front Immunol 2020; 11:390 A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns.
Li Y et al. Front Immunol 2020; 11:448 Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease.
Einhaus J et al. Arthritis Res Ther 2020; 22 (1):66 Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Busse M et al. Front Immunol 2020; 11:386 Regulatory B Cells Are Decreased and Impaired in Their Function in Peripheral Maternal Blood in Pre-term Birth.
Alarcon-Barrera JC et al. Anal Bioanal Chem 2020; 412 (10):2353-2363 Lipid metabolism of leukocytes in the unstimulated and activated states.
Martin E et al. JCI Insight 2020; 5 (5) Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.
Umeda M et al. Sci Rep 2020; 10 (1):6010 Thymus and Activation-regulated Chemokine as a Biomarker for IgG4-related Disease.
Wijesinghe A et al. J Biomed Sci 2020; 27 (1):50 Phenotype and functionality of follicular helper T cells in patients with acute dengue infection.
Wong SW et al. Sci Adv 2020; 6 (15):eaaw0158 Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking.
Shopova IA et al. mBio 2020; 11 (2) Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus.
Anderson EJ et al. Vaccines (Basel) 2020; 8 (1) Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine.
Jackson-Jones LH et al. Immunity 2020; 52 (4):700-715.e6 Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
M?noret S et al. Transplantation 2020; 104 (4):715-723 In Vivo Analysis of Human Immune Responses in Immunodeficient Rats.
Caduff N et al. PLoS Pathog 2020; 16 (4):e1008477 Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice.
El-Neanaey WA et al. Int J Hematol Oncol Stem Cell Res 2020; 14 (1):27-37 Evaluation of CD160 and CD200 Expression as Differentiating Markers between Chronic Lymphocytic Leukemia and Other Mature B-Cell Neoplasms.
Samassa F et al. Cell Microbiol 2020; 22 (5):e13166 Shigella impairs human T lymphocyte responsiveness by hijacking actin cytoskeleton dynamics and T cell receptor vesicular trafficking.
De Martino M et al. Sci Rep 2020; 10 (1):7057 HMGA1-pseudogene7 transgenic mice develop B cell lymphomas.
Aguiar FS et al. Stem Cell Res Ther 2020; 11 (1):167 Autologous bone marrow-derived mononuclear cell therapy in three patients with severe asthma.
James KR et al. Nat Immunol 2020; 21 (3):343-353 Distinct microbial and immune niches of the human colon.
J Clin Immunol 2020; 40 (Suppl 1):1-163 2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference.
Ainai A et al. Microbiol Immunol 2020; 64 (4):313-325 Human immune responses elicited by an intranasal inactivated H5 influenza vaccine.
Di Genua C et al. Cancer Cell 2020; 37 (5):690-704.e8 C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Tanno H et al. Sci Adv 2020; 6 (17):eaay9093 A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires.
Grifoni A et al. Cell 2020; 181 (7):1489-1501.e15 Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.
Takata K et al. Diabetes Metab Syndr Obes 2020; 13:1491-1497 Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee.
Loff S et al. Mol Ther Oncolytics 2020; 17:408-420 Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia.
Barberi C et al. Blood Adv 2020; 4 (10):2297-2307 Myeloma cells induce the accumulation of activated CD94low NK cells by cell-to-cell contacts involving CD56 molecules.
Zhao NQ et al. Front Immunol 2020; 11:829 Treated HIV Infection Alters Phenotype but Not HIV-Specific Function of Peripheral Blood Natural Killer Cells.
Li Z et al. J Clin Lab Anal 2020; 34 (5):e23155 High-dimensional single-cell proteomics analysis reveals the landscape of immune cells and stem-like cells in renal tumors.
Sun X et al. Nat Commun 2020; 11 (1):2421 Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation.
Sun B et al. Orphanet J Rare Dis 2020; 15 (1):131 LIG4 syndrome: clinical and molecular characterization in a Chinese cohort.
Garner-Spitzer E et al. Front Immunol 2020; 11:860 Obesity and Sex Affect the Immune Responses to Tick-Borne Encephalitis Booster Vaccination.
Roschewski M et al. Sci Immunol 2020; 5 (48) Inhibition of Bruton tyrosine kinase in patients with severe COVID-19.
Ruiz-Aparicio PF et al. Int J Mol Sci 2020; 21 (10) Dual Targeting of Stromal Cell Support and Leukemic Cell Growth by a Peptidic PKC Inhibitor Shows Effectiveness against B-ALL.
Pearson FE et al. Clin Transl Immunology 2020; 9 (6):e1141 Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate na?ve and memory WT1-specific CD8+ T cells.
Gilmore W et al. J Neuroinflammation 2020; 17 (1):189 Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis.
Schwerd T et al. Bone Res 2020; 8:24 A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
Yan H et al. ACS Appl Mater Interfaces 2020; 12 (17):19324-19336 Glyco-Modification of Mucin Hydrogels to Investigate Their Immune Activity.
Magatti M et al. Front Immunol 2020; 11:1156 B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells.
Wagstaffe HR et al. J Clin Invest 2020; 130 (7):3936-3946 Ebola virus glycoprotein stimulates IL-18-dependent natural killer cell responses.
Bennstein SB et al. Elife 2020; 9 Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells.
Li Z et al. Clin Transl Immunology 2020; 9 (7):e1156 Targeting CD83 in mantle cell lymphoma with anti-human CD83 antibody.
Scharf L et al. J Virol 2020; 94 (14) Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection.
Riese P et al. Vaccines (Basel) 2020; 8 (2) Responsiveness to Influenza Vaccination Correlates with NKG2C-Expression on NK Cells.
Garrido-Martin EM et al. J Immunother Cancer 2020; 8 (2) M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer.
Marzaioli V et al. Front Immunol 2020; 11:1406 Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation.
Hood SP et al. Elife 2020; 9 Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data.
Mendes-Frias A et al. J Transl Autoimmun 2020; 3:100056 Dysregulation of glycerophospholipid metabolism during Beh?et's disease contributes to a pro-inflammatory phenotype of circulating monocytes.
Gruber CN et al. Immunity 2020; Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function.
Zhou R et al. Immunity 2020; Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses.
Hu EY et al. JCI Insight 2020; 5 (12) LC-FACSeq is a method for detecting rare clones in leukemia.
Abu-Shahba AG et al. Tissue Eng Regen Med 2020; 17 (4):477-493 Proangiogenic Hypoxia-Mimicking Agents Attenuate Osteogenic Potential of Adipose Stem/Stromal Cells.
Li M et al. Nat Commun 2020; 11 (1):4051 Clearance of HIV infection by selective elimination of host cells capable of producing HIV.
Colomb F et al. Cell Rep 2020; 32 (5):107991 Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy.
Velasco-Hernandez T et al. J Immunother Cancer 2020; 8 (2) Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope.
Ye C et al. FASEB J 2020; A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
Kr?ger R et al. Front Immunol 2020; 11:1593 CD70 Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman.
Stoszko M et al. Sci Adv 2020; 6 (33):eaba6617 Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.
B?zie S et al. Front Immunol 2020; 11:1496 IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection.
Cytlak U et al. Immunity 2020; 53 (2):353-370.e8 Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.
Richards KA et al. NPJ Vaccines 2020; 5:77 Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans.
Giron LB et al. EBioMedicine 2020; 59:102945 Interferon-α alters host glycosylation machinery during treated HIV infection.
Pierini S et al. JCI Insight 2020; 5 (16) Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
Diedrich T et al. PLoS One 2020; 15 (3):e0230307 Characterization of the immune cell landscape of patients with NAFLD.
Wierzbinska JA et al. Genome Med 2020; 12 (1):29 Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Stebegg M et al. Elife 2020; 9 Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination.
Schorer M et al. Nat Commun 2020; 11 (1):1522 Rapid expansion of Treg cells protects from collateral colitis following a viral trigger.
Villazala-Merino S et al. J Allergy Clin Immunol 2020; 145 (3):958-967.e5 Allergen-specific IgE levels and the ability of IgE-allergen complexes to cross-link determine the extent of CD23-mediated T-cell activation.
Easterhoff D et al. JCI Insight 2020; 5 (2) HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
Ryu S et al. Arthritis Res Ther 2020; 22 (1):63 Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis.
Deal C et al. Front Immunol 2020; 11:415 Intact B-Cell Signaling and Function With Host B-Cells 47 Years After Transplantation for X-SCID.
Harris LD et al. Front Cell Infect Microbiol 2020; 10:120 Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.
Gan H et al. Sci Adv 2020; 6 (14):eaay2793 B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response.
Okumura G et al. J Exp Med 2020; 217 (4) Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.
Seng A et al. Blood Adv 2020; 4 (7):1325-1339 Coexpression of FOXP3 and a Helios isoform enhances the effectiveness of human engineered regulatory T cells.
H?usler D et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (3) Glatiramer acetate immune modulates B-cell antigen presentation in treatment of MS.
Tufa DM et al. Sci Rep 2020; 10 (1):6335 Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage.
Rosser EC et al. Cell Metab 2020; 31 (4):837-851.e10 Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Marsh-Wakefield F et al. Clin Transl Immunology 2020; 9 (5):e01133 IgG3 + B cells are associated with the development of multiple sclerosis.
Pollara J et al. Front Immunol 2020; 11:713 Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART? Molecules.
Haschka D et al. Front Immunol 2020; 11:594 Expansion of Neutrophils and Classical and Nonclassical Monocytes as a Hallmark in Relapsing-Remitting Multiple Sclerosis.
Fox A et al. Sci Rep 2020; 10 (1):7651 Cyto-Feature Engineering: A Pipeline for Flow Cytometry Analysis to Uncover Immune Populations and Associations with Disease.
Hanna SJ et al. Diabetologia 2020; 63 (6):1174-1185 Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Reyes M et al. Nat Med 2020; 26 (3):333-340 An immune-cell signature of bacterial sepsis.
Crawford LB et al. Microorganisms 2020; 8 (4) Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice.
Schulz-Kuhnt A et al. Front Immunol 2020; 11:691 ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.
Salio M et al. Proc Natl Acad Sci U S A 2020; 117 (19):10465-10475 Ligand-dependent downregulation of MR1 cell surface expression.
Goodwin M et al. Sci Adv 2020; 6 (19):eaaz0571 CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells.
Esaulova E et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (4) Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.
Szentkereszty M et al. Pathol Oncol Res 2020; 26 (2):1117-1128 Effect of COPD on Inflammation, Lymphoid Functions and Progression-Free Survival during First-Line Chemotherapy in Advanced Non-small Cell Lung Cancer.
Mola S et al. PLoS One 2020; 15 (5):e0233543 A transcriptome-based approach to identify functional modules within and across primary human immune cells.
Jung J et al. Clin Transl Immunology 2020; 9 (6):e1140 Synovial fluid CD69+CD8+ T cells with tissue-resident phenotype mediate perforin-dependent citrullination in rheumatoid arthritis.
Durant L et al. Microbiome 2020; 8 (1):88 Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease.
Ahl PJ et al. Commun Biol 2020; 3 (1):305 Met-Flow, a strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations.
Loughland JR et al. Clin Transl Immunology 2020; 9 (6):e1144 Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection.
Lindesmith LC et al. Cell Mol Gastroenterol Hepatol 2020; 10 (2):245-267 Virus-Host Interactions Between Nonsecretors and Human Norovirus.
Cheng L et al. JCI Insight 2020; 5 (11) Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq.
Aguilar-Brise?o JA et al. Nat Commun 2020; 11 (1):3177 TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis.
Mencarelli A et al. J Leukoc Biol 2020; 107 (5):797-807 A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.
Martin-Fernandez M et al. Cell Rep 2020; 31 (6):107633 Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions.
Arcangeli S et al. Front Immunol 2020; 11:1217 Next-Generation Manufacturing Protocols Enriching TSCM CAR T Cells Can Overcome Disease-Specific T Cell Defects in Cancer Patients.
Verstappen GM et al. J Autoimmun 2020; 109:102439 Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sj?gren's syndrome reveals a pathogenic signature.
Tanimura K et al. ERJ Open Res 2020; 6 (2) Low serum free light chain is associated with risk of COPD exacerbation.
Bowyer G et al. J Exp Med 2020; 217 (7) Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells.
Kim J et al. Arthritis Res Ther 2020; 22 (1):173 Clinical and histological significance of urinary CD11c+ macrophages in lupus nephritis.
Ratajczak MZ et al. Stem Cell Rev Rep 2020; SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45- Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 Inflammasome.
Greenshields-Watson A et al. Cell Rep 2020; 32 (2):107885 CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Saxena S et al. Sci Rep 2020; 10 (1):12405 Identification of TNFAIP3 as relapse biomarker and potential therapeutic target for MOG antibody associated diseases.
Abraham J et al. Front Immunol 2020; 11:1430 Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner.
Badura R et al. Front Cell Infect Microbiol 2020; 10:347 Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment.
Schulte-Schrepping J et al. Cell 2020; Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Masterman KA et al. J Immunother Cancer 2020; 8 (2) Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate na?ve and memory NY-ESO-1-specific CD8+ T cells.
Johnson BZ et al. Front Immunol 2020; 11:1481 Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response.
Rivera-Correa J et al. PLoS Negl Trop Dis 2020; 14 (7):e0008466 Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections.
Reginia A et al. Brain Sci 2020; 10 (7) Markers of Regenerative Processes in Patients with Bipolar Disorder: A Case-control Study.
Kholodnyuk I et al. J Clin Med 2020; 9 (7) Chemokine Receptors CCR1 and CCR2 on Peripheral Blood Mononuclear Cells of Newly Diagnosed Patients with the CD38-Positive Chronic Lymphocytic Leukemia.
Sztein MB et al. Sci Rep 2020; 10 (1):13581 Salmonella enterica serovar Typhi exposure elicits ex vivo cell-type-specific epigenetic changes in human gut cells.
Kreye J et al. bioRxiv 2020; A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Rai R et al. Nat Commun 2020; 11 (1):4034 Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott -?Aldrich Syndrome.
Wege AK et al. J Transl Med 2020; 18 (1):316 A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM).
Meikle CK et al. PLoS One 2020; 15 (8):e0236966 Platelet-T cell aggregates in lung cancer patients: Implications for thrombosis.
Benjelloun F et al. Front Immunol 2020; 11:1655 Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.
Bourdely P et al. Immunity 2020; 53 (2):335-352.e8 Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Salzer B et al. Nat Commun 2020; 11 (1):4166 Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Imura Y et al. JCI Insight 2020; 5 (14) CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD.
Zhao NQ et al. PLoS One 2020; 15 (9):e0238347 Natural killer cell phenotype is altered in HIV-exposed seronegative women.
Guo N et al. Cell Mol Immunol 2019; 16 (6):568-579 A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis.
Perugino CA et al. J Allergy Clin Immunol 2019; 143 (2):736-745.e6 Identification of galectin-3 as an autoantigen in patients with IgG4-related disease.
Ratliff ML et al. J Autoimmun 2019; 96:158-167 ARID3a gene profiles are strongly associated with human interferon alpha production.
Loughland JR et al. J Infect Dis 2019; 219 (4):660-671 Plasmodium falciparum Activates CD16+ Dendritic Cells to Produce Tumor Necrosis Factor and Interleukin-10 in Subpatent Malaria.
Booth JS et al. Int Immunol 2019; 31 (2):101-116 Effect of the live oral attenuated typhoid vaccine, Ty21a, on systemic and terminal ileum mucosal CD4+ T memory responses in humans.
Rozmus J et al. Biol Blood Marrow Transplant 2019; 25 (3):451-458 Comprehensive B Cell Phenotyping Profile for Chronic Graft-versus-Host Disease Diagnosis.
Rataj F et al. Br J Cancer 2019; 120 (1):79-87 High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
Wiedemann GM et al. Transl Oncol 2019; 12 (2):350-360 Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma.
Fu J et al. Cell Stem Cell 2019; 24 (2):227-239.e8 Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
Senda T et al. Mucosal Immunol 2019; 12 (2):378-389 Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
Schlenner S et al. Ann Rheum Dis 2019; 78 (3):342-349 NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.
Tan C et al. J Biol Chem 2019; 294 (7):2470-2485 A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates.
Tong Y et al. MAbs 2019; 11 (2):401-410 De novo generation of specific human IgGs by in vitro immunization using autologous proteins containing immunogenic p-nitrophenylalanine.
Higdon LE et al. J Immunol Methods 2019; 466:17-23 Optimization of single-cell plate sorting for high throughput sequencing applications.
Ha D et al. Proc Natl Acad Sci U S A 2019; 116 (2):609-618 Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Lundqvist S et al. Immunology 2019; 156 (3):259-269 Frequency and immunophenotype of IL10-producing regulatory B cells in optic neuritis.
Kuranda K et al. Mol Ther Methods Clin Dev 2019; 13:112-120 In?Vitro Expansion of Anti-viral T Cells from Cord Blood by Accelerated Co-cultured Dendritic Cells.
Nayak RC et al. Nat Commun 2019; 10 (1):46 The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors.
Koppejan H et al. Arthritis Res Ther 2019; 21 (1):3 Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis.
Lechner A et al. Oncoimmunology 2019; 8 (3):1535293 Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma.
Blijdorp ICJ et al. Arthritis Rheumatol 2019; 71 (3):392-402 Expansion of Interleukin-22- and Granulocyte-Macrophage Colony-Stimulating Factor-Expressing, but Not Interleukin-17A-Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis.
Zhang X et al. JCI Insight 2019; 4 (2) A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity.
Gorman JA et al. Front Immunol 2019; 10:44 The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Luo Z et al. AIDS 2019; 33 (1):33-44 Increased influenza-specific antibody avidity in HIV-infected women compared with HIV-infected men on antiretroviral therapy.
Shannon I et al. Sci Rep 2019; 9 (1):791 Differences in the influenza-specific CD4 T cell immunodominance hierarchy and functional potential between children and young adults.
Schmidl C et al. Nat Chem Biol 2019; 15 (3):232-240 Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL.
Sol?-Riera C et al. Sci Rep 2019; 9 (1):834 Orthohantaviruses belonging to three phylogroups all inhibit apoptosis in infected target cells.
Kriegsmann K et al. Blood Cancer J 2019; 9 (2):13 Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients.
Goodridge JP et al. Nat Commun 2019; 10 (1):514 Remodeling of secretory lysosomes during education tunes functional potential in NK cells.
Arrey F et al. Front Immunol 2019; 10:89 Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens.
Freitas GRR et al. Aging Dis 2019; 10 (1):49-61 Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population.
Kaur M et al. J Immunol 2019; 202 (6):1885-1894 Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice.
Cypris O et al. Clin Epigenetics 2019; 11 (1):19 Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells.
Faliti CE et al. J Exp Med 2019; 216 (2):317-336 P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus.
Franco LM et al. J Exp Med 2019; 216 (2):384-406 Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses.
Li Y et al. Front Immunol 2019; 10:63 Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8+ T Cells.
Bouafia A et al. J Clin Invest 2019; 129 (3):1047-1060 Loss of ARHGEF1 causes a human primary antibody deficiency.
Wen Z et al. Nat Immunol 2019; 20 (3):313-325 N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation.
Anzilotti C et al. Nat Immunol 2019; 20 (3):350-361 An essential role for the Zn2+ transporter ZIP7 in B cell development.
Smith MJ et al. JCI Insight 2019; 4 (3) Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity.
Gonnord P et al. Oncoimmunology 2019; 8 (4):e1570774 Multiparametric analysis of CD8+ T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy.
Papachristofilou A et al. J Immunother Cancer 2019; 7 (1):38 Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer.
G?rtner K et al. J Extracell Vesicles 2019; 8 (1):1573051 Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL.
R?destad E et al. Front Immunol 2019; 10:189 Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion.
Shah NJ et al. Nat Biotechnol 2019; 37 (3):293-302 An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation.
Du H et al. Cancer Cell 2019; 35 (2):221-237.e8 Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.
Lepzien R et al. J Leukoc Biol 2019; 105 (4):797-807 Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.
Zhang L et al. Mol Pain 2019; 15:1744806919828921 ERK and p38 contribute to the regulation of nociceptin and the nociceptin receptor in human peripheral blood leukocytes.
Eken A et al. Front Immunol 2019; 10:217 Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells.
Luo Z et al. Microbiome 2019; 7 (1):25 Systemic translocation of Staphylococcus drives autoantibody production in HIV disease.
Murray D et al. Blood Adv 2019; 3 (4):519-530 Progression of mycosis fungoides occurs through divergence of tumor immunophenotype by differential expression of HLA-DR.
Tardif V et al. Nat Commun 2019; 10 (1):823 Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV.
Furie R et al. J Clin Invest 2019; 129 (3):1359-1371 Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus.
Schulthess J et al. Immunity 2019; 50 (2):432-445.e7 The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Walk J et al. Nat Commun 2019; 10 (1):874 Outcomes of controlled human malaria infection after BCG vaccination.
G?mez-Ch?vez F et al. Front Immunol 2019; 10:285 Maternal Immune Response During Pregnancy and Vertical Transmission in Human Toxoplasmosis.
Huijbers MG et al. Neurol Neuroimmunol Neuroinflamm 2019; 6 (3):e547 MuSK myasthenia gravis monoclonal antibodies: Valency dictates pathogenicity.
Wiedemann A et al. PLoS One 2019; 14 (2):e0212525 B cell subset distribution in human bone marrow is stable and similar in left and right femur: An instructive case.
Kumar P et al. Blood Adv 2019; 3 (4):681-691 HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells.
Semple KM et al. Clin Transl Sci 2019; 12 (3):283-290 Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD20-Specific Cytotoxicity Induced by?Ofatumumab.
Sagebiel AF et al. Nat Commun 2019; 10 (1):975 Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine.
Foote JR et al. Front Immunol 2019; 10:188 Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets.
Latour S et al. Cancers (Basel) 2019; 11 (3) Role of Calcium Signaling in GA101-Induced Cell Death in Malignant Human B Cells.
Tripathi T et al. Immunohorizons 2019; 3 (3):110-120 Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease.
Wang K et al. Cell Rep 2019; 26 (10):2580-2592.e7 Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells.
Lu E et al. Nature 2019; 567 (7747):244-248 S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8.
Hussain K et al. Front Immunol 2019; 10:390 Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
Nivarthi UK et al. EBioMedicine 2019; 41:465-478 Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model.
Perdomo-Celis F et al. Pathogens 2019; 8 (1) HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice.
Krebs SJ et al. Immunity 2019; 50 (3):677-691.e13 Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Galloway SAE et al. Front Immunol 2019; 10:319 Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Maidji E et al. Viruses 2019; 11 (3) Cellular HIV Reservoirs and Viral Rebound from the Lymphoid Compartments of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine (EFdA)-Suppressed Humanized Mice.
Ferreira CC et al. Arthritis Res Ther 2019; 21 (1):75 Impact of synthetic and biological immunomodulatory therapy on the duration of 17DD yellow fever vaccine-induced immunity in rheumatoid arthritis.
Booth JS et al. Front Immunol 2019; 10:424 Attenuated Oral Typhoid Vaccine Ty21a Elicits Lamina Propria and Intra-Epithelial Lymphocyte Tissue-Resident Effector Memory CD8 T Responses in the Human Terminal Ileum.
Jones D et al. PLoS Pathog 2019; 15 (3):e1007650 Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function.
Mennan C et al. Stem Cell Res Ther 2019; 10 (1):99 A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells.
Russo MA et al. J Neuroinflammation 2019; 16 (1):63 Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome.
Oda H et al. Front Immunol 2019; 10:479 Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC.
Tomi? S et al. Front Immunol 2019; 10:475 Prostaglanin-E2 Potentiates the Suppressive Functions of Human Mononuclear Myeloid-Derived Suppressor Cells and Increases Their Capacity to Expand IL-10-Producing Regulatory T Cell Subsets.
Wanjalla CN et al. Front Immunol 2019; 10:408 Adipose Tissue in Persons With HIV Is Enriched for CD4+ T Effector Memory and T Effector Memory RA+ Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression With Increasing Glucose Intolerance.
Felices M et al. Blood Adv 2019; 3 (6):897-907 Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL.
Hudspeth K et al. Clin Exp Immunol 2019; 196 (2):226-236 Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus.
Barba T et al. Front Immunol 2019; 10:513 Highly Variable Sialylation Status of Donor-Specific Antibodies Does Not Impact Humoral Rejection Outcomes.
Tufa DM et al. Front Immunol 2019; 10:510 Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation.
Karahan GE et al. Transplantation 2019; 103 (4):716-723 An Easy and Sensitive Method to Profile the Antibody Specificities of HLA-specific Memory B Cells.
Mannerstr?m B et al. Epigenetics 2019; 14 (4):352-364 Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles.
Do P et al. J Immunol 2019; 202 (9):2806-2816 Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells.
Rapp M et al. J Exp Med 2019; 216 (5):1170-1181 CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes.
von Essen MR et al. Cells 2019; 8 (3) IL-6, IL-12, and IL-23 STAT-Pathway Genetic Risk and Responsiveness of Lymphocytes in Patients with Multiple Sclerosis.
Jeong JH et al. Immune Netw 2019; 19 (3):e21 Prominent Inflammatory Features of Monocytes/Macrophages in Acute Calcium Pyrophosphate Crystal Arthritis: a Comparison with Acute Gouty Arthritis.
Hua P et al. Sci Rep 2019; 9 (1):5300 Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.
Yap HY et al. Adv Virol 2019; 2019:6464521 Epstein-Barr Virus- (EBV-) Immortalized Lymphoblastoid Cell Lines (LCLs) Express High Level of CD23 but Low CD27 to Support Their Growth.
Cron MA et al. Front Immunol 2019; 10:539 Causes and Consequences of miR-150-5p Dysregulation in Myasthenia Gravis.
H?rd J et al. Genome Biol 2019; 20 (1):68 Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing.
Belizaire R et al. Blood Adv 2019; 3 (7):969-979 Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease.
Guimar?es FTL et al. Front Pediatr 2019; 7:114 Pediatric Patients With Steroid-Sensitive Nephrotic Syndrome Have Higher Expression of T Regulatory Lymphocytes in Comparison to Steroid-Resistant Disease.
Booth JS et al. Hum Vaccin Immunother 2019; 15 (6):1409-1420 Association between S. Typhi-specific memory CD4+ and CD8+ T responses in the terminal ileum mucosa and in peripheral blood elicited by the live oral typhoid vaccine Ty21a in humans.
Zhou L et al. Nature 2019; 568 (7752):405-409 Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2.
Nienen M et al. Front Immunol 2019; 10:593 The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains.
Schiroli G et al. Cell Stem Cell 2019; 24 (4):551-565.e8 Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response.
Zimmerman KA et al. J Am Soc Nephrol 2019; 30 (5):767-781 Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species.
Easterbrook J et al. Stem Cell Reports 2019; 12 (5):1056-1068 Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo.
Pavel-Dinu M et al. Nat Commun 2019; 10 (1):1634 Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Planchais C et al. Cell Rep 2019; 27 (2):572-585.e7 HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells.
Ye Y et al. Arthritis Res Ther 2019; 21 (1):92 Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis.
K?ksal H et al. Blood Adv 2019; 3 (8):1230-1243 Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma.
Wang H et al. Theranostics 2019; 9 (8):2315-2324 Human LAP+GARP+FOXP3+ regulatory T cells attenuate xenogeneic graft versus host disease.
Cassetta L et al. Cancer Cell 2019; 35 (4):588-602.e10 Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Zimmermann M et al. Front Immunol 2019; 10:829 Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells.
Medina BD et al. J Exp Med 2019; 216 (6):1359-1376 Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity.
Adhikary SR et al. Purinergic Signal 2019; 15 (2):177-192 Altered donor P2X7 activity in human leukocytes correlates with P2RX7 genotype but does not affect the development of graft-versus-host disease in humanised mice.
Ferdosi SR et al. Nat Commun 2019; 10 (1):1842 Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes.
Forlani G et al. Front Microbiol 2019; 10:819 HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients.
Jiang DM et al. Oncotarget 2019; 10 (31):2947-2958 Phase I study of local radiation and tremelimumab in patients with inoperable locally recurrent or metastatic breast cancer.
Terahara K et al. BMC Res Notes 2019; 12 (1):242 A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro.
Saucourt C et al. Stem Cells Transl Med 2019; 8 (8):822-832 Design and Validation of an Automated Process for the Expansion of Peripheral Blood-Derived CD34+ Cells for Clinical Use After Myocardial Infarction.
Staniek J et al. Front Immunol 2019; 10:951 TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Fernandez IZ et al. J Exp Med 2019; 216 (6):1255-1267 A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.
Zhang Z et al. J Exp Med 2019; 216 (6):1311-1327 Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance.
Lossos C et al. Cancer Discov 2019; 9 (7):944-961 Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents.
Karimzadeh H et al. Gastroenterology 2019; 156 (6):1820-1833 Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.
Xia Y et al. Gastroenterol Res Pract 2019; 2019:5436961 Optimizing the Method of Cell Separation from Bile of Patients with Cholangiocarcinoma for Flow Cytometry.
Suurmond J et al. JCI Insight 2019; 4 (9) Patterns of ANA+ B cells for SLE patient stratification.
Ghofrani J et al. Eur J Immunol 2019; 49 (8):1153-1166 Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.
Zhang F et al. Nat Immunol 2019; 20 (7):928-942 Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Zhang W et al. Front Microbiol 2019; 10:977 Probiotic Lactobacillus rhamnosus GG Induces Alterations in Ileal Microbiota With Associated CD3-CD19-T-bet+IFNγ+/- Cell Subset Homeostasis in Pigs Challenged With Salmonella enterica Serovar 4,[5],12:i:.
Durand M et al. J Exp Med 2019; 216 (7):1561-1581 Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses.
Lo TH et al. PLoS One 2019; 14 (5):e0216368 Examination of CD302 as a potential therapeutic target for acute myeloid leukemia.
Dieudonn? Y et al. J Autoimmun 2019; 102:150-158 Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN.
Lindestam Arlehamn CS et al. J Immunol 2019; 203 (1):84-92 Widespread Tau-Specific CD4 T Cell Reactivity in the General Population.
Adelman ER et al. Cancer Discov 2019; 9 (8):1080-1101 Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia.
Umeshappa CS et al. Nat Commun 2019; 10 (1):2150 Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines.
Golebski K et al. Nat Commun 2019; 10 (1):2162 IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation.
Kim ST et al. J Immunother Cancer 2019; 7 (1):126 Recurrent pseudogout after therapy with immune checkpoint inhibitors: a case report with immunoprofiling of synovial fluid at each flare.
Deng J et al. Cancer Immunol Res 2019; 7 (7):1079-1090 Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Shea LK et al. Blood Cancer J 2019; 9 (6):47 Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status.
Juno JA et al. J Virol 2019; 93 (11) Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of In Vitro versus In Vivo Models.
Zumaquero E et al. Elife 2019; 8 IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.
Garcia-Perez JE et al. Front Immunol 2019; 10:998 CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade.
Watanabe A et al. JCI Insight 2019; 4 (10) Self-tolerance curtails the B cell repertoire to microbial epitopes.
Beaussant-Cohen S et al. J Allergy Clin Immunol 2019; 144 (2):606-608.e4 Combined immunodeficiency in a patient with c-Rel deficiency.
Watanabe A et al. Cell 2019; 177 (5):1124-1135.e16 Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Scharenberg M et al. Front Immunol 2019; 10:1116 Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells.
Gadalla R et al. Front Oncol 2019; 9:415 Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.
Perrier-Groult E et al. PLoS One 2019; 14 (5):e0217183 Evaluation of the biocompatibility and stability of allogeneic tissue-engineered cartilage in humanized mice.
Jimenez Vera E et al. PLoS One 2019; 14 (5):e0217163 Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients.
Ritter M et al. PLoS Negl Trop Dis 2019; 13 (5):e0007436 Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment.
Finotello F et al. Genome Med 2019; 11 (1):34 Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data.
Lee EJ et al. Int J Mol Sci 2019; 20 (10) Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis.
Fine N et al. Blood Adv 2019; 3 (10):1622-1637 Primed PMNs in healthy mouse and human circulation are first responders during acute inflammation.
Sebode M et al. Front Immunol 2019; 10:1065 Inflammatory Phenotype of Intrahepatic Sulfatide-Reactive Type II NKT Cells in Humans With Autoimmune Hepatitis.
Chatterjee B et al. PLoS Pathog 2019; 15 (5):e1007748 CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo.
Nienhaus F et al. Molecules 2019; 24 (11) Phagocytosis of a PFOB-Nanoemulsion for 19F Magnetic Resonance Imaging: First Results in Monocytes of Patients with Stable Coronary Artery Disease and ST-Elevation Myocardial Infarction.
Park SH et al. Nucleic Acids Res 2019; 47 (15):7955-7972 Highly efficient editing of the?β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease.
Agraz-Doblas A et al. Haematologica 2019; 104 (6):1176-1188 Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.
Salomonsson M et al. Clin Exp Allergy 2019; 49 (6):874-882 Circulating mast cell progenitors correlate with reduced lung function in allergic asthma.
Oko LM et al. PLoS Pathog 2019; 15 (6):e1007849 Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression.
Ardain A et al. Nature 2019; 570 (7762):528-532 Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Hill DL et al. J Exp Med 2019; 216 (8):1857-1873 The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.
Celis-Gutierrez J et al. Cell Rep 2019; 27 (11):3315-3330.e7 Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Xiao S et al. Stem Cells Int 2019; 2019:9158016 IL-10 Gene-Modified Human Amniotic Mesenchymal Stem Cells Augment Regenerative Wound Healing by Multiple Synergistic Effects.
Palomares Cabeza V et al. Front Bioeng Biotechnol 2019; 7:142 Pediatric Mesenchymal Stem Cells Exhibit Immunomodulatory Properties Toward Allogeneic T and B Cells Under Inflammatory Conditions.
Grau-Vorster M et al. Stem Cell Res Ther 2019; 10 (1):164 HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study.
Pollmann R et al. Front Immunol 2019; 10:1375 Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris.
Haas JT et al. Nat Metab 2019; 1 (6):604-614 Transcriptional Network Analysis Implicates Altered Hepatic Immune Function in NASH development and resolution.
Ca?ete PF et al. J Exp Med 2019; 216 (8):1843-1856 Regulatory roles of IL-10-producing human follicular T cells.
Arazi A et al. Nat Immunol 2019; 20 (7):902-914 The immune cell landscape in kidneys of patients with lupus nephritis.
Schoofs T et al. Immunity 2019; 50 (6):1513-1529.e9 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
van Langelaar J et al. Ann Neurol 2019; 86 (2):264-278 Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis.
Lopes AP et al. Front Immunol 2019; 10:1335 MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sj?gren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1.
Jiang M et al. Mediators Inflamm 2019; 2019:3140183 ILC2s Induce Adaptive Th2-Type Immunity in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Liechti T et al. J Exp Med 2019; 216 (9):2071-2090 Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells.
da Costa-Rocha IA et al. Front Immunol 2019; 10:1211 Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine.
Clarke J et al. J Exp Med 2019; 216 (9):2128-2149 Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer.
Chapuis AG et al. Nat Med 2019; 25 (7):1064-1072 T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.
Ryzhov S et al. J Am Heart Assoc 2019; 8 (13):e010874 Number of Circulating CD 73-Expressing Lymphocytes Correlates With Survival After Cardiac Arrest.
Munteanu AN et al. Exp Ther Med 2019; 18 (3):1693-1700 Peripheral immune cell markers in children with recurrent respiratory infections in the absence of primary immunodeficiency.
Boileau M et al. Nat Commun 2019; 10 (1):2891 Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness.
Ma W et al. BMC Mol Cell Biol 2019; 20 (1):20 Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose.
Wang C et al. EBioMedicine 2019; 45:578-587 Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.
Armand P et al. Blood 2019; 134 (1):22-29 PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation.
Choi YH et al. J Immunother Cancer 2019; 7 (1):168 IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells.
Kurupati RK et al. Aging (Albany NY) 2019; 11 (13):4367-4381 Age-related changes in B cell metabolism.
Inagaki-Katashiba N et al. Eur J Immunol 2019; 49 (11):2051-2062 Statins can suppress DC-mediated Th2 responses through the repression of OX40-ligand and CCL17 expression.
Zhang J et al. Sci Rep 2019; 9 (1):10090 Circulating CXCR3+ Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients.
Kibata K et al. J Blood Med 2019; 10:217-226 The immunomodulatory-drug, lenalidomide, sustains and enhances interferon-α production by human plasmacytoid dendritic cells.
Bonaccorsi I et al. Front Immunol 2019; 10:1503 Symptomatic Carotid Atherosclerotic Plaques Are Associated With Increased Infiltration of Natural Killer (NK) Cells and Higher Serum Levels of NK Activating Receptor Ligands.
Kato R et al. Front Immunol 2019; 10:1619 CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity.
Serwas NK et al. Nat Commun 2019; 10 (1):3106 Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.
Allden SJ et al. Am J Respir Crit Care Med 2019; 200 (2):209-219 The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis.
Meckiff BJ et al. J Immunol 2019; 203 (5):1276-1287 Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells.
Hartmann FJ et al. Cell Rep 2019; 28 (3):819-831.e4 Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy.
Nowak WN et al. Mediators Inflamm 2019; 2019:1868170 Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo.
Kim JW et al. Immune Netw 2019; 19 (4):e26 Circulating CCR7loPD-1hi Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sj?gren's Syndrome.
Nerreter T et al. Nat Commun 2019; 10 (1):3137 Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T.
Wang H et al. Nat Commun 2019; 10 (1):3254 Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity.
Banga R et al. PLoS Pathog 2019; 15 (7):e1007918 Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.
Ackermann C et al. Sci Rep 2019; 9 (1):10624 HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.
Shih T et al. Front Immunol 2019; 10:1652 RNAi Transfection Optimized in Primary Na?ve B Cells for the Targeted Analysis of Human Plasma Cell Differentiation.
Cho A et al. Cell Rep 2019; 28 (4):909-922.e6 Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease.
Faleiro R et al. Clin Transl Immunology 2019; 8 (7):e01071 Crohn's disease is facilitated by a disturbance of programmed death-1 ligand 2 on blood dendritic cells.
Bancroft T et al. J Exp Med 2019; 216 (10):2331-2347 Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
Solimani F et al. Front Immunol 2019; 10:1808 Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus.
Campi-Azevedo AC et al. Emerg Infect Dis 2019; 25 (8):1511-1521 17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil.
Becker M et al. Mol Metab 2019; 28:73-82 Short-term cold exposure supports human Treg induction in?vivo.
Leite Pereira A et al. Front Immunol 2019; 10:1777 Characterization of Leukocytes From HIV-ART Patients Using Combined Cytometric Profiles of 72 Cell Markers.
Kildey K et al. Front Immunol 2019; 10:1877 Specialized Roles of Human Natural Killer Cell Subsets in Kidney Transplant Rejection.
Yun JW et al. Cancers (Basel) 2019; 11 (8) A Novel Type of Blood Biomarker: Distinct Changes of Cytokine-Induced STAT Phosphorylation in Blood T Cells Between Colorectal Cancer Patients and Healthy Individuals.
Nevalainen T et al. Immun Ageing 2019; 16:19 CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males.
Br?ker K et al. Front Bioeng Biotechnol 2019; 7:194 Mass Production of Highly Active NK Cells for Cancer Immunotherapy in a GMP Conform Perfusion Bioreactor.
Acquaviva M et al. Front Immunol 2019; 10:1922 Loss of Circulating CD8+ CD161high T Cells in Primary Progressive Multiple Sclerosis.
Yousefi Z et al. Leuk Res Rep 2019; 12:100181 Prognostic significance of Fc receptor-like 1 in patients with chronic lymphocytic leukemia, hairy cell leukemia, and various B-cell non-Hodgkin's lymphoma.
Fox JJ et al. Am J Clin Exp Urol 2019; 7 (4):281-296 Mass cytometry reveals species-specific differences and a new level of complexity for immune cells in the prostate.
Wagstaffe HR et al. J Immunol 2019; 203 (6):1609-1618 Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and NK Cell Function.
Crawford LB et al. mBio 2019; 10 (4) Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34+ Hematopoietic Progenitor Cells and Humanized NSG Mice.
Ormh?j M et al. Clin Cancer Res 2019; 25 (23):7046-7057 Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19.
DeWolfe D et al. Front Immunol 2019; 10:1890 NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates.
Marquardt N et al. Nat Commun 2019; 10 (1):3841 Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.
Conde CD et al. J Clin Invest 2019; 129 (10):4194-4206 Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress.
Rasoulouniriana D et al. J Clin Invest 2019; 129 (10):4151-4164 A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Tauber C et al. Oncotarget 2019; 10 (50):5194-5206 Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma.
Apodaca MC et al. J Immunother Cancer 2019; 7 (1):230 Characterization of a whole blood assay for quantifying myeloid-derived suppressor cells.
Burbano C et al. Front Immunol 2019; 10:2058 Proinflammatory Differentiation of Macrophages Through Microparticles That Form Immune Complexes Leads to T- and B-Cell Activation in Systemic Autoimmune Diseases.
Yang C et al. Nat Commun 2019; 10 (1):3931 Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome.
Soon CF et al. Front Immunol 2019; 10:2076 Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy.
Gomez-Ospina N et al. Nat Commun 2019; 10 (1):4045 Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I.
Matsuyama H et al. Sci Rep 2019; 9 (1):13181 Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients.
Enqvist M et al. Front Immunol 2019; 10:2085 Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma.
Hashwah H et al. EMBO Mol Med 2019; 11 (10):e10576 The IL-6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B-cell lymphoma.
Naluyima P et al. J Immunol 2019; 203 (8):2210-2221 Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity.
Fajgenbaum DC et al. J Clin Invest 2019; 129 (10):4451-4463 Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.
Banerjee P et al. Cancer Immunol Res 2019; 7 (12):2036-2051 Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia.
Rodriguez R et al. J Exp Med 2019; 216 (12):2800-2818 Concomitant PIK3CD and TNFRSF9 deficiencies cause chronic active Epstein-Barr virus infection of T cells.
Carvelli J et al. Front Immunol 2019; 10:2179 Imbalance of Circulating Innate Lymphoid Cell Subpopulations in Patients With Septic Shock.
Branco ACCC et al. Sci Rep 2019; 9 (1):13721 Proinflammatory profile of neonatal monocytes induced by microbial ligands is downmodulated by histamine.
McLeod B et al. Nat Commun 2019; 10 (1):4328 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Kholodnyuk I et al. Medicina (Kaunas) 2019; 55 (10) Proportion of the CD19-Positive and CD19-Negative Lymphocytes and Monocytes within the Peripheral Blood Mononuclear Cell Set is Characteristic for Rheumatoid Arthritis.
Campi-Azevedo AC et al. Front Immunol 2019; 10:2192 Short-Lived Immunity After 17DD Yellow Fever Single Dose Indicates That Booster Vaccination May Be Required to Guarantee Protective Immunity in Children.
G?tzke H et al. Nat Commun 2019; 10 (1):4403 The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Beltr?n E et al. J Clin Invest 2019; 129 (11):4758-4768 Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis.
Bonne-Ann?e S et al. Sci Rep 2019; 9 (1):14305 Differential Modulation of Human Innate Lymphoid Cell (ILC) Subsets by IL-10 and TGF-β.
Caeser R et al. Nat Commun 2019; 10 (1):4543 Genetic modification of primary human B cells to model high-grade lymphoma.
Crisler WJ et al. Life Sci Alliance 2019; 2 (5) Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness.
Mastelic-Gavillet B et al. J Immunother Cancer 2019; 7 (1):257 Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells.
Agarwal S et al. Oncoimmunology 2019; 8 (12):e1671761 In vivo generated human CAR T cells eradicate tumor cells.
Smith C et al. J Clin Invest 2019; 129 (11):5020-5032 T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response.
Winklmeier S et al. Neurol Neuroimmunol Neuroinflamm 2019; 6 (6):625 Identification of circulating MOG-specific B cells in patients with MOG antibodies.
Bruggeman CW et al. PLoS One 2019; 14 (10):e0223264 Tissue-specific expression of IgG receptors by human macrophages ex vivo.
Henry C et al. J Virol 2019; 93 (21) Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study.
Stowe CL et al. Elife 2019; 8 Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin.
Bocharnikov AV et al. JCI Insight 2019; 4 (20) PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
Cantero-P?rez J et al. Nat Commun 2019; 10 (1):4739 Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa.
Wagenblast E et al. Nat Commun 2019; 10 (1):4730 Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells.
Meda Spaccamela V et al. Front Immunol 2019; 10:2236 High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease.
Swieboda D et al. Cytometry A 2019; 95 (12):1231-1235 OMIP-062: A 14-Color, 16-Antibody Panel for Immunophenotyping Human Innate Lymphoid, Myeloid and T Cells in Small Volumes of Whole Blood and Pediatric Airway Samples.
Le Gars M et al. Front Immunol 2019; 10:2469 Pregnancy-Induced Alterations in NK Cell Phenotype and Function.
Satta A et al. Front Immunol 2019; 10:2514 A Bispecific Antibody to Link a TRAIL-Based Antitumor Approach to Immunotherapy.
Ladinsky MS et al. Elife 2019; 8 Mechanisms of virus dissemination in bone marrow of HIV-1-infected humanized BLT mice.
Rivera-Mulia JC et al. Blood Adv 2019; 3 (21):3201-3213 Replication timing alterations in leukemia affect clinically relevant chromosome domains.
Mold JE et al. PLoS Biol 2019; 17 (10):e3000383 Cell generation dynamics underlying naive T-cell homeostasis in adult humans.
Burns DM et al. Front Immunol 2019; 10:2489 Non-uniform in vivo Expansion of Epstein-Barr Virus-Specific T-Cells Following Donor Lymphocyte Infusion for Post-transplant Lymphoproliferative Disease.
Giraldo-Villegas M et al. Future Sci OA 2019; 5 (10):FSO423 Polyacrylic acid-coated iron oxide nanoparticles could be a useful tool for tracking inflammatory monocytes.
Upasani V et al. Front Immunol 2019; 10:2500 Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.
Brown CC et al. Cell 2019; 179 (4):846-863.e24 Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Chen YY et al. JHEP Rep 2019; 1 (5):369-376 Intrahepatic macrophage populations in the pathophysiology of primary sclerosing cholangitis.
Escudero-P?rez B et al. JCI Insight 2019; 4 (21) Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice.
Shinko D et al. Front Immunol 2019; 10:2584 Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients.
Fuchs YF et al. Front Immunol 2019; 10:2568 Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level.
Tobin RP et al. Front Oncol 2019; 9:1223 IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients.
Onodera T et al. J Immunol 2019; 203 (12):3282-3292 Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.
Rivera-Correa J et al. Elife 2019; 8 Atypical memory B-cells are associated with Plasmodium falciparum anemia through anti-phosphatidylserine antibodies.
Waugh KA et al. Cell Rep 2019; 29 (7):1893-1908.e4 Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome.
Hashimoto K et al. Proc Natl Acad Sci U S A 2019; 116 (48):24242-24251 Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.
Auladell M et al. Clin Transl Immunology 2019; 8 (11):e01090 Distinguishing naive- from memory-derived human B cells during acute responses.
Kiani Z et al. J Virol 2019; 93 (23) The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells.
Pugh J et al. Life Sci Alliance 2019; 2 (6) In vitro education of human natural killer cells by KIR3DL1.
B?zie S et al. Blood Adv 2019; 3 (22):3522-3538 Human CD8+ Tregs expressing a MHC-specific CAR display enhanced suppression of human skin rejection and GVHD in NSG mice.
Carnero Contentti E et al. Front Immunol 2019; 10:2690 Mucosal-Associated Invariant T Cell Features and TCR Repertoire Characteristics During the Course of Multiple Sclerosis.
Sabatino JJ Jr et al. Proc Natl Acad Sci U S A 2019; 116 (51):25800-25807 Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis.
Messias CV et al. BMC Infect Dis 2019; 19 (1):986 Zika virus infects human blood mononuclear cells.
Hazenberg MD et al. Blood Adv 2019; 3 (22):3650-3660 Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease.
Gyurova IE et al. Front Immunol 2019; 10:2728 Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection.
Koenig A et al. Nat Commun 2019; 10 (1):5350 Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants.
Polito R et al. Front Immunol 2019; 10:2812 Adiponectin Receptors and Pro-inflammatory Cytokines Are Modulated in Common Variable Immunodeficiency Patients: Correlation With Ig Replacement Therapy.
Batalha IL et al. J Control Release 2019; 314:116-124 Polymeric nanobiotics as a novel treatment for mycobacterial infections.
Wada H et al. Sci Rep 2019; 9 (1):17981 Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
Pucino V et al. Cell Metab 2019; 30 (6):1055-1074.e8 Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring.
Heinze A et al. Front Immunol 2019; 10:2816 The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation.
M?ller J et al. JCI Insight 2019; 4 (23) Cytomegalovirus infection is a risk factor for tuberculosis disease in infants.
Kim KH et al. Front Immunol 2019; 10:2865 Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C.
Roper SI et al. Elife 2019; 8 B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments.
Herrera L et al. Sci Rep 2019; 9 (1):18729 Adult peripheral blood and umbilical cord blood NK cells are good sources for effective CAR therapy against CD19 positive leukemic cells.
Leylek R et al. Cell Rep 2019; 29 (11):3736-3750.e8 Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.
Urlaub D et al. Arthritis Res Ther 2019; 21 (1):277 Activation of natural killer cells by rituximab in granulomatosis with polyangiitis.
Jimeno R et al. Elife 2019; 8 Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.
Vaisman-Mentesh A et al. Front Immunol 2019; 10:2921 Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists.
Pilon C et al. Front Immunol 2019; 10:2908 Human Apoptotic Cells, Generated by Extracorporeal Photopheresis, Modulate Allogeneic Immune Response.
Lee WI et al. Front Immunol 2019; 10:2833 A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes.
Hurrell BP et al. Cell Rep 2019; 29 (13):4509-4524.e5 TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity.
Tian Y et al. Cell Rep 2019; 29 (13):4482-4495.e4 Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4?T Cells and Their Association with Dengue Disease.
Jiang L et al. J Immunol Res 2019; 2019:7914326 Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes.
M?ller S et al. Front Immunol 2019; 10:3123 High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia.
Meraz IM et al. Cancer Immunol Res 2019; 7 (8):1267-1279 An Improved Patient-Derived Xenograft Humanized Mouse Model for Evaluation of Lung Cancer Immune Responses.
Cossarizza A et al. Eur J Immunol 2019; 49 (10):1457-1973 Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Kinjyo I et al. J Leukoc Biol 2019; 105 (4):741-753 Leukemia-derived exosomes and cytokines pave the way for entry into the brain.
Nguyen S et al. Sci Transl Med 2019; 11 (523) Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells.
Calvanese V et al. Nature 2019; 576 (7786):281-286 MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment.
Aliprandini E et al. Toxicon X 2019; 2:100006 An oligoclonal combination of human monoclonal antibodies able to neutralize tetanus toxin in vivo.
Satpathy AT et al. Nat Biotechnol 2019; 37 (8):925-936 Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion.
Jordan S et al. Cell 2019; 178 (5):1102-1114.e17 Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.
Zappasodi R et al. Nat Med 2019; 25 (5):759-766 Rational design of anti-GITR-based combination immunotherapy.
Schulten V et al. J Allergy Clin Immunol 2018; 141 (2):775-777.e6 Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells.
Bogaert DJ et al. J Allergy Clin Immunol 2018; 141 (1):432-435.e7 A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.
den Hartog G et al. Eur J Immunol 2018; 48 (2):283-292 BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B?cells.
Moore T et al. Cancer Immunol Immunother 2018; 67 (2):311-325 Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Jenkins RW et al. Cancer Discov 2018; 8 (2):196-215 Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.
Renand A et al. J Allergy Clin Immunol 2018; 141 (5):1750-1760.e1 Synchronous immune alterations mirror clinical response during allergen immunotherapy.
Wang M et al. FASEB J 2018; 32 (3):1537-1549 Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Yaguchi T et al. Cell Mol Immunol 2018; 15 (11):953-962 Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses.
Khamaikawin W et al. Mol Ther Methods Clin Dev 2018; 9:23-32 Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1.
Mayer RL et al. Mol Cell Proteomics 2018; 17 (2):290-303 Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
Tsuda B et al. Breast Cancer 2018; 25 (3):284-291 B-cell populations are expanded in breast cancer patients compared with healthy controls.
Miller JS et al. Clin Cancer Res 2018; 24 (7):1525-1535 A First-in-Human Phase I Study of Subcutaneous Outpatient Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors.
Choi YS et al. Gastroenterology 2018; 154 (4):1047-1060 Tumor Necrosis Factor-producing T-regulatory Cells Are?Associated With Severe Liver Injury in Patients With Acute?Hepatitis A.
Keawvichit R et al. Immunology 2018; 153 (4):455-465 Differences in activation and tissue homing markers of natural killer cell subsets during acute dengue infection.
Amodio D et al. J Immunol 2018; 200 (2):538-550 Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination.
Han SS et al. Oncotarget 2018; 9 (3):3292-3302 BAFF and APRIL expression as an autoimmune signature of membranous nephropathy.
Chambers ES et al. Clin Exp Allergy 2018; 48 (1):13-22 Dendritic cell phenotype in severe asthma reflects clinical responsiveness to glucocorticoids.
Pugh JL et al. J Immunol 2018; 200 (3):1146-1158 Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage.
Hua S et al. Clin Infect Dis 2018; 66 (12):1910-1917 Pegylated Interferon-α-Induced Natural Killer Cell Activation Is Associated With Human Immunodeficiency Virus-1 DNA Decline in Antiretroviral Therapy-Treated HIV-1/Hepatitis C Virus-Coinfected Patients.
Rouha H et al. Virulence 2018; 9 (1):231-247 Disarming Staphylococcus aureus from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies.
Seang S et al. AIDS Res Hum Retroviruses 2018; 34 (1):39-45 Low Levels of Endothelial Progenitor Cells and Their Association with Systemic Inflammation and Monocyte Activation in Older HIV-Infected Men.
Fan Y et al. Biochem J 2018; 475 (1):23-44 Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.
Cao Q et al. J Am Soc Nephrol 2018; 29 (3):961-976 Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury.
Findlay JS et al. Viruses 2018; 10 (1) Blood Coagulation Factor X Exerts Differential Effects on Adenovirus Entry into Human Lymphocytes.
Wang B et al. Nat Biotechnol 2018; 36 (2):152-155 Functional interrogation and mining of natively paired human VH:VL antibody repertoires.
Winter S et al. EMBO Mol Med 2018; 10 (2):188-199 Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility.
Ritter M et al. PLoS Negl Trop Dis 2018; 12 (1):e0006184 Mansonella perstans microfilaremic individuals are characterized by enhanced type 2 helper T and regulatory T and B cell subsets and dampened systemic innate and adaptive immune responses.
Fink C et al. Sci Rep 2018; 8 (1):590 19F-perfluorocarbon-labeled human peripheral blood mononuclear cells can be detected in vivo using clinical MRI parameters in a therapeutic cell setting.
Li H et al. PLoS Genet 2018; 14 (1):e1007163 Identification of an elaborate NK-specific system regulating HLA-C expression.
Ng SS et al. Clin Transl Immunology 2018; 7 (1):e1003 Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.
McCarthy KR et al. Immunity 2018; 48 (1):174-184.e9 Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Hung CH et al. Sci Rep 2018; 8 (1):919 Altered pattern of monocyte differentiation and monocyte-derived TGF-β1 in severe asthma.
Arruda LCM et al. Blood Adv 2018; 2 (2):126-141 Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients.
Kornilov R et al. J Extracell Vesicles 2018; 7 (1):1422674 Efficient ultrafiltration-based protocol to deplete extracellular vesicles from fetal bovine serum.
Noyan K et al. Front Immunol 2018; 9:19 Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells.
Xu SX et al. PLoS One 2018; 13 (1):e0191672 Neisseria gonorrhoeae co-infection exacerbates vaginal HIV shedding without affecting systemic viral loads in human CD34+ engrafted mice.
Warner WA et al. Blood Adv 2018; 2 (2):151-163 Expression profiling of snoRNAs in normal hematopoiesis and AML.
Kiener R et al. Sci Rep 2018; 8 (1):1474 Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo.
Messlinger H et al. Front Immunol 2018; 9:24 Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites.
Johnston HE et al. Mol Cell Proteomics 2018; 17 (4):776-791 Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.
Bak RO et al. Nat Protoc 2018; 13 (2):358-376 CRISPR/Cas9 genome editing in human hematopoietic stem cells.
Guo B et al. Nat Med 2018; 24 (3):360-367 Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis.
Cepeda S et al. Cell Rep 2018; 22 (5):1276-1287 Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens.
Zeng H et al. Sci Adv 2018; 4 (1):eaar5701 Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Wong TN et al. Nat Commun 2018; 9 (1):455 Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.
Bujko A et al. J Exp Med 2018; 215 (2):441-458 Transcriptional and functional profiling defines human small intestinal macrophage subsets.
Hulsmans M et al. J Exp Med 2018; 215 (2):423-440 Cardiac macrophages promote diastolic dysfunction.
B?iers C et al. Dev Cell 2018; 44 (3):362-377.e7 A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B?Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Kagoya Y et al. Nat Med 2018; 24 (3):352-359 A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.
Mamedov MR et al. Immunity 2018; 48 (2):350-363.e7 A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
Kilinc MO et al. Clin Transl Med 2018; 7 (1):5 The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy.
Zhou J et al. Theranostics 2018; 8 (6):1575-1590 Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1.
Bill M et al. J Cell Mol Med 2018; 22 (4):2311-2318 Mapping the CLEC12A expression on myeloid progenitors in normal bone marrow; implications for understanding CLEC12A-related cancer stem cell biology.
Doi H et al. J Gastroenterol Hepatol 2018; Enhanced B-cell differentiation driven by advanced cirrhosis resulting in hyperglobulinemia.
Li C et al. Mol Ther Methods Clin Dev 2018; 9:142-152 Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies.
Zhou J et al. Toxicol Sci 2018; 163 (1):319-329 Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes.
Patas K et al. Front Immunol 2018; 9:291 T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder.
Lu N et al. Nat Commun 2018; 9 (1):742 Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4.
Zhang JQ et al. Cancer Immunol Res 2018; 6 (4):434-447 Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors.
Blum LK et al. Eur J Immunol 2018; 48 (5):874-884 Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.
Anderson J et al. Front Immunol 2018; 9:301 Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans.
Rius C et al. J Immunol 2018; 200 (7):2263-2279 Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Hansen IS et al. Nat Commun 2018; 9 (1):863 FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.
Oliveira ES et al. Viruses 2018; 10 (3) Increased Levels of Txa? Induced by Dengue Virus Infection in IgM Positive Individuals Is Related to the Mild Symptoms of Dengue.
Wagstaffe HR et al. J Immunol 2018; 200 (8):2738-2747 IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production.
Koreth J et al. Haematologica 2018; 103 (3):522-530 Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results.
Burbano C et al. Front Immunol 2018; 9:322 Potential Involvement of Platelet-Derived Microparticles and Microparticles Forming Immune Complexes during Monocyte Activation in Patients with Systemic Lupus Erythematosus.
Cerignoli F et al. PLoS One 2018; 13 (3):e0193498 In vitro immunotherapy potency assays using real-time cell analysis.
Gomez-Lopez N et al. Am J Reprod Immunol 2018; 79 (4):e12827 The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies.
Berin MC et al. J Allergy Clin Immunol 2018; 142 (1):149-158.e8 Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy.
Subrahmanyam PB et al. J Immunother Cancer 2018; 6 (1):18 Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients.
Niu J et al. Clin Exp Immunol 2018; 192 (2):206-212 Dissection of a circulating CD3+ CD20+ T cell subpopulation in patients with psoriasis.
Wetzels S et al. J Vis Exp 2018; (133) Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry.
Gherardin NA et al. Sci Rep 2018; 8 (1):4159 Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma.
Duggal NA et al. Aging Cell 2018; 17 (2) Major features of immunesenescence, including reduced thymic output, are ameliorated by high levels of physical activity in adulthood.
Gies V et al. JCI Insight 2018; 3 (5) Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.
Vanshylla K et al. Sci Rep 2018; 8 (1):4244 Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells.
Wun KS et al. Nat Immunol 2018; 19 (4):397-406 T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Toapanta FR et al. J Transl Med 2018; 16 (1):61 T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.
Germeshausen M et al. Blood Adv 2018; 2 (6):586-596 MECOM-associated syndrome: a heterogeneous inherited bone marrow failure syndrome with amegakaryocytic thrombocytopenia.
Satheesan S et al. J Virol 2018; 92 (7) HIV Replication and Latency in a Humanized NSG Mouse Model during Suppressive Oral Combinational Antiretroviral Therapy.
Cole C et al. Nucleic Acids Res 2018; 46 (10):e62 Tn5Prime, a Tn5 based 5' capture method for single cell RNA-seq.
Zheng S et al. Mol Syst Biol 2018; 14 (3):e8041 Molecular transitions in early progenitors during human cord blood hematopoiesis.
Ravens S et al. Front Immunol 2018; 9:510 Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy.
Publicover J et al. Sci Transl Med 2018; 10 (433) An OX40/OX40L interaction directs successful immunity to hepatitis B virus.
Motwani MP et al. JCI Insight 2018; 3 (6) Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.
Otta DA et al. Antimicrob Agents Chemother 2018; 62 (4) Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity.
Utzschneider DT et al. Cell Rep 2018; 22 (13):3454-3467 Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1.
Garc?a-Salum T et al. Oncotarget 2018; 9 (24):17014-17027 Molecular signatures associated with tumor-specific immune response in melanoma patients treated with dendritic cell-based immunotherapy.
Butler A et al. Nat Biotechnol 2018; 36 (5):411-420 Integrating single-cell transcriptomic data across different conditions, technologies, and species.
Hung CH et al. BMC Cancer 2018; 18 (1):366 Altered monocyte differentiation and macrophage polarization patterns in patients with breast cancer.
Panda SK et al. J Clin Invest 2018; 128 (5):1873-1887 Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.
Chen Q et al. Front Immunol 2018; 9:599 Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody.
Asano T et al. Front Immunol 2018; 9:568 Enhanced AKT Phosphorylation of Circulating B Cells in Patients With Activated PI3Kδ Syndrome.
Maehara T et al. Life Sci Alliance 2018; 1 (1) The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo.
Arce Vargas F et al. Cancer Cell 2018; 33 (4):649-663.e4 Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Kebir H et al. J Clin Invest 2018; 128 (5):2000-2009 Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis.
Gardner JK et al. PLoS One 2018; 13 (4):e0195313 Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.
Buggert M et al. PLoS Pathog 2018; 14 (4):e1006973 Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
He X et al. EMBO J 2018; 37 (11) Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
Surendran N et al. Innate Immun 2018; 24 (4):240-251 TLR agonist combinations that stimulate Th type I polarizing responses from human neonates.
Crawford LB et al. mBio 2018; 9 (2) Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation.
Roders N et al. Front Immunol 2018; 9:787 SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production.
Frascoli M et al. Sci Transl Med 2018; 10 (438) Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α.
Cheung P et al. Cell 2018; 173 (6):1385-1397.e14 Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging.
Heger L et al. Front Immunol 2018; 9:744 CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.
Lemarquis AL et al. Front Immunol 2018; 9:909 Transitional B Cells and TLR9 Responses Are Defective in Selective IgA Deficiency.
Van Nieuwenhove E et al. J Allergy Clin Immunol 2018; 142 (2):699-702.e12 A kindred with mutant IKAROS and autoimmunity.
Alhakeem SS et al. J Immunol 2018; 200 (12):4180-4189 Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity.
Li C et al. Mol Ther Methods Clin Dev 2018; 9:390-401 HDAd5/35++ Adenovirus Vector Expressing Anti-CRISPR Peptides Decreases CRISPR/Cas9 Toxicity in Human Hematopoietic Stem Cells.
Mielle J et al. Front Immunol 2018; 9:961 IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis.
Charlesworth CT et al. Mol Ther Nucleic Acids 2018; 12:89-104 Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting.
Verney A et al. Oncotarget 2018; 9 (34):23589-23598 Toll-like receptor expression and function differ between splenic marginal zone B cell lymphoma and splenic diffuse red pulp B cell lymphoma.
Murray LW et al. J Infect Dis 2018; 217 (11):1782-1792 Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis-Specific T-Cell Responses.
Rajasekhar M et al. Sci Rep 2018; 8 (1):7264 Identifying microRNA determinants of human myelopoiesis.
Cooles FAH et al. Front Immunol 2018; 9:755 Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Na?ve Rheumatoid Arthritis.
Huang H et al. Clin Immunol 2018; 193:1-9 23-valent pneumococcal polysaccharide vaccine elicits hierarchical antibody and cellular responses in healthy and tuberculosis-cured elderly, and HIV-1-infected subjects.
Heukels P et al. Respir Res 2018; 19 (1):90 Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis.
Shinde R et al. Nat Immunol 2018; 19 (6):571-582 Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Risnes LF et al. J Clin Invest 2018; 128 (6):2642-2650 Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease.
Hill DA et al. Proc Natl Acad Sci U S A 2018; 115 (22):E5096-E5105 Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue.
Kagoya Y et al. Nat Commun 2018; 9 (1):1915 DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models.
Bengsch B et al. Immunity 2018; 48 (5):1029-1045.e5 Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8?T Cells.
Zhong J et al. Sci Adv 2018; 4 (5):eaas9864 Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes.
Vogt MB et al. PLoS Negl Trop Dis 2018; 12 (5):e0006439 Mosquito saliva alone has profound effects on the human immune system.
Garc?a-Peydr? M et al. J Clin Invest 2018; 128 (7):2802-2818 The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model.
Frobel J et al. Clin Epigenetics 2018; 10:67 Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice.
Kaur S et al. Front Physiol 2018; 9:556 Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis.
Abolhalaj M et al. Sci Rep 2018; 8 (1):8030 Profiling dendritic cell subsets in head and neck squamous cell tonsillar cancer and benign tonsils.
Iwabuchi R et al. Front Immunol 2018; 9:1042 Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells.
Wallin EF et al. Front Immunol 2018; 9:1184 The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells.
Young PA et al. J Interferon Cytokine Res 2018; 38 (6):239-254 Activity of Anti-CD19 Chimeric Antigen Receptor T Cells Against B Cell Lymphoma Is Enhanced by Antibody-Targeted Interferon-Alpha.
Antonarakis ES et al. Clin Cancer Res 2018; 24 (19):4662-4671 Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival.
Balasubramaniam S et al. Anticancer Drugs 2018; 29 (5):457-465
Lingblom CMD et al. J Transl Med 2018; 16 (1):153 Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults.
Laverdi?re I et al. Blood Cancer J 2018; 8 (6):52 Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia.
Costa-Pereira C et al. PLoS Negl Trop Dis 2018; 12 (6):e0006462 Multi-parameter approach to evaluate the timing of memory status after 17DD-YF primary vaccination.
Waight JD et al. Cancer Cell 2018; 33 (6):1033-1047.e5 Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T?Cell Antigens.
Zappasodi R et al. Cancer Cell 2018; 33 (6):1017-1032.e7 Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Setliff I et al. Cell Host Microbe 2018; 23 (6):845-854.e6 Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.
Perico N et al. Front Immunol 2018; 9:1359 Long-Term Clinical and Immunological Profile of Kidney Transplant Patients Given Mesenchymal Stromal Cell Immunotherapy.
Frey-Jakobs S et al. Sci Immunol 2018; 3 (24) ZNF341 controls STAT3 expression and thereby immunocompetence.
Haltaufderhyde K et al. J Infect Dis 2018; 218 (10):1675-1685 Activation of Peripheral T Follicular Helper Cells During Acute Dengue Virus Infection.
Moysi E et al. J Clin Invest 2018; 128 (7):3171-3185 Altered immune cell follicular dynamics in HIV infection following influenza vaccination.
Bluhm J et al. Mol Ther 2018; 26 (8):1906-1920 CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma.
Hirota K et al. Immunity 2018; 48 (6):1220-1232.e5 Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Kirkling ME et al. Cell Rep 2018; 23 (12):3658-3672.e6 Notch Signaling Facilitates In?Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Friedensohn S et al. Front Immunol 2018; 9:1401 Synthetic Standards Combined With Error and Bias Correction Improve the Accuracy and Quantitative Resolution of Antibody Repertoire Sequencing in Human Na?ve and Memory B Cells.
Piper CJM et al. Front Immunol 2018; 9:1372 CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.
Zhang Y et al. Front Cell Neurosci 2018; 12:170 Association Between Programed Cell Death-1 and CD4+ T Cell Alterations in Different Phases of Ischemic Stroke Patients.
Porichis F et al. J Immunol 2018; 201 (3):971-981 Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.
Renand A et al. Front Immunol 2018; 9:1408 Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects.
Chu C et al. Cell Rep 2018; 23 (13):3750-3758 Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183.
Miggelbrink AM et al. Blood 2018; 131 (26):2967-2977 B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation.
Dolton G et al. Front Immunol 2018; 9:1378 Optimized Peptide-MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells.
Rosenfeld AM et al. Front Immunol 2018; 9:1472 Computational Evaluation of B-Cell Clone Sizes in Bulk Populations.
Lawless D et al. Front Immunol 2018; 9:1527 A Case of Adult-Onset Still's Disease Caused by a Novel Splicing Mutation in TNFAIP3 Successfully Treated With Tocilizumab.
Rossetti RAM et al. PLoS One 2018; 13 (7):e0199034 B lymphocytes can be activated to act as antigen presenting cells to promote anti-tumor responses.
Duggal NA et al. Sci Rep 2018; 8 (1):10186 Innate and adaptive immune dysregulation in critically ill ICU patients.
Ngom M et al. Mol Ther Methods Clin Dev 2018; 10:156-164 UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells.
Zhao M et al. Nat Commun 2018; 9 (1):2627 Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.
Yarzabek B et al. Elife 2018; 7 Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity.
Amici SA et al. Front Immunol 2018; 9:1593 CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions.
Donlin LT et al. Arthritis Res Ther 2018; 20 (1):139 Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
Lertjuthaporn S et al. PLoS One 2018; 13 (7):e0200564 Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection.
Hu Y et al. Arthritis Rheumatol 2018; 70 (8):1331-1342 Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids.
Kim L et al. JCI Insight 2018; 3 (13) Safety and immunogenicity of an oral tablet norovirus vaccine, a phase I randomized, placebo-controlled trial.
Tasaki S et al. Nat Commun 2018; 9 (1):2755 Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.
Huang X et al. Nat Commun 2018; 9 (1):2741 Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment.
Yeo L et al. J Clin Invest 2018; 128 (8):3460-3474 Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes.
Kiener R et al. J Virol 2018; 92 (15) Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors.
Tanaka K et al. Oncotarget 2018; 9 (55):30587-30593 Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade.
Blum LK et al. Front Immunol 2018; 9:1634 Robust B Cell Responses Predict Rapid Resolution of Lyme Disease.
Hirata F et al. Ann Gastroenterol Surg 2018; 2 (5):383-393 Effect of bevacizumab plus XELOX (CapeOX) chemotherapy on liver natural killer cell activity in colorectal cancer with resectable liver metastasis.
Salzberger W et al. PLoS One 2018; 13 (7):e0201170 Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71.
Stein J et al. Front Neurol 2018; 9:554 Intrathecal B Cells in MS Have Significantly Greater Lymphangiogenic Potential Compared to B Cells Derived From Non-MS Subjects.
Kim ST et al. J Immunol 2018; 201 (5):1359-1372 Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs.
Tarique M et al. Front Immunol 2018; 9:1636 Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25- Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy.
Li M et al. PLoS One 2018; 13 (7):e0200478 Dengue immune sera enhance Zika virus infection in human peripheral blood monocytes through Fc gamma receptors.
Heshmati Y et al. Sci Rep 2018; 8 (1):11202 The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation.
Margolin K et al. Clin Cancer Res 2018; 24 (22):5552-5561 Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors.
Mieczkowska A et al. Sci Rep 2018; 8 (1):11339 Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells.
Achita P et al. Clin Exp Immunol 2018; 193 (3):386-399 Infusion of ex-vivo expanded human TCR-αβ+ double-negative regulatory T cells delays onset of xenogeneic graft-versus-host disease.
Bowyer G et al. Vaccines (Basel) 2018; 6 (3) Activation-induced Markers Detect Vaccine-Specific CD4? T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials.
Robinson HR et al. Blood 2018; 132 (5):521-532 A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.
Seo GY et al. Cell Host Microbe 2018; 24 (2):249-260.e4 LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection.
Otsuki N et al. PLoS One 2018; 13 (8):e0201764 A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein.
Psatha N et al. Mol Ther Methods Clin Dev 2018; 10:313-326 Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major.
Tobin RP et al. Int Immunopharmacol 2018; 63:282-291 Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab.
Kong XF et al. Nat Immunol 2018; 19 (9):973-985 Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.
Bajor DL et al. Oncoimmunology 2018; 7 (10):e1468956 Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.
Salter AI et al. Sci Signal 2018; 11 (544) Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.
Zhu YP et al. Cell Rep 2018; 24 (9):2329-2341.e8 Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow.
Agarwal D et al. Immun Ageing 2018; 15:19 Immune response to influenza vaccination in the elderly is altered by chronic medication use.
Yamaguchi K et al. Cancer Sci 2018; 109 (10):3032-3042 Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody.
Dam EM et al. Front Immunol 2018; 9:1978 Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.
Backes CS et al. J Biol Chem 2018; 293 (42):16348-16363 Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms.
Habets THPM et al. PLoS One 2018; 13 (9):e0203381 The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression.
Hamilton JA et al. J Immunol 2018; 201 (8):2203-2208 Cutting Edge: Intracellular IFN-β and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.
Aschenbrenner D et al. Nat Immunol 2018; 19 (10):1126-1136 An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells.
Nam HW et al. Clin Exp Immunol 2018; 194 (1):125-136 Functional status of immune cells in patients with long-lasting type 2 diabetes mellitus.
Lundy SK et al. Front Med (Lausanne) 2018; 5:249 T Helper 1 Cellular Immunity Toward Recoverin Is Enhanced in Patients With Active Autoimmune Retinopathy.
Jelcic I et al. Cell 2018; 175 (1):85-100.e23 Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis.
Chan CKF et al. Cell 2018; 175 (1):43-56.e21 Identification of the Human Skeletal Stem Cell.
James NE et al. Clin Exp Immunol 2018; 193 (3):327-340 HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells.
Sung JA et al. Mol Ther 2018; 26 (10):2496-2506 HIV-Specific, Ex?Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.
Noto A et al. J Virol 2018; 92 (20) CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.
Nakano M et al. Cancer Sci 2018; 109 (11):3461-3470 Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer.
Zacca ER et al. Front Immunol 2018; 9:2241 PD-L1+ Regulatory B Cells Are Significantly Decreased in Rheumatoid Arthritis Patients and Increase After Successful Treatment.
Ruella M et al. Nat Med 2018; 24 (10):1499-1503 Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.
Smith CC et al. J Clin Invest 2018; 128 (11):4804-4820 Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.
Shan M et al. Immunity 2018; 49 (4):709-724.e8 Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.
Bradley T et al. Cell 2018; 175 (2):387-399.e17 RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Poe JC et al. JCI Insight 2018; 3 (19) SYK inhibitor entospletinib prevents ocular and skin GVHD in mice.
Belluschi S et al. Nat Commun 2018; 9 (1):4100 Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors.
Zhang W et al. Drug Des Devel Ther 2018; 12:3343-3356 Characterization of clinical grade CD19 chimeric antigen receptor T cells produced using automated CliniMACS Prodigy system.
Meurer T et al. Front Immunol 2018; 9:2236 Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation.
Rotolo A et al. Cancer Cell 2018; 34 (4):596-610.e11 Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting.
Chow KT et al. J Immunol 2018; 201 (10):3036-3050 Differential and Overlapping Immune Programs Regulated by IRF3 and IRF5 in Plasmacytoid Dendritic Cells.
Zissler UM et al. EBioMedicine 2018; 36:475-488 Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT.
Garc?a-Rubio J et al. Sci Rep 2018; 8 (1):15203 Cytometric analysis of adipose tissue reveals increments of adipocyte progenitor cells after weight loss induced by bariatric surgery.
Otsuka Y et al. J Immunol 2018; 201 (10):3006-3016 Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells.
Lagou V et al. Cell Rep 2018; 25 (3):798-810.e6 Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.
Deng M et al. Nature 2018; 562 (7728):605-609 LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.
Annunziata P et al. Sci Rep 2018; 8 (1):15371 Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients.
Moreira D et al. Clin Cancer Res 2018; 24 (23):5948-5962 STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Kaur S et al. Sci Rep 2018; 8 (1):15503 Small non-coding RNA landscape of extracellular vesicles from human stem cells.
Skovdahl HK et al. Int J Mol Sci 2018; 19 (10) C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.
Elliott SE et al. Arthritis Rheumatol 2018; 70 (12):1946-1958 Affinity Maturation Drives Epitope Spreading and Generation of Proinflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.
Cheng WC et al. Clin Exp Immunol 2018; 194 (3):380-390 Comparative analysis of immune cell subsets in peripheral blood from patients with periodontal disease and healthy controls.
Harms RZ et al. Front Immunol 2018; 9:2332 Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.
Agrawal N et al. Front Immunol 2018; 9:2417 Human Monocytic Suppressive Cells Promote Replication of Mycobacterium tuberculosis and Alter Stability of in vitro Generated Granulomas.
Belarif L et al. Nat Commun 2018; 9 (1):4483 IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.
Summerauer AM et al. Malar J 2018; 17 (1):395 High purity high yield tandem B and T helper cell isolation for qRT-PCR analysis suitable for basically equipped laboratories.
Knier B et al. Nat Immunol 2018; 19 (12):1341-1351 Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
Yen J et al. Sci Rep 2018; 8 (1):16304 TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells.
Shastri A et al. J Clin Invest 2018; 128 (12):5479-5488 Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells.
Olson GS et al. Sci Rep 2018; 8 (1):16471 Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load.
Rodrigues-Santos P et al. Front Immunol 2018; 9:2587 Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors.
Leibler C et al. J Clin Med 2018; 7 (11) Rituximab and Fibrillary Glomerulonephritis: Interest of B Cell Reconstitution Monitoring.
Saraiva DP et al. Front Immunol 2018; 9:2605 HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy.
Savage TM et al. JCI Insight 2018; 3 (22) Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.
Barruet E et al. JCI Insight 2018; 3 (22) NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification.
Rathore DK et al. PLoS One 2018; 13 (11):e0207297 Differences in multiple immune parameters between Indian and U.S. infants.
Delcroix M et al. Pathog Dis 2018; 76 (8) Flow-cytometric analysis of human monocyte subsets targeted by Mycobacterium bovis BCG before granuloma formation.
Joo EJ et al. Sci Rep 2018; 8 (1):17174 Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein.
Kuri-Maga?a H et al. Front Immunol 2018; 9:2679 Non-coding Class Switch Recombination-Related Transcription in Human Normal and Pathological Immune Responses.
Mukherjee N et al. Oncotarget 2018; 9 (92):36492-36502 Intratumoral CD56bright natural killer cells are associated with improved survival in bladder cancer.
Pu X et al. J Transl Med 2018; 16 (1):328 Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer.
Osorio FG et al. Cell Rep 2018; 25 (9):2308-2316.e4 Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis.
Douam F et al. Nat Commun 2018; 9 (1):5031 Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.
Baglaenko Y et al. Arthritis Res Ther 2018; 20 (1):264 The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease.
Ott CJ et al. Cancer Cell 2018; 34 (6):982-995.e7 Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia.
Chee J et al. BMC Res Notes 2018; 11 (1):864 Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors.
Magill L et al. Front Immunol 2018; 9:2865 Low Percentage of Signal Regulatory Protein α/β+ Memory B Cells in Blood Predicts Development of Anti-drug Antibodies (ADA) in Adalimumab-Treated Rheumatoid Arthritis Patients.
van Zyl DG et al. PLoS Pathog 2018; 14 (12):e1007464 Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.
Tran HTT et al. Front Immunol 2018; 9:2949 Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes.
Castellanos JG et al. Immunity 2018; 49 (6):1077-1089.e5 Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.
Lee SY et al. Front Immunol 2018; 9:2881 The Therapeutic Effect of STAT3 Signaling-Suppressed MSC on Pain and Articular Cartilage Damage in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis.
Burbano C et al. Sci Rep 2018; 8 (1):17917 Extracellular vesicles are associated with the systemic inflammation of patients with seropositive rheumatoid arthritis.
He W et al. Immunity 2018; 49 (6):1175-1190.e7 Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues.
Kwon M et al. Immune Netw 2018; 18 (6):e45 Two-Round Mixed Lymphocyte Reaction for Evaluation of the Functional Activities of Anti-PD-1 and Immunomodulators.
Skibinski DAG et al. Sci Rep 2018; 8 (1):18007 Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine.
Bhaumik SK et al. Viruses 2018; 11 (1) Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
Passos LSA et al. Front Immunol 2018; 9:3015 Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease.
Fergusson JR et al. Front Immunol 2018; 9:2902 Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.
Hood SP et al. Front Immunol 2018; 9:3169 Phenotype and Function of Activated Natural Killer Cells From Patients With Prostate Cancer: Patient-Dependent Responses to Priming and IL-2 Activation.
Tomiyama T et al. Cell Mol Immunol 2017; 14 (3):276-284 The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis.
Selb R et al. J Allergy Clin Immunol 2017; 139 (1):290-299.e4 CD23 surface density on B?cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T?cells.
Burton OT et al. J Allergy Clin Immunol 2017; 139 (1):314-322.e9 A humanized mouse model of anaphylactic peanut allergy.
Bharadwaj AS et al. Ocul Immunol Inflamm 2017; 25 (6):811-819 Molecular Signals Involved in Human B Cell Migration into the Retina: In Vitro Investigation of ICAM-1, VCAM-1, and CXCL13.
Wege AK et al. Oncotarget 2017; 8 (2):2731-2744 IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM).
Svoronos N et al. Cancer Discov 2017; 7 (1):72-85 Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
Peperzak V et al. Cell Death Differ 2017; 24 (1):111-119 Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling.
Svensson A et al. J Neurooncol 2017; 131 (2):245-254 Identification of two distinct mesenchymal stromal cell populations in human malignant glioma.
Sierzega M et al. Ann Surg Oncol 2017; 24 (3):808-815 Preoperative Neutrophil-Lymphocyte and Lymphocyte-Monocyte Ratios Reflect Immune Cell Population Rearrangement in Resectable Pancreatic Cancer.
Fenton TM et al. Mucosal Immunol 2017; 10 (3):624-634 Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8.
Li X et al. Expert Rev Vaccines 2017; 16 (1):73-80 A potent adjuvant effect of a CD1d-binding NKT cell ligand in human immune system mice.
Achard C et al. Oncoimmunology 2017; 6 (1):e1261240 Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells.
Gosselin A et al. AIDS 2017; 31 (1):35-48 HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy.
Jab?o?ski M et al. Stem Cell Rev Rep 2017; 13 (2):217-225 Mobilization of Peripheral Blood Stem Cells and Changes in the Concentration of Plasma Factors Influencing their Movement in Patients with Panic Disorder.
Michels AW et al. Diabetes 2017; 66 (3):722-734 Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Spitsin S et al. J Leukoc Biol 2017; 101 (4):967-973 Substance P-mediated chemokine production promotes monocyte migration.
Huang B et al. Nat Med 2017; 23 (1):128-135 Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor.
Lu Z et al. Nat Med 2017; 23 (1):79-90 Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.
Cheeseman HM et al. J Virol 2017; 91 (1) Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies.
Baughn LB et al. Leuk Lymphoma 2017; 58 (8):1931-1940 Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry.
Hasan S et al. Am J Physiol Cell Physiol 2017; 312 (3):C286-C301 Myelo-erythroid commitment after burn injury is under β-adrenergic control via MafB regulation.
Rodr?guez-Carrio J et al. Arthritis Rheumatol 2017; 69 (1):70-76 Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At-Risk and Earliest Phases of Rheumatoid Arthritis.
Li J et al. Toxicology 2017; 378:17-24 Aryl hydrocarbon receptor activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs human B lymphopoiesis.
Nicholas KJ et al. J Acquir Immune Defic Syndr 2017; 74 (1):72-80 Chronic HIV-1 Infection Impairs Superantigen-Induced Activation of Peripheral CD4+CXCR5+PD-1+ Cells, With Relative Preservation of Recall Antigen-Specific Responses.
Kalampokis I et al. Arthritis Rheumatol 2017; 69 (1):225-238 The Regulatory B Cell Compartment Expands Transiently During Childhood and Is Contracted in Children With Autoimmunity.
Izawa K et al. J Exp Med 2017; 214 (1):73-89 Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection.
Tsuchida Y et al. PLoS One 2017; 12 (1):e0169646 TGF-β3 Inhibits Antibody Production by Human B Cells.
Dalli J et al. Immunity 2017; 46 (1):92-105 Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution.
Maetzig T et al. Mol Ther 2017; 25 (3):606-620 A Lentiviral Fluorescent Genetic Barcoding System for Flow Cytometry-Based Multiplex Tracking.
Guo A et al. Oncotarget 2017; 8 (8):12953-12967 Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment.
Hale M et al. Mol Ther Methods Clin Dev 2017; 4:192-203 Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells.
Chao MP et al. Cell Stem Cell 2017; 20 (3):329-344.e7 Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Tauriainen J et al. Sci Rep 2017; 7:40354 Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
Vander Heiden JA et al. J Immunol 2017; 198 (4):1460-1473 Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.
Beyer AI et al. Stem Cells Dev 2017; 26 (2):102-112 Comparison of Human Hematopoietic Reconstitution in Different Strains of Immunodeficient Mice.
Aw Yeang HX et al. J Immunol 2017; 198 (4):1417-1422 Cutting Edge: Human CD49e- NK Cells Are Tissue Resident in the Liver.
Williams CR et al. BMC Bioinformatics 2017; 18 (1):38 Empirical assessment of analysis workflows for differential expression analysis of human samples using RNA-Seq.
Hector SM et al. Clin Ophthalmol 2017; 11:179-184 Circulating monocytes and B-lymphocytes in neovascular age-related macular degeneration.
Baratella M et al. PLoS Negl Trop Dis 2017; 11 (1):e0005285 Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
Liu X et al. Genome Biol 2017; 18 (1):4 Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus.
Aravena O et al. Arthritis Res Ther 2017; 19 (1):8 TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients.
Aagaard KM et al. Sci Rep 2017; 7:41389 Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication.
Calderon TM et al. J Neuroimmune Pharmacol 2017; 12 (2):353-370 Dopamine Increases CD14+CD16+ Monocyte Transmigration across the Blood Brain Barrier: Implications for Substance Abuse and HIV Neuropathogenesis.
O'Connor D et al. Genome Med 2017; 9 (1):11 High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.
Thobakgale C et al. J Acquir Immune Defic Syndr 2017; 74 (2):213-220 Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients.
Rao DA et al. Nature 2017; 542 (7639):110-114 Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Sharma M et al. Indian J Med Res 2017; 145 (2):215-221 Haematological profile of patients with mixed-phenotype acute leukaemia from a tertiary care centre of north India.
Kadi? E et al. BMC Immunol 2017; 18 (1):6 Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis.
Riedel JH et al. J Am Soc Nephrol 2017; 28 (7):2068-2080 IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis.
Crome SQ et al. Nat Med 2017; 23 (3):368-375 A distinct innate lymphoid cell population regulates tumor-associated T cells.
Picarda E et al. JCI Insight 2017; 2 (3):e90088 Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.
Smulski CR et al. Cell Death Dis 2017; 8 (2):e2601 Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling.
Yi JS et al. Front Neurol 2017; 8:34 B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity.
Pereira I et al. Front Pharmacol 2017; 8:53 Transient Receptor Potential Ankyrin 1 Channel Expression on Peripheral Blood Leukocytes from Rheumatoid Arthritic Patients and Correlation with Pain and Disability.
Angelo MA et al. J Virol 2017; 91 (5) Human CD4+ T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.
Shikhagaie MM et al. Cell Rep 2017; 18 (7):1761-1773 Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates.
Moy RH et al. Blood 2017; 129 (7):906-916 Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis.
Spencer DH et al. Cell 2017; 168 (5):801-816.e13 CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Requena P et al. Front Immunol 2017; 8:163 Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study.
Ryzhov S et al. Am J Physiol Heart Circ Physiol 2017; 312 (5):H907-H918 ERBB signaling attenuates proinflammatory activation of nonclassical monocytes.
Chaturvedi A et al. Leukemia 2017; 31 (10):2020-2028 Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.
Flerin NC et al. J Virol 2017; 91 (6) T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.
Fresnay S et al. Front Immunol 2017; 8:208 Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model.
Corleis B et al. PLoS One 2017; 12 (3):e0173161 Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection.
Guo B et al. Nat Med 2017; 23 (4):424-428 Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment.
Esteve-Sol? A et al. Front Immunol 2017; 8:201 Characterization of the Highly Prevalent Regulatory CD24hiCD38hi B-Cell Population in Human Cord Blood.
Fischer K et al. Front Immunol 2017; 8:202 The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells.
Hoff P et al. Int J Mol Sci 2017; 18 (3) A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
Collins A et al. JCI Insight 2017; 2 (5):e90063 Eomesodermin and T-bet mark developmentally distinct human natural killer cells.
Singh AK et al. Front Immunol 2017; 8:260 High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis.
Effner R et al. Sci Rep 2017; 7:44005 Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.
Souza-Fonseca-Guimaraes P et al. Int J Mol Sci 2017; 18 (3) Natural Killer Cell Assessment in Peripheral Circulation and Bronchoalveolar Lavage Fluid of Patients with Severe Sepsis: A Case Control Study.
Higdon LE et al. Am J Transplant 2017; 17 (8):2045-2054 Cytomegalovirus-Responsive CD8+ T Cells Expand After Solid Organ Transplantation in the Absence of CMV Disease.
Paris RM et al. Pathog Immun 2017; 2 (1):66-88 Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection.
Fuchs YF et al. Sci Rep 2017; 7:44661 CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
Lu X et al. Nature 2017; 543 (7647):728-732 Effective combinatorial immunotherapy for castration-resistant prostate cancer.
Tsoneva D et al. Mol Ther Oncolytics 2017; 5:41-61 Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis.
Seong Y et al. JCI Insight 2017; 2 (6):e90233 Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge.
Nouri-Shirazi M et al. BMC Vet Res 2017; 13 (1):78 Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care.
Hamada S et al. Open J Immunol 2017; 7 (1):1-17 Soluble MICB in Plasma and Urine Explains Population Expansions of NKG2D+CD4 T Cells Inpatients with Juvenile-Onset Systemic Lupus Erythematosus.
Collins PJ et al. FASEB J 2017; 31 (7):3084-3097 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.
Camelo A et al. Blood Adv 2017; 1 (10):577-589 IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells.
Lopes FB et al. J Cell Biol 2017; 216 (4):1123-1141 Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages.
Dallari S et al. Nat Commun 2017; 8:14830 Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses.
West NR et al. Nat Med 2017; 23 (5):579-589 Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
Seet CS et al. Nat Methods 2017; 14 (5):521-530 Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids.
Lima JF et al. Sci Rep 2017; 7 (1):524 Polyfunctional natural killer cells with a low activation profile in response to Toll-like receptor 3 activation in HIV-1-exposed seronegative subjects.
Bruce DW et al. J Clin Invest 2017; 127 (5):1813-1825 Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease.
Gies V et al. Sci Rep 2017; 7 (1):602 Identification of autoreactive B cells with labeled nucleosomes.
Zheng Q et al. Mol Oncol 2017; 11 (5):584-594 Diphtheria toxin-based anti-human CD19 immunotoxin for targeting human CD19+ tumors.
Nevala WK et al. Sci Rep 2017; 7:45682
Salerno-Goncalves R et al. Front Immunol 2017; 8:398 Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells.
Rupp LJ et al. Sci Rep 2017; 7 (1):737 CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.
M?ller MM et al. Sci Rep 2017; 7 (1):838 Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression.
Chassaing B et al. Cell Mol Gastroenterol Hepatol 2017; 4 (2):205-221 Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans.
Deng C et al. J Diabetes Res 2017; 2017:5052812 The Imbalance of B-Lymphocyte Subsets in Subjects with Different Glucose Tolerance: Relationship with Metabolic Parameter and Disease Status.
Cottineau J et al. J Clin Invest 2017; 127 (5):1991-2006 Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.
Linedale R et al. PLoS One 2017; 12 (4):e0175755 Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients.
Knox JJ et al. JCI Insight 2017; 2 (8) T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.
Adamczyk A et al. JCI Insight 2017; 2 (8) Differential expression of GPR15 on T cells during ulcerative colitis.
Crawford LB et al. Sci Rep 2017; 7 (1):937 Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.
Xu Y et al. Front Immunol 2017; 8:376 HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells.
Vladimer GI et al. Nat Chem Biol 2017; 13 (6):681-690 Global survey of the immunomodulatory potential of common drugs.
Darboe A et al. Eur J Immunol 2017; 47 (6):1040-1050 Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans.
Yang D et al. Sci Rep 2017; 7 (1):1288 NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus.
Manion M et al. PLoS One 2017; 12 (5):e0175517 Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons.
Pryke KM et al. mBio 2017; 8 (3) A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.
Eitan E et al. Sci Rep 2017; 7 (1):1342 Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes.
Schoenhals M et al. Cell Cycle 2017; 16 (11):1104-1117 Hypoxia favors the generation of human plasma cells.
Wieland D et al. Nat Commun 2017; 8:15050 TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.
Budde H et al. Cent Eur J Immunol 2017; 42 (1):1-9 In vitro effects of different 8-methoxypsoralen treatment protocols for extracorporeal photopheresis on mononuclear cells.
Lord JD et al. World J Gastroenterol 2017; 23 (18):3240-3251 Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease.
Nakachi S et al. Arthritis Res Ther 2017; 19 (1):97 Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.
Cale EM et al. Immunity 2017; 46 (5):777-791.e10 Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Euteneuer F et al. Transl Psychiatry 2017; 7 (5):e1132 Immunological effects of behavioral activation with exercise in major depression: an exploratory randomized controlled trial.
Xu L et al. Mol Ther 2017; 25 (8):1782-1789 CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In?Vivo.
Sugimura R et al. Nature 2017; 545 (7655):432-438 Haematopoietic stem and progenitor cells from human pluripotent stem cells.
Sharma M et al. Sci Rep 2017; 7 (1):2085 Inhibition of endocytic lipid antigen presentation by common lipophilic environmental pollutants.
Penatti A et al. Arthritis Res Ther 2017; 19 (1):103 Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis.
Afzali B et al. Nat Immunol 2017; 18 (7):813-823 BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.
Sandri S et al. Oncotarget 2017; 8 (50):86987-87001 Effective control of acute myeloid leukaemia and acute lymphoblastic leukaemia progression by telomerase specific adoptive T-cell therapy.
Chapel A et al. Sci Rep 2017; 7 (1):2414 Peptide-specific engagement of the activating NK cell receptor KIR2DS1.
Vujkovic-Cvijin I et al. Gut Microbes 2017; 8 (5):440-450 Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals.
Jones AP et al. Clin Transl Immunology 2017; 6 (5):e143 Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis.
Shoda H et al. Arthritis Res Ther 2017; 19 (1):111 Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis.
Cerosaletti K et al. J Immunol 2017; 199 (1):323-335 Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
Vo TT et al. Mol Cancer Ther 2017; 16 (9):1942-1953 mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph+ and Ph-like B-ALL.
Loughland JR et al. Sci Rep 2017; 7 (1):2596 Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation.
Matsuoka Y et al. Cell Transplant 2017; 26 (6):1043-1058 CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells.
Cerboni S et al. J Exp Med 2017; 214 (6):1769-1785 Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.
Karnell FG et al. Clin Exp Immunol 2017; 189 (3):268-278 Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation.
Marcial GE et al. Front Immunol 2017; 8:655 Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults.
Wagner J et al. Front Immunol 2017; 8:676 A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma.
Rolland DCM et al. Proc Natl Acad Sci U S A 2017; 114 (25):6581-6586 Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas.
Yu M et al. Sci Rep 2017; 7 (1):3350 Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis.
Moguche AO et al. Cell Host Microbe 2017; 21 (6):695-706.e5 Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.
Cho A et al. JCI Insight 2017; 2 (12) Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab.
McDonnell AM et al. BMC Cancer 2017; 17 (1):417 Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters.
Trend S et al. Int J Mol Sci 2017; 18 (6) Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI.
M?tayer LE et al. Oncotarget 2017; 8 (37):60892-60903 Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis.
Ganesan AP et al. Nat Immunol 2017; 18 (8):940-950 Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer.
Jourdan M et al. PLoS One 2017; 12 (6):e0179793 Characterization of human FCRL4-positive B cells.
Sulzer D et al. Nature 2017; 546 (7660):656-661 T cells from patients with Parkinson's disease recognize α-synuclein peptides.
Buranapraditkun S et al. J Virol 2017; 91 (14) Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers.
Lee J et al. Nat Immunol 2017; 18 (8):877-888 Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors.
Jiang X et al. Front Immunol 2017; 8:765 Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation.
Rutishauser RL et al. AIDS Res Hum Retroviruses 2017; 33 (7):658-667 Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression.
Patel AA et al. J Exp Med 2017; 214 (7):1913-1923 The fate and lifespan of human monocyte subsets in steady state and systemic inflammation.
Ott PA et al. Nature 2017; 547 (7662):217-221 An immunogenic personal neoantigen vaccine for patients with melanoma.
Zumwalde NA et al. JCI Insight 2017; 2 (13) Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model.
Fasbender F et al. Front Immunol 2017; 8:789 Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes.
Mou W et al. BMC Immunol 2017; 18 (1):36 γδTFH cells promote B cell maturation and antibody production in neuroblastoma.
Cant R et al. Front Immunol 2017; 8:809 Naltrexone Inhibits IL-6 and TNFα Production in Human Immune Cell Subsets following Stimulation with Ligands for Intracellular Toll-Like Receptors.
Wing JB et al. Proc Natl Acad Sci U S A 2017; 114 (31):E6400-E6409 A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers.
Cabrera CP et al. PLoS Med 2017; 14 (7):e1002352 Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study.
Johnson LE et al. J Immunother Cancer 2017; 5 (1):56 Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination.
Hazeldine J et al. PLoS Med 2017; 14 (7):e1002338 Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study.
Just SA et al. Respir Res 2017; 18 (1):141 Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis.
Magri G et al. Immunity 2017; 47 (1):118-134.e8 Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals.
Dai HS et al. Immunity 2017; 47 (1):159-170.e10 The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.
Lirussi D et al. EBioMedicine 2017; 22:100-111 Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway.
Guo Q et al. Sci Rep 2017; 7 (1):6627 Deformability based Cell Sorting using Microfluidic Ratchets Enabling Phenotypic Separation of Leukocytes Directly from Whole Blood.
Martinez-Varea A et al. J Perinat Med 2017; 45 (5):523-538 Clinical chorioamnionitis at term VII: the amniotic fluid cellular immune response.
Lunemann S et al. Sci Rep 2017; 7 (1):6676 Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells.
Costa VV et al. mBio 2017; 8 (4) Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules.
Winkler MS et al. PLoS One 2017; 12 (8):e0182427 Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression?
Burel JG et al. JCI Insight 2017; 2 (15) Dichotomous miR expression and immune responses following primary blood-stage malaria.
Ogunjimi B et al. J Clin Invest 2017; 127 (9):3543-3556 Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections.
Chitadze G et al. Oncoimmunology 2017; 6 (11):e1358839 In-depth immunophenotyping of patients with glioblastoma multiforme: Impact of steroid treatment.
Martrus G et al. PLoS One 2017; 12 (8):e0182532 Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells.
Rusconi M et al. Sci Rep 2017; 7 (1):7853 Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood.
Metzler G et al. J Immunol 2017; 199 (7):2249-2260 The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Yang M et al. Exp Ther Med 2017; 14 (4):3887-3893 CD19+CD24hiCD38hi regulatory B cells are associated with insulin resistance in type I Hashimoto's thyroiditis in Chinese females.
Booth JS et al. Cell Mol Gastroenterol Hepatol 2017; 4 (3):419-437 Systemic and Terminal Ileum Mucosal Immunity Elicited by Oral Immunization With the Ty21a Typhoid Vaccine in Humans.
Crespo J et al. Oncoimmunology 2017; 6 (12):e1362529 Phenotype and tissue distribution of CD28H+ immune cell subsets.
Leal Rojas IM et al. Front Immunol 2017; 8:971 Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells.
Gall VA et al. Cancer Res 2017; 77 (19):5374-5383 Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells.
Sanderson SL et al. Aging Cell 2017; 16 (6):1234-1243 In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Ubillos I et al. Front Immunol 2017; 8:966 Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells.
Foo SS et al. Nat Microbiol 2017; 2 (11):1558-1570 Asian Zika virus strains target CD14+ blood monocytes and induce M2-skewed immunosuppression during pregnancy.
Hashwah H et al. Proc Natl Acad Sci U S A 2017; 114 (36):9701-9706 Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
Wang WF et al. Nat Commun 2017; 8 (1):363 HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.
Berggren O et al. PLoS One 2017; 12 (8):e0183946 Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype.
Luk F et al. Front Immunol 2017; 8:1042 Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function.
Bruno TC et al. Cancer Immunol Res 2017; 5 (10):898-907 Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non-Small Cell Lung Cancer Patients.
Rechtien A et al. Cell Rep 2017; 20 (9):2251-2261 Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.
Sielatycka K et al. Stem Cell Rev Rep 2017; 13 (6):774-780 Novel View on Umbilical Cord Blood and Maternal Peripheral Blood-an Evidence for an Increase in the Number of Circulating Stem Cells on Both Sides of the Fetal-Maternal Circulation Barrier.
Nagasawa M et al. Front Immunol 2017; 8:1047 Human CD5+ Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34+ Progenitor Cells Is Regulated by Id2.
Ake JA et al. J Infect Dis 2017; 216 (9):1080-1090 Safety and Immunogenicity of PENNVAX-G DNA Prime Administered by Biojector 2000 or CELLECTRA Electroporation Device With Modified Vaccinia Ankara-CMDR Boost.
Mettananda S et al. Nat Commun 2017; 8 (1):424 Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Schwerd T et al. J Exp Med 2017; 214 (9):2547-2562 A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis.
Rai AK et al. Clin Exp Immunol 2017; 190 (3):340-350 Exonal switch down-regulates the expression of CD5 on blasts of acute T cell leukaemia.
Salio M et al. J Immunol 2017; 199 (8):2631-2638 Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.
Cardoso V et al. Nature 2017; 549 (7671):277-281 Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.
Klose CSN et al. Nature 2017; 549 (7671):282-286 The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.
Snir O et al. JCI Insight 2017; 2 (17) Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
Meeuwsen JAL et al. J Am Heart Assoc 2017; 6 (9) High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease.
Kyoizumi S et al. J Immunol 2017; 199 (8):2777-2793 Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors.
Kaiser Y et al. Front Immunol 2017; 8:1130 Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in L?fgren's Syndrome and Non-L?fgren's Syndrome Sarcoidosis.
Jagannathan P et al. Sci Rep 2017; 7 (1):11487 Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.
ManfrereC KCG et al. Oncotarget 2017; 8 (54):92183-92194 Profile of differentially expressed Toll-like receptor signaling genes in the natural killer cells of patients with S?zary syndrome.
Marcq E et al. Oncotarget 2017; 8 (52):89722-89735 Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients.
Reinisch A et al. Nat Protoc 2017; 12 (10):2169-2188 Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.
Bak RO et al. Elife 2017; 6 Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.
Choi YJ et al. Exp Mol Med 2017; 49 (9):e382 Impaired polyfunctionality of CD8+ T cells in severe sepsis patients with human cytomegalovirus reactivation.
Weiner J et al. Transplantation 2017; 101 (10):2449-2454 Long-term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation.
M?rklin M et al. Nat Commun 2017; 8 (1):755 NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Arthur Huang KY et al. Nat Commun 2017; 8 (1):762 Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children.
Ucar D et al. J Exp Med 2017; 214 (10):3123-3144 The chromatin accessibility signature of human immune aging stems from CD8+ T cells.
Abana CO et al. J Immunol 2017; 199 (9):3187-3201 Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.
Catalan-Dibene J et al. J Immunol 2017; 199 (9):3326-3335 Identification of IL-40, a Novel B Cell-Associated Cytokine.
Li J et al. J Immunol 2017; 199 (10):3504-3515 Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis.
Tothova Z et al. Cell Stem Cell 2017; 21 (4):547-555.e8 Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.
Jeong JH et al. Front Immunol 2017; 8:1260 CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis.
Espinosa V et al. Sci Immunol 2017; 2 (16) Type III interferon is a critical regulator of innate antifungal immunity.
Karampetsou MP et al. PLoS One 2017; 12 (10):e0186073 Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus.
Garz AK et al. Oncotarget 2017; 8 (65):108738-108759 Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations.
Boyle MJ et al. Front Immunol 2017; 8:1329 The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission.
Dahlin JS et al. Blood 2017; 130 (16):1785-1794 KIT signaling is dispensable for human mast cell progenitor development.
McFarlin BK et al. Front Physiol 2017; 8:786 Oral Supplementation with Baker's Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise.
Alroqi FJ et al. J Clin Immunol 2017; 37 (8):811-819 DOCK8 Deficiency Presenting as an IPEX-Like Disorder.
Smith AR et al. Blood Adv 2017; 1 (23):2083-2087 Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.
Herndler-Brandstetter D et al. Proc Natl Acad Sci U S A 2017; 114 (45):E9626-E9634 Humanized mouse model supports development, function, and tissue residency of human natural killer cells.
Keustermans G et al. PLoS One 2017; 12 (10):e0187068 Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.
Duyen HTL et al. Sci Rep 2017; 7 (1):14224 Skin dendritic cell and T cell activation associated with dengue shock syndrome.
Speir M et al. Sci Rep 2017; 7 (1):14273 Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins.
Fumey W et al. Sci Rep 2017; 7 (1):14289 Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo.
Zhou Y et al. Front Cell Infect Microbiol 2017; 7:457 Application of ImmunoScore Model for the Differentiation between Active Tuberculosis and Latent Tuberculosis Infection as Well as Monitoring Anti-tuberculosis Therapy.
Rivera-Correa J et al. Nat Commun 2017; 8 (1):1282 Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria.
He Y et al. Front Immunol 2017; 8:1435 Interferon-α-Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection.
Arkatkar T et al. J Exp Med 2017; 214 (11):3207-3217 B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
Duchartre Y et al. PLoS One 2017; 12 (11):e0187684 Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies.
Pinder CL et al. J Immunol 2017; 199 (12):4180-4188 Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry-Based Ig Capture Assay.
Gladkikh AA et al. Cancer Med 2017; 6 (12):2984-2997 Comparison of the mRNA expression profile of B-cell receptor components in normal CD5-high B-lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70.
Qin J et al. Biomed Res Int 2017; 2017:8431838 Increased Circulating Th17 but Decreased CD4+Foxp3+ Treg and CD19+CD1dhiCD5+ Breg Subsets in New-Onset Graves' Disease.
Marras F et al. J Virol 2017; 91 (23) Control of the HIV-1 DNA Reservoir Is Associated In Vivo and In Vitro with NKp46/NKp30 (CD335 CD337) Inducibility and Interferon Gamma Production by Transcriptionally Unique NK Cells.
Snijder B et al. Lancet Haematol 2017; 4 (12):e595-e606 Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study.
Basnett J et al. PLoS One 2017; 12 (11):e0188042 Regulation of the bone marrow microenvironment by G-CSF: Effects of G-CSF on acute lymphoblastic leukaemia.
Taurozzi AJ et al. PLoS One 2017; 12 (11):e0188228 Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program.
Eggers EL et al. JCI Insight 2017; 2 (22) Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.
Hu D et al. Nat Commun 2017; 8 (1):1600 Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis.
Santos RLA et al. Nat Commun 2017; 8 (1):1692 Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
Euteneuer F et al. Front Psychiatry 2017; 8:250 Peripheral Immune Alterations in Major Depression: The Role of Subtypes and Pathogenetic Characteristics.
Gomez-Tourino I et al. Nat Commun 2017; 8 (1):1792 T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
Paivandy A et al. Front Immunol 2017; 8:1645 Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells.
Strasser L et al. Sci Rep 2017; 7 (1):16638 Unbiased Quantitative Proteomics Reveals a Crucial Role of the Allergen Context for the Activation of Human Dendritic Cells.
Grifoni A et al. J Virol 2017; 91 (24) Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans.
Walker JA et al. Stem Cells Dev 2017; 26 (23):1715-1723 Humoral Immunity in Mice Transplanted with Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood Recapitulates That of Human Infants.
Alc?ntara-Hern?ndez M et al. Immunity 2017; 47 (6):1037-1050.e6 High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.
Lee HJ et al. Oncotarget 2017; 8 (69):113345-113359 Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer.
Urbansky A et al. Sci Rep 2017; 7 (1):17161 Rapid and effective enrichment of mononuclear cells from blood using acoustophoresis.
Pedros C et al. JCI Insight 2017; 2 (23) Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity.
Turaj AH et al. Cancer Cell 2017; 32 (6):777-791.e6 Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Sathe P et al. Int J Mol Sci 2017; 18 (12) Identification of Novel Human NK Cell Progenitor Subsets.
Soslow JH et al. Front Pharmacol 2017; 8:914 Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores.
Cosma G et al. Front Immunol 2017; 8:1771 Identifying the Presence of Prostate Cancer in Individuals with PSA Levels <20?ng ml-1 Using Computational Data Extraction Analysis of High Dimensional Peripheral Blood Flow Cytometric Phenotyping Data.
Canter RJ et al. J Immunother Cancer 2017; 5 (1):98 Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial.
Sander J et al. Immunity 2017; 47 (6):1051-1066.e12 Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Gavegnano C et al. PLoS Pathog 2017; 13 (12):e1006740 Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Panagoulias I et al. Front Immunol 2017; 8:1924 Ets-2 Acts As a Transcriptional Repressor of the Human Immunodeficiency Virus Type 1 through Binding to a Repressor-Activator Target Sequence of 5'-LTR.
Weinberg A et al. Front Immunol 2017; 8:2002 B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine.
B?zie S et al. Front Immunol 2017; 8:2014 Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/- Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice.
Anderson AE et al. Ann Rheum Dis 2016; 75 (2):466-73 IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.
Yong KS et al. Cell Mol Immunol 2016; 13 (5):605-14 Human CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.
Duggal NA et al. Biogerontology 2016; 17 (1):229-39 Development of depressive symptoms post hip fracture is associated with altered immunosuppressive phenotype in regulatory T and B lymphocytes.
Saulep-Easton D et al. Leukemia 2016; 30 (1):163-72 The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.
Huang X et al. Leukemia 2016; 30 (1):144-53 Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression.
Wright PB et al. Rheumatology (Oxford) 2016; 55 (1):120-32 Ankylosing spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation.
Lim TS et al. Oncoimmunology 2016; 5 (3):e1085146 PD-1 expression on dendritic cells suppresses CD8+ T cell function and antitumor immunity.
Bernardo D et al. Cell Mol Gastroenterol Hepatol 2016; 2 (1):22-39.e5 Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell?Recruitment to the Human Colon but Is Not Responsible?for?Differences Observed in Dendritic Cell?Subsets,?Phenotype, and Function Between the Proximal?and?Distal Colon.
Jindra PT et al. Biol Blood Marrow Transplant 2016; 22 (1):27-36 Analysis of a Genetic Polymorphism in the Costimulatory?Molecule TNFSF4 with Hematopoietic Stem?Cell?Transplant Outcomes.
Campi-Azevedo AC et al. Hum Vaccin Immunother 2016; 12 (2):491-502 Booster dose after 10 years is recommended following 17DD-YF primary vaccination.
Cook AM et al. Oncoimmunology 2016; 5 (3):e1066062 Dexamethasone co-medication in cancer patients undergoing chemotherapy causes substantial immunomodulatory effects with implications for chemo-immunotherapy strategies.
Yee CS et al. J Allergy Clin Immunol 2016; 137 (3):879-88.e2 Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association.
Marycz K et al. Stem Cells Int 2016; 2016:5756901 Endurance Exercise Mobilizes Developmentally Early Stem Cells into Peripheral Blood and Increases Their Number in Bone Marrow: Implications for Tissue Regeneration.
Venkatasubramanian S et al. Eur J Immunol 2016; 46 (2):464-79 Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.
Verron?se E et al. Oncoimmunology 2016; 5 (3):e1100791 Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay.
Gavin KM et al. FASEB J 2016; 30 (3):1096-108 De novo generation of adipocytes from circulating progenitor cells in mouse and human adipose tissue.
Slingluff CL Jr et al. Cancer Immunol Immunother 2016; 65 (1):25-36 A randomized pilot trial testing the safety and immunologic effects of a MAGE-A3 protein plus AS15 immunostimulant administered into muscle or into dermal/subcutaneous sites.
Tosh KW et al. J Immunol 2016; 196 (1):345-56 The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.
Kobayashi S et al. Eur J Immunol 2016; 46 (2):360-71 TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells.
Jabara HH et al. Nat Genet 2016; 48 (1):74-8 A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Chamberlain N et al. J Clin Invest 2016; 126 (1):282-7 Rituximab does not reset defective early B cell tolerance checkpoints.
Adamiak M et al. Leukemia 2016; 30 (4):919-28 Evidence that a lipolytic enzyme--hematopoietic-specific phospholipase C-β2--promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes.
Thome JJ et al. Nat Med 2016; 22 (1):72-7 Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues.
Nalivaiko K et al. Mol Ther 2016; 24 (2):298-305 A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells.
Henault J et al. Nat Immunol 2016; 17 (2):196-203 Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
Guo A et al. Oncotarget 2016; 7 (4):4598-610 Heightened BTK-dependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib.
Williams LR et al. J Virol 2016; 90 (2):947-58 Induction of the Lytic Cycle Sensitizes Epstein-Barr Virus-Infected B Cells to NK Cell Killing That Is Counteracted by Virus-Mediated NK Cell Evasion Mechanisms in the Late Lytic Cycle.
Deng C et al. Diabetes Care 2016; 39 (3):434-40 Altered Peripheral B-Lymphocyte Subsets in Type 1 Diabetes and Latent Autoimmune Diabetes in Adults.
Kyoizumi S et al. Radiat Res 2016; 185 (1):69-76 Circulating Hematopoietic Stem and Progenitor Cells in Aging Atomic Bomb Survivors.
De Grove KC et al. PLoS One 2016; 11 (1):e0145961 Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung.
Lewis MJ et al. Arthritis Res Ther 2016; 18:5 Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.
Joly-Battaglini A et al. F1000Res 2016; 5:38 Rituximab efficiently depletes B cells in lung tumors?and normal lung tissue.
Greco SH et al. J Leukoc Biol 2016; 100 (1):185-94 Mincle suppresses Toll-like receptor 4 activation.
Lang J et al. J Exp Med 2016; 213 (1):93-108 Receptor editing and genetic variability in human autoreactive B cells.
Nielsen CH et al. PLoS One 2016; 11 (1):e0146971 Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis.
Baglio SR et al. Proc Natl Acad Sci U S A 2016; 113 (5):E587-96 Sensing of latent EBV infection through exosomal transfer of 5'pppRNA.
Macal M et al. J Immunol 2016; 196 (4):1900-9 CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells.
Pearson C et al. Elife 2016; 5:e10066 ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
Frei AP et al. Nat Methods 2016; 13 (3):269-75 Highly multiplexed simultaneous detection of RNAs and proteins in single cells.
Guo XZ et al. Mol Ther Methods Clin Dev 2016; 3:15054 Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis.
Lin YC et al. Neurol Neuroimmunol Neuroinflamm 2016; 3 (1):e196 Patients with MS under daclizumab therapy mount normal immune responses to influenza vaccination.
Dahlin JS et al. Blood 2016; 127 (4):383-91 Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.
Roan F et al. J Immunol 2016; 196 (5):2051-2062 CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.
Llibre A et al. J Immunol 2016; 196 (5):2085-94 LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation.
Parente-Ribes A et al. Haematologica 2016; 101 (2):e59-62 Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells.
Geherin SA et al. J Immunol 2016; 196 (6):2514-2525 IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed Skin.
Ludigs K et al. Nat Commun 2016; 7:10554 NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions.
Le Nours J et al. Nat Commun 2016; 7:10570 Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Fresnay S et al. J Transl Med 2016; 14:62 Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans.
Sullivan RT et al. Malar J 2016; 15:139 B cell sub-types following acute malaria and associations with clinical immunity.
Edvardsen K et al. J Transl Med 2016; 14:68 Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease.
Wei?m?ller S et al. PLoS One 2016; 11 (3):e0149093 TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model.
Mattoo H et al. J Allergy Clin Immunol 2016; 138 (3):825-838 Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
Norstr?m MM et al. Oncotarget 2016; 7 (17):23581-93 Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes.
Serr I et al. Nat Commun 2016; 7:10991 Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
Liou LB et al. PLoS One 2016; 11 (3):e0151669 Sialyltransferase and Neuraminidase Levels/Ratios and Sialic Acid Levels in Peripheral Blood B Cells Correlate with Measures of Disease Activity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Pilot Study.
Hromadnikova I et al. PLoS One 2016; 11 (3):e0151535 Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B Cells and NKT Cells.
Coraglia A et al. J Immunol Res 2016; 2016:4951587 Common Variable Immunodeficiency and Circulating TFH.
Lee-Chang C et al. J Immunol 2016; 196 (8):3385-97 Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers.
Meffre E et al. JCI Insight 2016; 1 (3) Maturational characteristics of HIV-specific antibodies in viremic individuals.
Barsotti NS et al. PLoS One 2016; 11 (3):e0151761 IL-10-Producing Regulatory B Cells Are Decreased in Patients with Common Variable Immunodeficiency.
Leone DA et al. PLoS One 2016; 11 (3):e0151674 The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury.
Monticelli LA et al. Nat Immunol 2016; 17 (6):656-65 Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Jourdan M et al. Oncotarget 2016; 7 (19):28096-111 Differential effects of lenalidomide during plasma cell differentiation.
Tebbe B et al. PLoS One 2016; 11 (4):e0153170 Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes.
du Plessis WJ et al. PLoS One 2016; 11 (4):e0152710 The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis.
Fletcher HA et al. Nat Commun 2016; 7:11290 T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Garcia J et al. Sci Rep 2016; 6:24295 Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus.
Belov L et al. J Extracell Vesicles 2016; 5:25355 Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples.
Park JK et al. Arthritis Res Ther 2016; 18:91 HM71224, a novel Bruton's tyrosine kinase inhibitor, suppresses B cell and monocyte activation and ameliorates arthritis in a mouse model: a potential drug for rheumatoid arthritis.
Pugholm LH et al. J Immunol Res 2016; 2016:6391264 Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles.
Zhang C et al. Immunity 2016; 44 (4):913-923 CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.
Kajimura J et al. Mutat Res Genet Toxicol Environ Mutagen 2016; 802:59-65 Relationship between spontaneous γH2AX foci formation and progenitor functions in circulating hematopoietic stem and progenitor cells among atomic-bomb survivors.
Tossige-Gomes R et al. PLoS One 2016; 11 (4):e0153647 Lymphocyte Redox Imbalance and Reduced Proliferation after a Single Session of High Intensity Interval Exercise.
Rufener GA et al. Cancer Immunol Res 2016; 4 (6):509-19 Preserved Activity of CD20-Specific Chimeric Antigen Receptor-Expressing T Cells in the Presence of Rituximab.
Clement M et al. Front Immunol 2016; 7:158 Tertiary Lymphoid Organs in Takayasu Arteritis.
Loughland JR et al. Infect Immun 2016; 84 (5):1403-1412 Profoundly Reduced CD1c+ Myeloid Dendritic Cell HLA-DR and CD86 Expression and Increased Tumor Necrosis Factor Production in Experimental Human Blood-Stage Malaria Infection.
Lisenko K et al. Cancer Med 2016; 5 (7):1464-72 Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis.
Qualai J et al. PLoS One 2016; 11 (4):e0154253 Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential.
Rentas S et al. Nature 2016; 532 (7600):508-511 Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.
Jackson SW et al. J Exp Med 2016; 213 (5):733-50 B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
Lee SC et al. Nat Med 2016; 22 (6):672-8 Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
Pedros C et al. Nat Immunol 2016; 17 (7):825-33 A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.
Fromm PD et al. Oncoimmunology 2016; 5 (6):e1168555 CMRF-56(+) blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses.
Stikvoort A et al. PLoS One 2016; 11 (5):e0154737 Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant?
Perdomo-Celis F et al. Clin Vaccine Immunol 2016; 23 (5):417-426 Viability and Functionality of Cryopreserved Peripheral Blood Mononuclear Cells in Pediatric Dengue.
Gross CC et al. Proc Natl Acad Sci U S A 2016; 113 (21):E2973-82 Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.
Cheeseman HM et al. PLoS One 2016; 11 (5):e0154656 Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission.
Fletcher HA et al. BMC Med 2016; 14:76 Human newborn bacille Calmette-Gu?rin vaccination and risk of tuberculosis disease: a case-control study.
Dou DR et al. Nat Cell Biol 2016; 18 (6):595-606 Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Ma SD et al. PLoS Pathog 2016; 12 (5):e1005642 PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model.
G?bel K et al. Nat Commun 2016; 7:11626 Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Pennington LF et al. Nat Commun 2016; 7:11610 Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.
Forcade E et al. Blood 2016; 127 (20):2489-97 Circulating T follicular helper cells with increased function during chronic graft-versus-host disease.
Tullett KM et al. JCI Insight 2016; 1 (7):e87102 Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell recognition.
Albertini MR et al. Cancer Immunol Immunother 2016; 65 (8):897-907 Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma.
Park D et al. Histopathology 2016; 69 (3):516-21 Novel insights into the early histopathogenesis of immunodeficiency-associated Burkitt lymphoma: a case report of Burkitt microlymphoma arising within HIV lymphadenitis.
Reinisch A et al. Nat Med 2016; 22 (7):812-21 A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.
Schoenhals M et al. Cell Cycle 2016; 15 (14):1919-28 Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage.
Vaccari M et al. Nat Med 2016; 22 (7):762-70 Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Lima J et al. BMC Pregnancy Childbirth 2016; 16 (1):139 Characterization of B cells in healthy pregnant women from late pregnancy to post-partum: a prospective observational study.
Kim JH et al. Sci Rep 2016; 6:27615 Natural killer cells regulate eosinophilic inflammation in chronic rhinosinusitis.
Lee KS et al. PLoS One 2016; 11 (6):e0156979 Local Immune Responses in Children and Adults with Allergic and Nonallergic Rhinitis.
Urbansky A et al. Micromachines (Basel) 2016; 7 (6) Affinity-Bead-Mediated Enrichment of CD8+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Acoustophoresis.
Magnani CF et al. Oncotarget 2016; 7 (32):51581-51597 Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform.
Joosten SA et al. PLoS Pathog 2016; 12 (6):e1005687 Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.
Schr?der M et al. PLoS One 2016; 11 (6):e0157387 CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits.
Menard LC et al. JCI Insight 2016; 1 (9):e87310 B cells from African American lupus patients exhibit an activated phenotype.
O'Connor KS et al. Genes Immun 2016; 17 (6):328-34 IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection.
Tschan-Plessl A et al. Transplant Direct 2016; 2 (7):e89 Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro.
Li S et al. Nat Med 2016; 22 (7):792-9 Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Dan JM et al. J Immunol 2016; 197 (3):983-93 A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.
Wittmann A et al. J Biol Chem 2016; 291 (34):17629-38 Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells.
Rundberg Nilsson A et al. PLoS One 2016; 11 (7):e0158369 Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.
Zhang W et al. Oncotarget 2016; 7 (37):59098-59114 Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases.
Nagafuchi Y et al. Sci Rep 2016; 6:29338 Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4(+) T cells, and disease activity.
Koreth J et al. Blood 2016; 128 (1):130-7 Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease.
Saito A et al. J Virol 2016; 90 (15):6918-6935 Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.
Lindestam Arlehamn CS et al. PLoS Pathog 2016; 12 (7):e1005760 A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.
Akiyama M et al. Arthritis Res Ther 2016; 18:167 Enhanced IgG4 production by follicular helper 2?T cells and the involvement of follicular helper 1?T cells in the pathogenesis of IgG4-related disease.
Paroni M et al. Clin Transl Gastroenterol 2016; 7 (7):e182 Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy.
Jonas BA et al. PLoS One 2016; 11 (7):e0159189 Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
Schickel JN et al. Sci Immunol 2016; 1 (1) PTPN22 inhibition resets defective human central B cell tolerance.
Neumann L et al. J Immunol 2016; 197 (5):1801-8 Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients.
Muir R et al. PLoS Pathog 2016; 12 (7):e1005777 Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
Jacoby E et al. Nat Commun 2016; 7:12320 CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
du Plessis WJ et al. J Inflamm (Lond) 2016; 13:23 Phenotypic analysis of peripheral B cell populations during Mycobacterium tuberculosis infection and disease.
Sullivan KD et al. Elife 2016; 5 Trisomy 21 consistently activates the interferon response.
Jasek M et al. Tumour Biol 2016; 37 (10):13617-13626 Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia.
Comte D et al. Proc Natl Acad Sci U S A 2016; 113 (33):9321-6 Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus.
Cheng WC et al. Eur J Immunol 2016; 46 (9):2211-21 Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.
Demers KR et al. PLoS Pathog 2016; 12 (8):e1005805 Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
Cartellieri M et al. Blood Cancer J 2016; 6 (8):e458 Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts.
Zhong H et al. Hepat Mon 2016; 16 (9):e36068 Interleukin-7 in Patients With Chronic Hepatitis B May Have Effect on T Follicular Helper Cells and Specific Cellular Immunity.
van der Aa E et al. PLoS One 2016; 11 (8):e0161235 The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.
Ten Hacken E et al. J Immunol 2016; 197 (6):2522-31 Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.
Lizotte PH et al. Sci Rep 2016; 6:31745 Fine needle aspirate flow cytometric phenotyping characterizes immunosuppressive nature of the mesothelioma microenvironment.
Loh L et al. Proc Natl Acad Sci U S A 2016; 113 (36):10133-8 Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation.
Henry EK et al. J Exp Med 2016; 213 (9):1663-73 Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
Huynh L et al. Sci Rep 2016; 6:31959 Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages.
Toro JF et al. PLoS One 2016; 11 (8):e0161795 Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections.
Beschel LM et al. Oncotarget 2016; 7 (40):65902-65915 T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer.
Kurupati R et al. Oncotarget 2016; 7 (39):62898-62911 Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood.
Kleinsteuber K et al. Cytometry A 2016; 89 (10):903-913 Standardization and quality control for high-dimensional mass cytometry studies of human samples.
Chaves YO et al. Malar J 2016; 15 (1):445 Immune response pattern in recurrent Plasmodium vivax malaria.
Tomita Y et al. Oncoimmunology 2016; 5 (11):e1219008 The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat.
Fontana MF et al. PLoS One 2016; 11 (9):e0162132 A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection.
Sch?tz C et al. Oncotarget 2016; 7 (42):68503-68512 Antigen-specific T cell Redirectors: a nanoparticle based approach for redirecting T cells.
Malkiel S et al. Arthritis Rheumatol 2016; 68 (9):2210-20 Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry.
Cooke RE et al. J Transl Med 2016; 14:259 Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma.
Lu XJ et al. Nat Commun 2016; 7:12719 LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.
Price AA et al. Proc Natl Acad Sci U S A 2016; 113 (38):10678-83 Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype.
Lizotte PH et al. JCI Insight 2016; 1 (14):e89014 Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes.
Lai J et al. Blood 2016; 128 (10):1396-407 Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities.
Prabhu SB et al. PLoS One 2016; 11 (9):e0162242 Comparison of Human Neonatal and Adult Blood Leukocyte Subset Composition Phenotypes.
Williams GS et al. Oncotarget 2016; 7 (42):68278-68291 Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.
Wahid R et al. Clin Immunol 2016; 173:87-95 Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a.
Kalams SA et al. Eur J Contracept Reprod Health Care 2016; 21 (6):436-442 Neither vaginal nor buccal administration of 800?μg misoprostol alters mucosal and systemic immune activation or the cervicovaginal microbiome: a pilot study.
Guo H et al. J Exp Med 2016; 213 (10):2187-207 Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.
Andrews FH et al. Cell Rep 2016; 16 (12):3195-3207 Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Colluru VT et al. Oncotarget 2016; 7 (42):67901-67918 B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines.
Lake JE et al. HIV Clin Trials 2016; 17 (6):225-232 Telmisartan increases vascular reparative capacity in older HIV-infected adults: a pilot study.
Reinius B et al. Nat Genet 2016; 48 (11):1430-1435 Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.
Townsend CL et al. Front Immunol 2016; 7:388 Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions.
Su LF et al. Proc Natl Acad Sci U S A 2016; 113 (41):E6192-E6198 Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood.
Ho TC et al. Blood 2016; 128 (13):1671-8 Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.
Kinslow JD et al. Arthritis Rheumatol 2016; 68 (10):2372-83 Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Garcia J et al. Stem Cells Int 2016; 2016:6969726 Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat.
Albanese M et al. Proc Natl Acad Sci U S A 2016; 113 (42):E6467-E6475 Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
Cantaert T et al. J Clin Invest 2016; 126 (11):4289-4302 Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
Serr I et al. Proc Natl Acad Sci U S A 2016; 113 (43):E6659-E6668 miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
Su KY et al. J Immunol 2016; 197 (10):4163-4176 Efficient Culture of Human Naive and Memory B Cells for Use as APCs.
Chong SZ et al. J Exp Med 2016; 213 (11):2293-2314 CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
Massaad MJ et al. J Clin Invest 2016; 126 (11):4219-4236 Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
Ferreira-Teixeira M et al. BMC Med 2016; 14 (1):163 Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells.
Cuff AO et al. J Immunol 2016; 197 (11):4283-4291 Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.
Yiwen Z et al. Oncotarget 2016; 7 (47):77732-77748 Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy.
Carroll VA et al. Proc Natl Acad Sci U S A 2016; 113 (46):13168-13173 Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice.
Mackroth MS et al. PLoS Pathog 2016; 12 (11):e1005909 Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function.
Dam EM et al. Clin Immunol 2016; 173:171-180 The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.
Dendrou CA et al. Sci Transl Med 2016; 8 (363):363ra149 Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Seibert E et al. BMC Cardiovasc Disord 2016; 16 (1):210 Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease.
Dever DP et al. Nature 2016; 539 (7629):384-389 CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells.
DiGiusto DL et al. Mol Ther Methods Clin Dev 2016; 3:16067 Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells.
Sairafi D et al. J Immunol Res 2016; 2016:5601204 Donor Cell Composition and Reactivity Predict Risk of Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.
Sherbenou DW et al. J Clin Invest 2016; 126 (12):4640-4653 Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.
Boisvert M et al. J Immunol 2016; 197 (12):4848-4858 Novel E2 Glycoprotein Tetramer Detects Hepatitis C Virus-Specific Memory B Cells.
Tarunina M et al. Stem Cells Dev 2016; 25 (22):1709-1720 A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion.
Yeung YA et al. Nat Commun 2016; 7:13376 Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Kim L et al. Sci Rep 2016; 6:37295 Systemic and mucosal immune responses following oral adenoviral delivery of influenza vaccine to the human intestine by radio controlled capsule.
Skauli N et al. Genes (Basel) 2016; 7 (12) Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype.
Tomi? A et al. PLoS Pathog 2016; 12 (12):e1006015 Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand.
Bar-Ephraim YE et al. PLoS One 2016; 11 (12):e0167555 A Reproducible Method for Isolation and In Vitro Culture of Functional Human Lymphoid Stromal Cells from Tonsils.
Joshua V et al. Arthritis Res Ther 2016; 18 (1):284 Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells.
Cerny D et al. J Allergy Clin Immunol 2016; 138 (6):1709-1712.e11 Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence.
Kelly A et al. J Interferon Cytokine Res 2016; 36 (12):671-680 Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.
Martin VG et al. Front Immunol 2016; 7:546 Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm?
Seay HR et al. JCI Insight 2016; 1 (20):e88242 Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.
Lubaki NM et al. PLoS Pathog 2016; 12 (12):e1006031 The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.
Tzeng SJ et al. J Vis Exp 2016; (118) The Isolation, Differentiation, and Quantification of Human Antibody-secreting B Cells from Blood: ELISpot as a Functional Readout of Humoral Immunity.
Bergerson RJ et al. Blood Adv 2016; 1 (3):208-218 Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response.
Kinstrie R et al. Blood Adv 2016; 1 (3):160-169 Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia.
Wu GC et al. Nat Commun 2016; 7:13838 Temporal stability and molecular persistence of the bone marrow plasma cell antibody repertoire.
Llibre A et al. F1000Res 2016; 5:2929 Expression of lectin-like transcript-1 in human tissues.
Balandr?n JC et al. Front Immunol 2016; 7:666 Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis.
Jiang Z et al. Front Immunol 2016; 7:690 Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma.
Raine T et al. Gut 2015; 64 (2):250-9 Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease.
Della-Torre E et al. Ann Rheum Dis 2015; 74 (12):2236-43 B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease.
Platzer B et al. Mucosal Immunol 2015; 8 (3):516-32 Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites.
Doores KJ et al. J Virol 2015; 89 (2):1105-18 Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope.
Hoff P et al. Cell Mol Immunol 2015; 12 (4):483-92 Effects of 60-day bed rest with and without exercise on cellular and humoral immunological parameters.
Williams DW et al. J Leukoc Biol 2015; 97 (2):401-12 JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals.
Tungatt K et al. J Immunol 2015; 194 (1):463-74 Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.
Nunes-Caba?o H et al. J Virol 2015; 89 (4):2201-8 Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes.
Damuzzo V et al. Cytometry B Clin Cytom 2015; 88 (2):77-91 Complexity and challenges in defining myeloid-derived suppressor cells.
Brestoff JR et al. Nature 2015; 519 (7542):242-6 Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
Van Eyck L Jr et al. J Allergy Clin Immunol 2015; 135 (1):283-7.e5 Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.
Katawa G et al. PLoS Negl Trop Dis 2015; 9 (1):e3414 Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
Schinnerling K et al. Infect Immun 2015; 83 (2):482-91 Role of dendritic cells in the pathogenesis of Whipple's disease.
Otomo T et al. J Cell Biol 2015; 208 (2):171-80 Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions.
Spencer DH et al. Leukemia 2015; 29 (6):1279-89 Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
Scheuplein VA et al. J Virol 2015; 89 (7):3859-69 High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Botta Gordon-Smith S et al. Arthritis Rheumatol 2015; 67 (2):545-54 Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis.
Velazquez VM et al. Hepatology 2015; 61 (3):843-56 Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.
Poposki JA et al. Clin Exp Allergy 2015; 45 (2):384-93 Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis.
Boyle MJ et al. J Infect Dis 2015; 212 (3):416-25 Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
Lewis MJ et al. Am J Hum Genet 2015; 96 (2):221-34 UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
Fischbach H et al. Nat Commun 2015; 6:6199 Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets.
Okamura T et al. Nat Commun 2015; 6:6329 TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses.
Hoek KL et al. PLoS One 2015; 10 (2):e0118528 A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination.
Simchoni N et al. J Immunol 2015; 194 (7):3035-44 TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.
Breton G et al. J Exp Med 2015; 212 (3):401-13 Circulating precursors of human CD1c+ and CD141+ dendritic cells.
Lee J et al. J Exp Med 2015; 212 (3):385-99 Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow.
Cuthbert RJ et al. PLoS One 2015; 10 (3):e0117855 Examining the feasibility of clinical grade CD271+ enrichment of mesenchymal stromal cells for bone regeneration.
Garcia-Carmona Y et al. Blood 2015; 125 (11):1749-58 Differential induction of plasma cells by isoforms of human TACI.
Ohnuma K et al. J Immunol 2015; 194 (8):3697-712 Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.
Schilbach K et al. Oncoimmunology 2015; 4 (7):e1014760 Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.
Misra R et al. Hum Immunol 2015; 76 (5):329-338 Preterm cord blood CD4? T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4? T cells in bronchopulmonary dysplasia.
Hong M et al. Nat Commun 2015; 6:6588 Trained immunity in newborn infants of HBV-infected mothers.
McCracken MN et al. J Clin Invest 2015; 125 (5):1815-26 Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.
Hatzi K et al. J Exp Med 2015; 212 (4):539-53 BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.
Lin YC et al. Ann Clin Transl Neurol 2015; 2 (5):445-55 Daclizumab reverses intrathecal immune cell abnormalities in multiple sclerosis.
Wojno ED et al. Mucosal Immunol 2015; 8 (6):1313-23 The prostaglandin D? receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung.
Weinberg A et al. PLoS One 2015; 10 (4):e0122431 Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine.
Aybar LT et al. Clin Exp Immunol 2015; 180 (2):178-88 Reduced CD5(+) CD24(hi) CD38(hi) and interleukin-10(+) regulatory B cells in active anti-neutrophil cytoplasmic autoantibody-associated vasculitis permit increased circulating autoantibodies.
Gey A et al. Clin Exp Immunol 2015; 180 (2):280-8 Granulocytic myeloid-derived suppressor cells inversely correlate with plasma arginine and overall survival in critically ill patients.
Wahid R et al. Mucosal Immunol 2015; 8 (6):1349-59 Immunization with Ty21a live oral typhoid vaccine elicits crossreactive multifunctional CD8+ T-cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A, and S. Paratyphi B in humans.
Chimen M et al. Nat Med 2015; 21 (5):467-475 Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.
Pertovaara M et al. Clin Exp Immunol 2015; 181 (1):29-38 STAT-5 is activated constitutively in T cells, B cells and monocytes from patients with primary Sj?gren's syndrome.
Berent-Maoz B et al. PLoS One 2015; 10 (5):e0125414 The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2).
Li XX et al. Infect Dis Poverty 2015; 4:20 Profiling B and T cell immune responses to co-infection of Mycobacterium tuberculosis and hookworm in humans.
Mirza RE et al. J Pathol 2015; 236 (4):433-44 Macrophage PPARγ and impaired wound healing in type 2 diabetes.
Schinke C et al. Blood 2015; 125 (20):3144-52 IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.
Crompot E et al. PLoS One 2015; 10 (5):e0127209 Avoiding false positive antigen detection by flow cytometry on blood cell derived microparticles: the importance of an appropriate negative control.
Weiskopf D et al. J Infect Dis 2015; 212 (11):1743-51 Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets.
Elong Ngono A et al. J Immunol Res 2015; 2015:673503 Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis.
Zuber J et al. Am J Transplant 2015; 15 (10):2691-703 Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.
Sullivan RT et al. PLoS Pathog 2015; 11 (5):e1004894 FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure.
Samsonraj RM et al. Stem Cells 2015; 33 (6):1878-91 Establishing criteria for human mesenchymal stem cell potency.
McArthur MA et al. PLoS Pathog 2015; 11 (5):e1004914 Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
Yousef S et al. Hum Vaccin Immunother 2015; 11 (7):1606-11 CD229 is expressed on the surface of plasma cells carrying an aberrant phenotype and chemotherapy-resistant precursor cells in multiple myeloma.
Zhu D et al. Nat Med 2015; 21 (6):572-80 The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.
Yoshida Y et al. Arthritis Rheumatol 2015; 67 (6):1481-90 Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.
Salvatore G et al. J Lipid Res 2015; 56 (6):1110-22 Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
Boisson B et al. J Exp Med 2015; 212 (6):939-51 Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
Pusic I et al. Biol Blood Marrow Transplant 2015; 21 (10):1761-9 Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.
Koreth J et al. Biol Blood Marrow Transplant 2015; 21 (11):1907-13 A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial.
Rasmussen TK et al. Arthritis Res Ther 2015; 17:154 Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus.
Rancan C et al. PLoS Pathog 2015; 11 (6):e1004906 Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells.
Chiappini N et al. PLoS One 2015; 10 (6):e0129879 Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro.
Perriard G et al. J Neuroinflammation 2015; 12:119 Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Kuebler PJ et al. Proc Natl Acad Sci U S A 2015; 112 (27):8379-84 Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial.
Boer MC et al. Clin Vaccine Immunol 2015; 22 (7):778-88 Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults.
Vaeth M et al. J Immunol 2015; 195 (3):1202-17 Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.
Ruiter B et al. Clin Exp Allergy 2015; 45 (7):1214-25 Vitamins A and D have antagonistic effects on expression of effector cytokines and gut-homing integrin in human innate lymphoid cells.
Raval GU et al. Retrovirology 2015; 12:59 Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL.
Bekele Y et al. Medicine (Baltimore) 2015; 94 (27):e1125 Impaired Phenotype and Function of T Follicular Helper Cells in HIV-1-Infected Children Receiving ART.
Halliley JL et al. Immunity 2015; 43 (1):132-45 Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.
Fujii H et al. PLoS One 2015; 10 (7):e0133216 Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation.
Bodogai M et al. Cancer Res 2015; 75 (17):3456-65 Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.
Trinschek B et al. Int J Mol Sci 2015; 16 (7):16330-46 Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.
Jones N et al. Clin Exp Immunol 2015; 182 (1):69-80 Bioenergetic analysis of human peripheral blood mononuclear cells.
Mende N et al. J Exp Med 2015; 212 (8):1171-83 CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo.
Fischer U et al. Nat Genet 2015; 47 (9):1020-1029 Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Olesen R et al. J Virol 2015; 89 (20):10176-89 Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Chukwuma VU et al. PLoS One 2015; 10 (7):e0133509 Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.
Dolton G et al. Immunology 2015; 146 (1):11-22 More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers.
Teirlinck AC et al. Infect Immun 2015; 83 (9):3732-9 Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression.
Chen X et al. PLoS Negl Trop Dis 2015; 9 (8):e0004015 Distribution of Peripheral Memory T Follicular Helper Cells in Patients with Schistosomiasis Japonica.
Trend S et al. PLoS One 2015; 10 (8):e0135580 Leukocyte Populations in Human Preterm and Term Breast Milk Identified by Multicolour Flow Cytometry.
Muthumani K et al. Sci Transl Med 2015; 7 (301):301ra132 A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.
Quast I et al. Neurol Neuroimmunol Neuroinflamm 2015; 2 (5):e148 Deregulated Fcγ receptor expression in patients with CIDP.
Corkum CP et al. BMC Immunol 2015; 16:48 Immune cell subsets and their gene expression profiles from human PBMC isolated by Vacutainer Cell Preparation Tube (CPT?) and standard density gradient.
Roskin KM et al. Sci Transl Med 2015; 7 (302):302ra135 IgH sequences in common variable immune deficiency reveal altered B cell development and selection.
Mikosik A et al. PLoS One 2015; 10 (8):e0136615 Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.
Wostradowski T et al. Clin Exp Immunol 2015; 182 (2):162-72 Effect of interferon-β1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients.
Chambers ES et al. J Allergy Clin Immunol 2015; 136 (3):628-637.e4 Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol.
Catelas I et al. Clin Orthop Relat Res 2015; 473 (12):3903-14 Do patients with a failed metal-on-metal hip implant with a pseudotumor present differences in their peripheral blood lymphocyte subpopulations?
Matsui K et al. PLoS One 2015; 10 (9):e0137195 Circulating CXCR5?CD4? T Follicular-Like Helper Cell and Memory B Cell Responses to Human Papillomavirus Vaccines.
Gregorovic G et al. J Virol 2015; 89 (22):11711-4 Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice.
Alshevskaya AA et al. Mediators Inflamm 2015; 2015:948393 Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis.
Tian YF et al. Biomaterials 2015; 73:110-9 Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells.
Doisne JM et al. J Immunol 2015; 195 (8):3937-45 Composition, Development, and Function of Uterine Innate Lymphoid Cells.
Pala F et al. J Clin Invest 2015; 125 (10):3941-51 Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.
Booth JS et al. Front Immunol 2015; 6:466 Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection.
Kolhatkar NS et al. J Exp Med 2015; 212 (10):1663-77 Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.
Basha S et al. Clin Exp Immunol 2015; 182 (3):314-22 Poor memory B cell generation contributes to non-protective responses to DTaP vaccine antigens in otitis-prone children.
Uy GL et al. Leuk Res 2015; 39 (12):1437-42 Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia.
Ryotokuji K et al. Laser Ther 2015; 24 (3):179-88 Effect of Stress-Free Therapy on immune system: Induction of Interleukin 10 expression in lymphocytes through activation of CD19(+) CD24(hi) CD38(hi) regulatory B Cells.
Spel L et al. Oncotarget 2015; 6 (34):35770-81 Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma.
Tzeng SJ et al. J Biomed Sci 2015; 22:87 FcγRIIB mediates antigen-independent inhibition on human B lymphocytes through Btk and p38 MAPK.
Tsidulko AY et al. Oncotarget 2015; 6 (41):43529-39 Proteoglycan expression correlates with the phenotype of malignant and non-malignant EBV-positive B-cell lines.
Miles B et al. Nat Commun 2015; 6:8608 Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.
Lakhal-Naouar I et al. PLoS Negl Trop Dis 2015; 9 (10):e0004178 The Immunology of a Healing Response in Cutaneous Leishmaniasis Treated with Localized Heat or Systemic Antimonial Therapy.
Sohlberg E et al. Oncotarget 2015; 6 (33):34178-90 Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome.
Liu X et al. Onco Targets Ther 2015; 8:3095-104 Potential therapeutic strategy for gastric cancer peritoneal metastasis by NKG2D ligands-specific T cells.
Kim KW et al. Stem Cell Res Ther 2015; 6:202 Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease.
Colineau L et al. PLoS One 2015; 10 (10):e0140978 HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.
Duan Z et al. Oncotarget 2015; 6 (42):44239-53 Phenotype and function of CXCR5+CD45RA-CD4+ T cells were altered in HBV-related hepatocellular carcinoma and elevated serum CXCL13 predicted better prognosis.
Macauley MS et al. J Biol Chem 2015; 290 (50):30066-77 Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.
Dubois E et al. Neurol Neuroimmunol Neuroinflamm 2015; 2 (6):e177 Low frequencies of central memory CD4 T cells in progressive multifocal leukoencephalopathy.
Dutmer CM et al. J Clin Immunol 2015; 35 (8):754-60 Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection.
Moore JK et al. Cytotherapy 2015; 17 (11):1604-16 Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.
Qamar N et al. Clin Exp Allergy 2015; 45 (11):1663-72 Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells.
Arriaga-Pizano L et al. Arch Med Res 2015; 46 (8):651-8 Differential Immune Profiles in Two Pandemic Influenza A(H1N1)pdm09 Virus Waves at Pandemic Epicenter.
Gunther S et al. Front Immunol 2015; 6:556 Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.
Cubas R et al. J Immunol 2015; 195 (12):5625-36 Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Stockklausner C et al. Aging (Albany NY) 2015; 7 (11):911-27 A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition.
Wang J et al. Nat Biotechnol 2015; 33 (12):1256-1263 Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.
Omilusik KD et al. J Exp Med 2015; 212 (12):2027-39 Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection.
Dunmire SK et al. PLoS Pathog 2015; 11 (12):e1005286 The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events.
Andrews SF et al. Sci Transl Med 2015; 7 (316):316ra192 Immune history profoundly affects broadly protective B cell responses to influenza.
Yamagishi M et al. Sci Rep 2015; 5:17868 Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma.
Westman J et al. PLoS Pathog 2015; 11 (12):e1005319 Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.
Reyes-Avil?s E et al. PLoS One 2015; 10 (12):e0144629 Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy.
Yin J et al. Proc Natl Acad Sci U S A 2015; 112 (52):15988-93 Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity.
Drummond RA et al. PLoS Pathog 2015; 11 (12):e1005293 CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.
Bigler MB et al. PLoS One 2015; 10 (12):e0145635 Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels.
Lee SJ et al. BMC Cancer 2015; 15:1011 Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain.
Nowak WN et al. J Diabetes Investig 2014; 5 (1):99-107 Number of circulating pro-angiogenic cells, growth factor and anti-oxidative gene profiles might be altered in type 2 diabetes with and without diabetic foot syndrome.
Beliakova-Bethell N et al. Cytometry A 2014; 85 (1):94-104 The effect of cell subset isolation method on gene expression in leukocytes.
Lozza L et al. Eur J Immunol 2014; 44 (1):80-92 Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Gu?rin.
Krishnan S et al. J Infect Dis 2014; 209 (6):931-9 Evidence for innate immune system activation in HIV type 1-infected elite controllers.
Compeer EB et al. J Biol Chem 2014; 289 (1):520-8 Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation.
Trifonova RT et al. Am J Reprod Immunol 2014; 71 (3):252-64 Distribution of immune cells in the human cervix and implications for HIV transmission.
Chen Q et al. Proc Natl Acad Sci U S A 2014; 111 (4):1479-84 Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.
Beckwith KA et al. Leukemia 2014; 28 (7):1501-10 The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model.
Sereti I et al. PLoS Pathog 2014; 10 (1):e1003890 Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration.
Ramon S et al. Eur J Immunol 2014; 44 (2):357-69 Lipoxin A? modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism.
Schweingruber N et al. Acta Neuropathol 2014; 127 (5):713-29 Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses.
Mavropoulos A et al. J Immunol Res 2014; 2014:671431 Flow cytometric detection of p38 MAPK phosphorylation and intracellular cytokine expression in peripheral blood subpopulations from patients with autoimmune rheumatic diseases.
Huang J et al. PLoS One 2014; 9 (2):e88205 An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice.
Itoua Ma?ga R et al. Biomed Res Int 2014; 2014:536482 Flow cytometry assessment of in vitro generated CD138+ human plasma cells.
Mirza RE et al. Diabetes 2014; 63 (3):1103-14 Sustained inflammasome activity in macrophages impairs wound healing in type 2 diabetic humans and mice.
Yamahara K et al. PLoS One 2014; 9 (2):e88319 Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells.
H?nniger K et al. PLoS Comput Biol 2014; 10 (2):e1003479 A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood.
Chognard G et al. PLoS One 2014; 9 (2):e89092 The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.
Greer AM et al. J Clin Invest 2014; 124 (3):1187-98 Serum IgE clearance is facilitated by human FcεRI internalization.
Dutertre CA et al. PLoS One 2014; 9 (2):e89983 Deciphering the stromal and hematopoietic cell network of the adventitia from non-aneurysmal and aneurysmal human aorta.
Krummey SM et al. Am J Transplant 2014; 14 (3):607-14 High CTLA-4 expression on Th17 cells results in increased sensitivity to CTLA-4 coinhibition and resistance to belatacept.
Klco JM et al. Cancer Cell 2014; 25 (3):379-92 Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
Baravalle G et al. J Immunol 2014; 192 (7):3280-8 Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model.
Walkowski S et al. PLoS One 2014; 9 (3):e90132 Osteopathic manipulative therapy induces early plasma cytokine release and mobilization of a population of blood dendritic cells.
Glauzy S et al. PLoS One 2014; 9 (3):e91492 CXCR4-related increase of circulating human lymphoid progenitors after allogeneic hematopoietic stem cell transplantation.
Imam S et al. Endocr Relat Cancer 2014; 21 (3):505-16 Lymphocytic profiling in thyroid cancer provides clues for failure of tumor immunity.
Nguyen KD et al. Mol Immunol 2014; 59 (2):172-9 Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation.
Rongvaux A et al. Nat Biotechnol 2014; 32 (4):364-72 Development and function of human innate immune cells in a humanized mouse model.
Pa?no T et al. PLoS One 2014; 9 (3):e92378 Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines.
Sennikov SV et al. Mediators Inflamm 2014; 2014:745909 Polymorphisms in the tumor necrosis factor receptor genes affect the expression levels of membrane-bound type I and type II receptors.
Abramowski P et al. PLoS One 2014; 9 (3):e91970 The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response.
Mukthavaram R et al. J Control Release 2014; 183:146-53 Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes.
Cartellieri M et al. PLoS One 2014; 9 (4):e93745 A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells.
Todd SK et al. Rheumatology (Oxford) 2014; 53 (9):1693-703 Regulatory B cells are numerically but not functionally deficient in anti-neutrophil cytoplasm antibody-associated vasculitis.
Breton CS et al. J Hematol Oncol 2014; 7:33 A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies.
Dhodapkar MV et al. Sci Transl Med 2014; 6 (232):232ra51 Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.
Deng N et al. PLoS One 2014; 9 (5):e95986 Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells.
Wege AK et al. MAbs 2014; 6 (4):968-77 Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies.
Wilson EM et al. J Infect Dis 2014; 210 (9):1396-406 Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection.
Gutzeit C et al. J Immunol 2014; 192 (12):5852-62 Exosomes derived from Burkitt's lymphoma cell lines induce proliferation, differentiation, and class-switch recombination in B cells.
Werner-Klein M et al. PLoS One 2014; 9 (5):e97860 Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients.
Geffner L et al. PLoS One 2014; 9 (5):e97837 Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cells.
Kyoizumi S et al. J Immunol 2014; 192 (12):5749-60 Linkage between dendritic and T cell commitments in human circulating hematopoietic progenitors.
Rossi EA et al. PLoS One 2014; 9 (5):e98315 Anti-CD22/CD20 Bispecific antibody with enhanced trogocytosis for treatment of Lupus.
Graves AJ et al. Cytometry A 2014; 85 (7):576-9 OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Martin E et al. Nature 2014; 510 (7504):288-92 CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation.
Steinsb? ? et al. Nat Commun 2014; 5:4041 Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells.
Suszynska M et al. J Ovarian Res 2014; 7:66 Expression of the erythropoietin receptor by germline-derived cells - further support for a potential developmental link between the germline and hematopoiesis.
Conforti A et al. Stem Cells Dev 2014; 23 (21):2591-9 Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro.
Booth JS et al. Front Immunol 2014; 5:294 Characterization and functional properties of gastric tissue-resident memory T cells from children, adults, and the elderly.
Krupna-Gaylord MA et al. PLoS One 2014; 9 (6):e100174 Induction of type I and type III interferons by Borrelia burgdorferi correlates with pathogenesis and requires linear plasmid 36.
Masuda H et al. J Am Heart Assoc 2014; 3 (3):e000743 Vasculogenic conditioning of peripheral blood mononuclear cells promotes endothelial progenitor cell expansion and phenotype transition of anti-inflammatory macrophage and T lymphocyte to cells with regenerative potential.
Jo J et al. PLoS Pathog 2014; 10 (6):e1004210 Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.
Melchiotti R et al. BMC Med Genet 2014; 15:73 Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39.
Lepore M et al. J Exp Med 2014; 211 (7):1363-77 A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.
Sandler VM et al. Nature 2014; 511 (7509):312-8 Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Du Q et al. BMC Med Genomics 2014; 7:42 Placental gene-expression profiles of intrahepatic cholestasis of pregnancy reveal involvement of multiple molecular pathways in blood vessel formation and inflammation.
Kawasaki N et al. J Immunol 2014; 193 (4):1560-6 Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation.
Zhu D et al. Clin Exp Immunol 2014; 177 (2):464-77 Suppression of allo-human leucocyte antigen (HLA) antibodies secreted by B memory cells in vitro: intravenous immunoglobulin (IVIg)?versus a monoclonal anti-HLA-E IgG that mimics HLA-I reactivities of IVIg.
Herrera AF et al. Biol Blood Marrow Transplant 2014; 20 (11):1737-43 A phase II study of bortezomib plus prednisone for initial therapy of chronic graft-versus-host disease.
Lozza L et al. Front Immunol 2014; 5:324 Communication between Human Dendritic Cell Subsets in Tuberculosis: Requirements for Naive CD4(+) T Cell Stimulation.
Scholzen A et al. PLoS One 2014; 9 (7):e102885 Expansion of IgG+ B-cells during mitogen stimulation for memory B-cell ELISpot analysis is influenced by size and composition of the B-cell pool.
Picchianti Diamanti A et al. Clin Exp Immunol 2014; 177 (3):630-40 Abatacept (cytotoxic T lymphocyte antigen 4-immunoglobulin) improves B cell function and regulatory T cell inhibitory capacity in rheumatoid arthritis patients non-responding to anti-tumour necrosis factor-α agents.
Sag D et al. J Clin Invest 2014; 124 (9):3725-40 IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset.
Longman RS et al. J Exp Med 2014; 211 (8):1571-83 CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
Wang D et al. Arthritis Rheumatol 2014; 66 (8):2234-45 A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus.
Arlehamn CL et al. J Immunol 2014; 193 (6):2931-40 Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features.
Jergovi? M et al. Allergy Asthma Clin Immunol 2014; 10 (1):43 Patients with posttraumatic stress disorder exhibit an altered phenotype of regulatory T cells.
van Baarsen LG et al. Arthritis Res Ther 2014; 16 (4):426 Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?
Antsiferova O et al. PLoS Pathog 2014; 10 (8):e1004333 Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice.
Lee-Chang C et al. Blood 2014; 124 (9):1450-9 Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity.
Amu S et al. Retrovirology 2014; 11:76 Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART.
Yu CI et al. J Immunol 2014; 193 (9):4335-43 Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines.
Cucak H et al. PLoS One 2014; 9 (9):e107140 Reduction of specific circulating lymphocyte populations with metabolic risk factors in patients at risk to develop type 2 diabetes.
Hodgson SH et al. Mol Ther 2014; 22 (12):2142-2154 Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial.
Chen D et al. J Immunol 2014; 193 (10):4823-32 Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone marrow and spinal cord while preserving peripheral regulatory mechanisms.
Grozdanov V et al. Acta Neuropathol 2014; 128 (5):651-63 Inflammatory dysregulation of blood monocytes in Parkinson's disease patients.
Nagel A et al. PLoS One 2014; 9 (10):e110138 CD3-positive B cells: a storage-dependent phenomenon.
Yaktapour N et al. J Clin Invest 2014; 124 (11):5074-84 BRAF inhibitor-associated ERK activation drives development of chronic lymphocytic leukemia.
Kim TJ et al. Nat Commun 2014; 5:5317 Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients.
Heninger AK et al. Immun Inflamm Dis 2014; 2 (3):166-80 Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex?.
Neller MA et al. PLoS One 2014; 9 (11):e110741 High efficiency ex vivo cloning of antigen-specific human effector T cells.
Camacho-Sandoval R et al. Clin Exp Immunol 2014; 178 (3):489-503 Differential partial activation phenotype and production of tumour necrosis factor-α by conventional dendritic cells in response to lipopolysaccharide in HIV+ viraemic subjects and HIV+ controllers.
Jaafoura S et al. Nat Commun 2014; 5:5407 Progressive contraction of the latent HIV reservoir around a core of less-differentiated CD4? memory T Cells.
Vogel K et al. Immunology 2014; 143 (4):588-600 Both plasmacytoid dendritic cells and monocytes stimulate natural killer cells early during human herpes simplex virus type 1 infections.
R?lle A et al. J Clin Invest 2014; 124 (12):5305-16 IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion.
White CA et al. J Immunol 2014; 193 (12):5933-50 Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses.
Willmann KL et al. Nat Commun 2014; 5:5360 Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.
Braun M et al. PLoS Pathog 2014; 10 (11):e1004521 NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression.
Porichis F et al. Nat Commun 2014; 5:5641 High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry.
Meijerink H et al. BMC Infect Dis 2014; 14:683 The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study.
Hosgood HD 3rd et al. Am J Ind Med 2013; 56 (2):252-7 Occupational exposure to formaldehyde and alterations in lymphocyte subsets.
DiLillo DJ et al. Leukemia 2013; 27 (1):170-82 Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.
Eto H et al. Stem Cells Dev 2013; 22 (6):985-97 Characterization of human adipose tissue-resident hematopoietic cell populations reveals a novel macrophage subpopulation with CD34 expression and mesenchymal multipotency.
Garcia-Bates TM et al. J Immunol 2013; 190 (1):80-7 Association between magnitude of the virus-specific plasmablast response and disease severity in dengue patients.
McArthur MA et al. Clin Immunol 2013; 146 (2):140-52 Unexpected heterogeneity of multifunctional T cells in response to superantigen stimulation in humans.
Terahara K et al. PLoS One 2013; 8 (1):e53495 Expansion of activated memory CD4+ T cells affects infectivity of CCR5-tropic HIV-1 in humanized NOD/SCID/JAK3null mice.
Karapetyan AV et al. Stem Cells Dev 2013; 22 (11):1645-56 Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction.
Bunch DO et al. Clin J Am Soc Nephrol 2013; 8 (3):382-91 Decreased CD5? B cells in active ANCA vasculitis and relapse after rituximab.
Kapoor N et al. PLoS One 2013; 8 (1):e53657 Human granuloma in vitro model, for TB dormancy and resuscitation.
Lang J et al. J Immunol 2013; 190 (5):2090-101 Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation.
Xibing G et al. Hepat Mon 2013; 13 (1):e6221 Relationship between HBV genotypes B, C and follicular helper T cells in patients with chronic hepatitis B and its significance.
DeKosky BJ et al. Nat Biotechnol 2013; 31 (2):166-9 High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.
De Oliveira SN et al. J Transl Med 2013; 11:23 A CD19/Fc fusion protein for detection of anti-CD19 chimeric antigen receptors.
Cattaneo F et al. J Allergy Clin Immunol 2013; 131 (4):1136-45 Hypomorphic Janus kinase 3 mutations result in a spectrum of immune defects, including partial maternal T-cell engraftment.
Tavano B et al. J Immunol 2013; 190 (6):2622-30 Ig-like transcript 7, but not bone marrow stromal cell antigen 2 (also known as HM1.24, tetherin, or CD317), modulates plasmacytoid dendritic cell function in primary human blood leukocytes.
Amabile G et al. Blood 2013; 121 (8):1255-64 In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.
Fernandez-Arias C et al. J Immunol 2013; 190 (7):3363-72 Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.
Barnig C et al. Sci Transl Med 2013; 5 (174):174ra26 Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma.
Labuda LA et al. PLoS Negl Trop Dis 2013; 7 (3):e2094 Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis.
Melton AC et al. PLoS One 2013; 8 (3):e58966 Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation.
Cubas RA et al. Nat Med 2013; 19 (4):494-9 Inadequate T follicular cell help impairs B cell immunity during HIV infection.
Hedges JF et al. J Immunol 2013; 190 (8):4263-73 Solute carrier 11A1 is expressed by innate lymphocytes and augments their activation.
St Clair EW et al. Arthritis Rheum 2013; 65 (4):1097-106 Rituximab therapy for primary Sj?gren's syndrome: an open-label clinical trial and mechanistic analysis.
Ly D et al. J Exp Med 2013; 210 (4):729-41 CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.
Hostmann A et al. Immunology 2013; 139 (1):100-8 Dendritic cells from human mesenteric lymph nodes in inflammatory and non-inflammatory bowel diseases: subsets and function of plasmacytoid dendritic cells.
von Bonin M et al. PLoS One 2013; 8 (4):e60680 In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice.
Li L et al. Mol Ther 2013; 21 (6):1259-69 Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases.
Negash AA et al. PLoS Pathog 2013; 9 (4):e1003330 IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease.
Ernst W et al. Infect Immun 2013; 81 (5):1520-31 Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis.
Kirchberger S et al. J Exp Med 2013; 210 (5):917-31 Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model.
Segura E et al. J Exp Med 2013; 210 (5):1035-47 Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells.
Kyoizumi S et al. J Immunol 2013; 190 (12):6164-72 Age-associated changes in the differentiation potentials of human circulating hematopoietic progenitors to T- or NK-lineage cells.
Danso-Abeam D et al. Orphanet J Rare Dis 2013; 8:79 Olmsted syndrome: exploration of the immunological phenotype.
Jabara HH et al. J Allergy Clin Immunol 2013; 132 (1):151-8 A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.
Sangster MY et al. Clin Vaccine Immunol 2013; 20 (6):867-76 B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination.
Pelletier S et al. J Virol 2013; 87 (12):6769-81 Sustained hyperresponsiveness of dendritic cells is associated with spontaneous resolution of acute hepatitis C.
Mirza RE et al. Diabetes 2013; 62 (7):2579-87 Blocking interleukin-1β induces a healing-associated wound macrophage phenotype and improves healing in type 2 diabetes.
Pupovac A et al. Purinergic Signal 2013; 9 (4):609-19 CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation.
Lockridge JL et al. Biol Blood Marrow Transplant 2013; 19 (9):1310-22 Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease.
Krejsa CM et al. PLoS One 2013; 8 (6):e67256 Interleukin-21 enhances rituximab activity in a cynomolgus monkey model of B cell depletion and in mouse B cell lymphoma models.
Preston SG et al. PLoS Pathog 2013; 9 (6):e1003450 Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses.
Santer DM et al. PLoS One 2013; 8 (6):e68308 Enhanced activation of memory, but not na?ve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis.
Pinho S et al. J Exp Med 2013; 210 (7):1351-67 PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.
Dintwe OB et al. Eur J Immunol 2013; 43 (9):2409-20 Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function.
H?rl S et al. Leukemia 2013; 27 (11):2200-8 Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity.
Duggal NA et al. Aging Cell 2013; 12 (5):873-81 An age-related numerical and functional deficit in CD19(+) CD24(hi) CD38(hi) B cells is associated with an increase in systemic autoimmunity.
Noti M et al. Nat Med 2013; 19 (8):1005-13 Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.
Li W et al. Hum Gene Ther 2013; 24 (8):751-60 Cytosine arabinoside promotes cytotoxic effect of T cells on leukemia cells mediated by bispecific antibody.
Williams DW et al. PLoS One 2013; 8 (7):e69270 Mechanisms of HIV entry into the CNS: increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in diapedesis.
Jensen K et al. PLoS One 2013; 8 (7):e70721 Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations.
Derkow K et al. PLoS One 2013; 8 (8):e70626 Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-β includes upregulation of TLR7 in plasmacytoid dendritic cells.
Mensen A et al. J Transl Med 2013; 11:188 Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Ivarsson MA et al. J Clin Invest 2013; 123 (9):3889-901 Differentiation and functional regulation of human fetal NK cells.
Chang CJ et al. PLoS One 2013; 8 (8):e72037 Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility.
Chan MA et al. Clin Transl Allergy 2013; 3 (1):29 Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells.
Putnam AL et al. Am J Transplant 2013; 13 (11):3010-20 Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation.
Le Coz C et al. PLoS One 2013; 8 (9):e75319 Circulating TFH subset distribution is strongly affected in lupus patients with an active disease.
Hauber I et al. PLoS Pathog 2013; 9 (9):e1003587 Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice.
Jordan KR et al. Cancer Immunol Immunother 2013; 62 (11):1711-22 Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients.
Lee DH et al. J Neuroinflammation 2013; 10:123 Immunological and clinical consequences of splenectomy in a multiple sclerosis patient treated with natalizumab.
Tazawa H et al. Blood 2013; 122 (15):2582-90 Blockade of invariant TCR-CD1d interaction specifically inhibits antibody production against blood group A carbohydrates.
Trinschek B et al. PLoS One 2013; 8 (10):e77634 Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis.
Xu X et al. PLoS One 2013; 8 (10):e77401 Changes of cytokines during a spaceflight analog--a 45-day head-down bed rest.
de la Morena-Barrio ME et al. Orphanet J Rare Dis 2013; 8:170 GPI-anchor and GPI-anchored protein expression in PMM2-CDG patients.
Abbott RJ et al. J Immunol 2013; 191 (11):5398-409 CD8+ T cell responses to lytic EBV infection: late antigen specificities as subdominant components of the total response.
J?ger N et al. Cell 2013; 155 (3):567-81 Hypermutation of the inactive X chromosome is a frequent event in cancer.
Jelicic K et al. Nat Immunol 2013; 14 (12):1256-65 The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.
Brisslert M et al. Immunology 2013; 140 (4):421-9 Epstein-Barr virus infection transforms CD25+ B cells into antibody-secreting cells in rheumatoid arthritis patients.
McWilliams L et al. J Leukoc Biol 2013; 94 (5):991-1001 The human fetal lymphocyte lineage: identification by CD27 and LIN28B expression in B cell progenitors.
Sridharan A et al. J Virol 2013; 87 (21):11648-58 Inhibition of megakaryocyte development in the bone marrow underlies dengue virus-induced thrombocytopenia in humanized mice.
Roselli M et al. Oncoimmunology 2013; 2 (10):e27025 Effects of conventional therapeutic interventions on the number and function of regulatory T cells.
Pozzo F et al. J Hematol Oncol 2013; 6:83 Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application.
Aucher A et al. J Immunol 2013; 191 (12):6250-60 MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation.
Sok D et al. PLoS Pathog 2013; 9 (11):e1003754 The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.
Weidner CI et al. Sci Rep 2013; 3:3372 Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture.
Saghafian-Hedengren S et al. J Virol 2013; 87 (24):13446-55 Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells.
Siracusa MC et al. Immunity 2013; 39 (6):1158-70 Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.
Koo J et al. Immune Netw 2013; 13 (6):240-8 Increased Lymphocyte Infiltration in Rheumatoid Arthritis Is Correlated with an Increase in LTi-like Cells in Synovial Fluid.
Degauque N et al. PLoS One 2013; 8 (12):e84273 Characterization of antigen-specific B cells using nominal antigen-coated flow-beads.
Renand A et al. PLoS One 2013; 8 (12):e85589 Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs.
Jung HJ et al. Exp Hematol 2012; 40 (2):107-18.e2 Bortezomib-resistant nuclear factor κB expression in stem-like cells in mantle cell lymphoma.
Santer DM et al. J Immunol 2012; 188 (2):902-15 Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes.
Weigert O et al. Cancer Discov 2012; 2 (1):47-55 Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation.
Hippen KL et al. Blood 2012; 119 (2):619-28 Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.
Zou J et al. Ann Hematol 2012; 91 (6):813-23 Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells.
Waldron-Lynch F et al. Sci Transl Med 2012; 4 (118):118ra12 Teplizumab induces human gut-tropic regulatory cells in humanized mice and patients.
Raghuraman S et al. J Infect Dis 2012; 205 (5):763-71 Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion.
Smedman C et al. Scand J Immunol 2012; 75 (2):249-58 FluoroSpot Analysis of TLR-Activated Monocytes Reveals Several Distinct Cytokine-Secreting Subpopulations.
van der Vlugt LE et al. PLoS One 2012; 7 (2):e30883 Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.
Tyler C et al. Am J Reprod Immunol 2012; 68 (1):28-37 The mucin MUC16 (CA125) binds to NK cells and monocytes from peripheral blood of women with healthy pregnancy and preeclampsia.
Wingender G et al. J Immunol 2012; 188 (7):3000-8 Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans.
White RE et al. J Clin Invest 2012; 122 (4):1487-502 EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.
Jung HJ et al. Blood 2012; 119 (11):2568-78 Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities.
Kroenke MA et al. J Immunol 2012; 188 (8):3734-44 Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation.
Mahnke YD et al. Blood 2012; 119 (13):3105-12 Selective expansion of polyfunctional pathogen-specific CD4(+) T cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome.
Brindley SM et al. Hepatology 2012; 55 (4):1130-8 Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells.
Tarlton NJ et al. Inflamm Bowel Dis 2012; 18 (12):2381-91 Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis.
Diehl SA et al. Immunol Cell Biol 2012; 90 (8):802-11 IL-6 triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells.
Ten Berge B et al. Respir Res 2012; 13:33 Evidence for local dendritic cell activation in pulmonary sarcoidosis.
Mori F et al. Blood Cancer J 2012; 2 (4):e67 Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model.
DeBell KE et al. BMC Immunol 2012; 13:23 Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a.
Ippolito GC et al. PLoS One 2012; 7 (4):e35497 Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.
Walker JE et al. J Virol 2012; 86 (10):5719-29 Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.
Sada-Ovalle I et al. Clin Exp Immunol 2012; 168 (2):200-6 Functionality of CD4+ and CD8+ T cells from tonsillar tissue.
Jabara HH et al. Nat Immunol 2012; 13 (6):612-20 DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Rech AJ et al. Sci Transl Med 2012; 4 (134):134ra62 CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
Somanchi SS et al. Blood 2012; 119 (22):5164-72 Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7.
Simpfendorfer KR et al. Hum Mol Genet 2012; 21 (17):3918-25 The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development.
Qi Y et al. PLoS One 2012; 7 (6):e39072 The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
Chen K et al. PLoS One 2012; 7 (6):e39294 Human solid tumor xenografts in immunodeficient mice are vulnerable to lymphomagenesis associated with Epstein-Barr virus.
Pa?no T et al. Haematologica 2012; 97 (7):1110-4 CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype.
Gros F et al. Autophagy 2012; 8 (7):1113-23 Macroautophagy is deregulated in murine and human lupus T lymphocytes.
Kawano Y et al. Int J Oncol 2012; 41 (3):876-84 Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide.
Gartner S et al. PLoS One 2012; 7 (7):e40139 De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.
Daigneault M et al. PLoS Pathog 2012; 8 (7):e1002814 Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.
Wege AK et al. PLoS Negl Trop Dis 2012; 6 (7):e1741 Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.
Gros A et al. Clin Cancer Res 2012; 18 (19):5212-23 Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma.
Vicetti Miguel RD et al. J Immunol Methods 2012; 384 (1-2):191-5 Brefeldin A, but not monensin, enables flow cytometric detection of interleukin-4 within peripheral T cells responding to ex vivo stimulation with Chlamydia trachomatis.
Xuan L et al. J Hematol Oncol 2012; 5:46 Effects of intensified conditioning on Epstein-Barr virus and cytomegalovirus infections in allogeneic hematopoietic stem cell transplantation for hematological malignancies.
Koreth J et al. J Clin Oncol 2012; 30 (26):3202-8 Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation.
Barreyro L et al. Blood 2012; 120 (6):1290-8 Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.
Butler JM et al. Blood 2012; 120 (6):1344-7 Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells.
Bility MT et al. Nat Protoc 2012; 7 (9):1608-17 Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis.
Hubo M et al. PLoS One 2012; 7 (8):e44056 Plasmacytoid dendritic cells are inefficient in activation of human regulatory T cells.
Zhu YY et al. PLoS One 2012; 7 (8):e44131 The largely normal response to Toll-like receptor 7 and 9 stimulation and the enhanced expression of SIGIRR by B cells in systemic lupus erythematosus.
Barbosa RR et al. Clin Exp Immunol 2012; 169 (3):263-72 Monocyte activation is a feature of common variable immunodeficiency irrespective of plasma lipopolysaccharide levels.
Zeng X et al. Immunity 2012; 37 (3):524-34 γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.
Hwang I et al. Int Immunol 2012; 24 (12):793-802 Identification of human NK cells that are deficient for signaling adaptor FcRγ and specialized for antibody-dependent immune functions.
Jung HJ et al. Am J Hematol 2012; 87 (12):1057-64 Synergistic anticancer effects of arsenic trioxide with bortezomib in mantle cell lymphoma.
Alkanani AK et al. Diabetes 2012; 61 (10):2525-33 Dysregulated Toll-like receptor-induced interleukin-1β and interleukin-6 responses in subjects at risk for the development of type 1 diabetes.
Misharin AV et al. J Transl Med 2012; 10:190 Development of a new humanized mouse model to study acute inflammatory arthritis.
Hensley TR et al. J Vis Exp 2012; (67):e4302 Enumeration of major peripheral blood leukocyte populations for multicenter clinical trials using a whole blood phenotyping assay.
Kotowski M et al. BMC Pediatr 2012; 12:148 Circulating hematopoietic stem cell count is a valuable predictor of prematurity complications in preterm newborns.
Nakayama S et al. Diagn Pathol 2012; 7:131 An approach for diagnosing plasma cell myeloma by three-color flow cytometry based on kappa/lambda ratios of CD38-gated CD138(+) cells.
Weigand LU et al. Immunology 2012; 137 (3):226-38 Isolation of human MHC class II-restricted T cell receptors from the autologous T-cell repertoire with potent anti-leukaemic reactivity.
Scholbach J et al. PLoS One 2012; 7 (10):e46772 Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice.
Perona-Wright G et al. Proc Natl Acad Sci U S A 2012; 109 (45):18535-40 Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response.
Wang QJ et al. Cancer Res 2012; 72 (23):6119-29 Distinctive features of the differentiated phenotype and infiltration of tumor-reactive lymphocytes in clear cell renal cell carcinoma.
Chen Q et al. J Immunol 2012; 189 (11):5223-9 GM-CSF and IL-4 stimulate antibody responses in humanized mice by promoting T, B, and dendritic cell maturation.
Zha B et al. PLoS One 2012; 7 (11):e49835 Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease.
Stasio?ek M et al. Thyroid Res 2012; 5 (1):18 Distribution of subpopulations of dendritic cells in peripheral blood of patients treated with exogenous thyrotropin.
Velazquez VM et al. Hepatology 2012; 56 (6):2071-81 Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.
P?sel C et al. PLoS One 2012; 7 (12):e50293 Density gradient centrifugation compromises bone marrow mononuclear cell yield.
Biajoux V et al. J Transl Med 2012; 10:251 Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic Lupus erythematosus.
Grompone G et al. PLoS One 2012; 7 (12):e52493 Anti-inflammatory Lactobacillus rhamnosus CNCM I-3690 strain protects against oxidative stress and increases lifespan in Caenorhabditis elegans.
Ringpis GE et al. PLoS One 2012; 7 (12):e53492 Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.
2012; Vigorous response of human innate functioning IgM memory B cells upon infection by Neisseria gonorrhoeae.
Ma SD et al. J Virol 2011; 85 (1):165-77 A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas.
Schulz A et al. Haematologica 2011; 96 (3):408-16 Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2.
Imbeault M et al. J Virol 2011; 85 (5):2189-200 Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment.
Nagashima T et al. Am J Pathol 2011; 178 (1):222-32 Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help.
Scheible K et al. Vaccine 2011; 29 (11):2159-68 CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.
Iwata Y et al. Blood 2011; 117 (2):530-41 Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.
DiLillo DJ et al. J Immunol 2011; 186 (4):2643-54 B lymphocytes differentially influence acute and chronic allograft rejection in mice.
Rapoport AP et al. Blood 2011; 117 (3):788-97 Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma.
Caraux A et al. Immunology 2011; 132 (2):266-72 Mobilization of plasma cells in healthy individuals treated with granulocyte colony-stimulating factor for haematopoietic stem cell collection.
Huang Z et al. J Immunol 2011; 186 (6):3421-31 Involvement of CD226+ NK cells in immunopathogenesis of systemic lupus erythematosus.
Meek B et al. BMC Immunol 2011; 12:17 T cells fail to develop in the human skin-cell explants system; an inconvenient truth.
Qin H et al. Diabetes 2011; 60 (3):857-66 Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Zhang Y et al. Crit Care 2011; 15 (1):R70 Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Holderness J et al. PLoS One 2011; 6 (2):e17301 Polysaccharides isolated from A?a? fruit induce innate immune responses.
Lammers KM et al. Immunology 2011; 132 (3):432-40 Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease.
de Graaf MT et al. J Neurol 2011; 258 (8):1507-12 Addition of serum-containing medium to cerebrospinal fluid prevents cellular loss over time.
Walenda T et al. PLoS One 2011; 6 (3):e18012 Serum after autologous transplantation stimulates proliferation and expansion of human hematopoietic progenitor cells.
Collins A et al. Immunity 2011; 34 (3):303-14 RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.
Huntington ND et al. Proc Natl Acad Sci U S A 2011; 108 (15):6217-22 IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo.
Ratajczak J et al. Leukemia 2011; 25 (8):1278-85 Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells.
Gibbs KD Jr et al. Blood 2011; 117 (16):4226-33 Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.
Petterson T et al. Immunology 2011; 133 (1):84-93 Nucleotide-binding and oligomerization domain-like receptors and retinoic acid inducible gene-like receptors in human tonsillar T lymphocytes.
De Gobbi M et al. Epigenetics Chromatin 2011; 4 (1):9 Generation of bivalent chromatin domains during cell fate decisions.
Lee YS et al. BMC Cancer 2011; 11:225 T lymphocytes derived from human cord blood provide effective antitumor immunotherapy against a human tumor.
Lockridge JL et al. PLoS One 2011; 6 (6):e21701 Analysis of the CD1 antigen presenting system in humanized SCID mice.
Lindqvist CA et al. Immunology 2011; 133 (3):296-306 Both CD4+ FoxP3+ and CD4+ FoxP3- T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro.
Cui HD et al. Clin Exp Immunol 2011; 165 (2):163-71 Interleukin-10 receptor expression and signalling were down-regulated in CD4? T cells of lupus nephritis patients.
Boussaad I et al. J Virol 2011; 85 (15):7710-8 Wild-type measles virus interferes with short-term engraftment of human CD34+ hematopoietic progenitor cells.
Barbosa RR et al. PLoS One 2011; 6 (8):e22848 Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation.
Landrigan A et al. J Immunol 2011; 187 (6):3033-43 CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Garaud JC et al. PLoS One 2011; 6 (8):e23900 B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.
Onoe T et al. J Immunol 2011; 187 (7):3895-903 Human natural regulatory T cell development, suppressive function, and postthymic maturation in a humanized mouse model.
Villaudy J et al. PLoS Pathog 2011; 7 (9):e1002231 HTLV-1 propels thymic human T cell development in "human immune system" Rag2?/? gamma c?/? mice.
Sbiera S et al. PLoS One 2011; 6 (9):e24345 Influence of short-term glucocorticoid therapy on regulatory T cells in vivo.
Beck B et al. J Transl Med 2011; 9:151 Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
Wang C et al. BMC Immunol 2011; 12:53 Phenotype, effector function, and tissue localization of PD-1-expressing human follicular helper T cell subsets.
Mahnke YD et al. Vaccine 2011; 29 (47):8606-14 Age-related changes in durability and function of vaccine-elicited influenza-specific CD4(+) T-cell responses.
Garbe Y et al. BMC Cancer 2011; 11:410 Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.
Hilchey SP et al. Blood 2011; 118 (13):3591-602 Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation.
Hirbod T et al. PLoS One 2011; 6 (9):e25551 In situ distribution of HIV-binding CCR5 and C-type lectin receptors in the human endocervical mucosa.
Gotoh K et al. PLoS One 2011; 6 (10):e25490 Replication of Epstein-Barr virus primary infection in human tonsil tissue explants.
Jackson WM et al. J Cell Mol Med 2011; 15 (11):2377-88 Differentiation and regeneration potential of mesenchymal progenitor cells derived from traumatized muscle tissue.
Lafarge S et al. Clin Exp Immunol 2011; 166 (2):171-83 Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells.
Monticelli LA et al. Nat Immunol 2011; 12 (11):1045-54 Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
Li FJ et al. Blood 2011; 118 (18):4902-9 Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia.
Jung KC et al. J Exp Med 2011; 208 (12):2477-88 In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates.
Ivanovs A et al. J Exp Med 2011; 208 (12):2417-27 Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region.
Koreth J et al. N Engl J Med 2011; 365 (22):2055-66 Interleukin-2 and regulatory T cells in graft-versus-host disease.
Vuyyuru R et al. Proc Natl Acad Sci U S A 2011; 108 (51):20707-12 Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever.
Hayes GM et al. Leuk Res 2010; 34 (6):809-15 Isolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: validation of a simplified method suitable for multi-center clinical studies.
Ishmael SS et al. J Leukoc Biol 2010; 87 (2):291-300 Syk expression in peripheral blood leukocytes, CD34+ progenitors, and CD34-derived basophils.
Frenzel A et al. Blood 2010; 115 (5):995-1005 Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad.
Epel ES et al. Brain Behav Immun 2010; 24 (4):531-9 Dynamics of telomerase activity in response to acute psychological stress.
Shimura C et al. Am J Pathol 2010; 176 (1):227-37 Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin.
Kou PM et al. Acta Biomater 2010; 6 (7):2621-30 Validation of a high-throughput methodology to assess the effects of biomaterials on dendritic cell phenotype.
Van Landuyt KB et al. Arthritis Res Ther 2010; 12 (1):R15 Flow cytometric characterization of freshly isolated and culture expanded human synovial cell populations in patients with chronic arthritis.
Li L et al. Proc Natl Acad Sci U S A 2010; 107 (8):3505-10 Binding and uptake of H-ferritin are mediated by human transferrin receptor-1.
Ozaki Y et al. Clin Exp Immunol 2010; 159 (3):315-26 Decrease of blood dendritic cells and increase of tissue-infiltrating dendritic cells are involved in the induction of Sj?gren's syndrome but not in the maintenance.
Hunter PJ et al. Arthritis Rheum 2010; 62 (3):896-907 Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression.
Stroh T et al. PLoS One 2010; 5 (3):e9488 Combined pulse electroporation--a novel strategy for highly efficient transfection of human and mouse cells.
Sanz E et al. Proc Natl Acad Sci U S A 2010; 107 (13):5925-30 Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways.
Van Pottelberge GR et al. Respir Res 2010; 11:35 Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD.
Rajesh D et al. Hum Immunol 2010; 71 (6):551-9 Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rgammanull mice.
Bumb A et al. Nanotechnology 2010; 21 (17):175704 Preparation and characterization of a magnetic and optical dual-modality molecular probe.
Shaw J et al. Blood 2010; 115 (15):3051-7 Plasmacytoid dendritic cells regulate B-cell growth and differentiation via CD70.
Tu W et al. J Virol 2010; 84 (13):6527-35 Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus.
Vaithilingam V et al. Rev Diabet Stud 2010; 7 (1):62-73 The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets.
Onoe T et al. J Immunol 2010; 184 (12):6756-65 Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.
Moncrieffe H et al. J Immunol 2010; 185 (1):134-43 High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population.
Blimkie D et al. Cytometry A 2010; 77 (6):546-51 Identification of B cells through negative gating-An example of the MIFlowCyt standard applied.
Poulin LF et al. J Exp Med 2010; 207 (6):1261-71 Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.
Chen WC et al. Blood 2010; 115 (23):4778-86 In vivo targeting of B-cell lymphoma with glycan ligands of CD22.
Magnusson M et al. Rheumatology (Oxford) 2010; 49 (10):1911-9 Epstein-Barr virus in bone marrow of rheumatoid arthritis patients predicts response to rituximab treatment.
Holt N et al. Nat Biotechnol 2010; 28 (8):839-47 Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.
Moreno I et al. PLoS Negl Trop Dis 2010; 4 (7):e743 Kinetic analysis of ex vivo human blood infection by Leishmania.
Lay MK et al. Virology 2010; 406 (1):1-11 Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans.
Chen Z et al. Stem Cell Res 2010; 5 (3):212-25 Prospective isolation of clonogenic mantle cell lymphoma-initiating cells.
Steevels TA et al. Haematologica 2010; 95 (12):2005-12 Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblasts.
Lepone L et al. Clin Vaccine Immunol 2010; 17 (10):1507-16 Monofunctional and polyfunctional CD8+ T cell responses to human herpesvirus 8 lytic and latency proteins.
Abdel-Latif A et al. Exp Hematol 2010; 38 (12):1131-1142.e1 Evidence of mobilization of pluripotent stem cells into peripheral blood of patients with myocardial ischemia.
Rinderknecht CH et al. Immunology 2010; 131 (1):18-32 DM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II-associated invariant chain peptides via multiple mechanisms.
Meier D et al. Clin Exp Immunol 2010; 162 (1):138-45 Analysis of immune cells draining from the abdominal cavity as a novel tool to study intestinal transplant immunobiology.
Gertow J et al. Clin Exp Immunol 2010; 162 (1):146-55 Characterization of long-term mixed donor-donor chimerism after double cord blood transplantation.
Becker PD et al. PLoS One 2010; 5 (10) Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice.
Andr?s AM et al. PLoS Genet 2010; 6 (10):e1001157 Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.
Song J et al. Cell Host Microbe 2010; 8 (4):369-76 A mouse model for the human pathogen Salmonella typhi.
Qi Y et al. J Allergy Clin Immunol 2010; 126 (6):1260-6.e4 Human basophils express amphiregulin in response to T cell-derived IL-3.
Antonelli LR et al. Blood 2010; 116 (19):3818-27 Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome.
Liu C et al. Blood 2010; 116 (25):5518-27 Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation.
Pilling D et al. J Immunol Methods 2009; 351 (1-2):62-70 Improved serum-free culture conditions for the differentiation of human and murine fibrocytes.
Pilling D et al. PLoS One 2009; 4 (10):e7475 Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts.
Kawamata N et al. Respir Res 2009; 10:97 Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung.
Rieger L et al. Reprod Biol Endocrinol 2009; 7:132 Specific subsets of immune cells in human decidua differ between normal pregnancy and preeclampsia--a prospective observational study.
Chen Q et al. Proc Natl Acad Sci U S A 2009; 106 (51):21783-8 Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice.
2003; Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis.
2003; Expression of endocrine gland-derived vascular endothelial growth factor in ovarian carcinoma.
SDS
Sodium Azide.pdf
产品包装 报价 (¥)
¥ 3500
联系经销商
欣博盛生物科技有限公司
欣博盛生物科技有限公司
(全国热线) 4006-800-892 / (深圳) 0755-26755892 / (北京) 010-88594029 / (上海) 021-34613729 / (广州) 18024516375 / (香港) +852-69410778
http://www.neobioscience.com
genetex@neobioscience.com