形式
Liquid
存储溶液
PBS, 1% BSA, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Full length human recombinant protein of human DPP4 (NP_001926) produced in HEK293T cell.
纯化方式
Purified by affinity chromatography
From tissue culture supernatant
偶联
Unconjugated
RRID
AB_10731723
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
dipeptidyl peptidase 4 , ADABP , ADCP2 , CD26 , DPPIV , TP103
细胞定位
Apical cell membrane,Cell junction
功能与背景
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
数据库
研究领域
![Anti-CD26 antibody [11D7] used in Flow cytometry (FACS). GTX84602](/upload/website/prouct_img/small/GTX84602/GTX84602_477_FACS_w_23061420_604.webp "Anti-CD26 antibody [11D7] used in Flow cytometry (FACS). GTX84602")
![Anti-CD26 antibody [11D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84602](/upload/website/prouct_img/small/GTX84602/GTX84602_1148_ICCIF_w_23061420_280.webp "Anti-CD26 antibody [11D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84602")
![Anti-CD26 antibody [11D7] used in Western Blot (WB). GTX84602](/upload/website/prouct_img/small/GTX84602/GTX84602_4492_WB_w_23061420_449.webp "Anti-CD26 antibody [11D7] used in Western Blot (WB). GTX84602")
![Anti-CD26 antibody [11D7] used in IHC (Paraffin sections) (IHC-P). GTX84602](/upload/website/prouct_img/small/GTX84602/GTX84602_2895_IHC-P_w_23061420_871.webp "Anti-CD26 antibody [11D7] used in IHC (Paraffin sections) (IHC-P). GTX84602")
![Anti-CD26 antibody [11D7] used in Flow cytometry (FACS). GTX84602](/upload/website/prouct_img/normal/GTX84602/GTX84602_477_FACS_w_23061420_604.webp "Anti-CD26 antibody [11D7] used in Flow cytometry (FACS). GTX84602")
![Anti-CD26 antibody [11D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84602](/upload/website/prouct_img/normal/GTX84602/GTX84602_1148_ICCIF_w_23061420_280.webp "Anti-CD26 antibody [11D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84602")
![Anti-CD26 antibody [11D7] used in Western Blot (WB). GTX84602](/upload/website/prouct_img/normal/GTX84602/GTX84602_4492_WB_w_23061420_449.webp "Anti-CD26 antibody [11D7] used in Western Blot (WB). GTX84602")
![Anti-CD26 antibody [11D7] used in IHC (Paraffin sections) (IHC-P). GTX84602](/upload/website/prouct_img/normal/GTX84602/GTX84602_2895_IHC-P_w_23061420_871.webp "Anti-CD26 antibody [11D7] used in IHC (Paraffin sections) (IHC-P). GTX84602")
