产品说明
摘要
CD33, also known as Siglec-3 or gp67, is a 67 kDa glycosylated cell surface receptor that mediates cell-cell interactions and maintains immune cells in a resting state. Although CD33 is found on some lymphoid subsets, it is highly expressed on myeloid lineage cells, and is commonly used for the diagnosis of acute myeloid leukemia (AML). CD33 is an established target for therapy, with CD33-positive blasts detected in almost 90 percent of patients presenting with AML.
产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Human AML cells
纯化方式
Protein A purified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
CD33 , CD33 molecule , SIGLEC3 , p67
细胞定位
Cell membrane
数据库
研究领域
產品图片
![Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477](/templates/default/js/lightbox/images/loading.gif "Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477")
|
GTX00477 FACS Image
FACS analysis of human peripheral blood using GTX00477 CD33 antibody [WM53].
|
文献引用
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产品评论
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![Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477](/upload/website/prouct_img/small/GTX00477/GTX00477_20191028_FACS_1_w_23053121_372.webp "Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477")
![Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477](/upload/website/prouct_img/normal/GTX00477/GTX00477_20191028_FACS_1_w_23053121_372.webp "Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477")
