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CD44抗体 [8E2F3]

KO/KD Orthogonal
Anti-CD44 antibody [8E2F3] used in IHC (Paraffin sections) (IHC-P). GTX83114
Anti-CD44 antibody [8E2F3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83114
Anti-CD44 antibody [8E2F3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83114
Anti-CD44 antibody [8E2F3] used in Western Blot (WB). GTX83114
Anti-CD44 antibody [8E2F3] used in Flow cytometry (FACS). GTX83114
Anti-CD44 antibody [8E2F3] used in IHC (Paraffin sections) (IHC-P). GTX83114

目录号 GTX83114

文献引用 3

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 8E2F3

同种型

 IgG1

实验应用

 WB, ICC/IF, IHC-P, FACS, IP, ELISA

种属反应

 Human, Mouse, Pig
产品包装
100 μl (¥5300)
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产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:2000
ICC/IF 1:200-1:1000
IHC-P 1:200-1:1000
FACS 1:200-1:400
IP Assay dependent
ELISA Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

82 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

Ascitic fluid containing 0.03% sodium azide.

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

免疫原种属

Human

免疫原

The immunogen corresponding to a region within amino acids 628 and 699 of human CD44 expressed in E. Coli.

纯化方式

Unpurified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1

细胞定位

Cell membrane

功能与背景

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

数据库

研究领域

產品图片

Anti-CD44 antibody [8E2F3] used in IHC (Paraffin sections) (IHC-P). GTX83114

GTX83114 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX83114 CD44 antibody [8E2F3].

Anti-CD44 antibody [8E2F3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83114

GTX83114 ICC/IF Image

ICC/IF analysis of PANC-1 cells using GTX83114 CD44 antibody [8E2F3].
Green : CD44
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

Anti-CD44 antibody [8E2F3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83114

GTX83114 ICC/IF Image

ICC/IF analysis of methanol-fixed A431 (A), HeLa (B), PANC-1 (C) and EC (D) cells using GTX83114 CD44 antibody [8E2F3].
Green : CD44
Blue: DRAQ5 fluorescent DNA dye

Anti-CD44 antibody [8E2F3] used in Western Blot (WB). GTX83114

GTX83114 WB Image

WB analysis of HeLa (1) and HUVE-12(2) cell lysate using GTX83114 CD44 antibody [8E2F3].

Anti-CD44 antibody [8E2F3] used in Flow cytometry (FACS). GTX83114

GTX83114 FACS Image

FACS analysis of HeLa cells using GTX83114 CD44 antibody [8E2F3].
Right : CD44
Left : negative control

Anti-CD44 antibody [8E2F3] used in IHC (Paraffin sections) (IHC-P). GTX83114

GTX83114 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX83114 CD44 antibody [8E2F3].
Green : CD44
Blue: DRAQ5 fluorescent DNA

文献引用

Application Reference

Jhih-Ying Chi et al. Clin Transl Med. 2022; 12 (11) : e1099 Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosis
实验应用 : ICC/IF
种属反应 : Human
Hsiao YW et al. Clin Transl Med 2022; 12 (1) : e724 Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers.
实验应用 : WB, ICC/IF, IP
种属反应 : Human
Lin CL et al. Sci Rep 2019; 9 (1) : 14613 Topically Applied Cross-Linked Hyaluronan Attenuates the Formation of Spinal Epidural Fibrosis in a Swine Model of Laminectomy.
实验应用 : IHC-P
种属反应 : Pig
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产品包装 报价 (¥)
¥ 5300
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