CD44抗体
目录号 GTX102111
目录号 GTX102111
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宿主Rabbit
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克隆Polyclonal
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同种型IgG
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实验应用WB ICC/IF IHC-P IHC-Fr IP LCI
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种属反应Human, Rat, Rabbit
摘要
CD44 is an 82kDa multifunctional transmembrane glycoprotein involved in cell migration, proliferation, differentiation, and signaling pathways that mediate cell survival. It is involved in many malignancies as well as being recognized as a cancer stem cell marker. Importantly, it is expressed in leukocytes and is a marker of leukemia-initiating cells, being found to be critical in the pathogenesis of T cell acute lymphoblastic leukemia.