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CSB抗体 [N2C1], Internal

Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589
Anti-CSB antibody [N2C1], Internal used in Western Blot (WB). GTX104589
Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589
Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589
Anti-CSB antibody [N2C1], Internal used in Immunoprecipitation (IP). GTX104589
Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589
Anti-CSB antibody [N2C1], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX104589

目录号 GTX104589

文献引用 2

宿主

 Rabbit

克隆

 Polyclonal

同种型

 IgG

实验应用

 WB, ICC/IF, IHC-P, IP

种属反应

 Human, Mouse, Rat
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 CSB 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IP 1:100-1:500
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

168 kDa. ( Note )

预测种属反应

Bovine(>80% identity)

产品属性

形式

Liquid

存储溶液

PBS, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.69 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encompassing a sequence within the center region of human CSB. The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_1950219

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

ERCC excision repair 6, chromatin remodeling factor , ARMD5 , CKN2 , COFS , COFS1 , CSB , CSB-PGBD3 , POF11 , RAD26 , UVSS1

细胞定位

Nucleus

功能与背景

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. [provided by RefSeq]

数据库

研究领域

產品图片

Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589

GTX104589 IHC-P Image

CSB antibody [N2C1], Internal detects CSB protein at nucleus on mouse muscle by immunohistochemical analysis.
Sample: Paraffin-embedded mouse muscle.
CSB antibody [N2C1], Internal (GTX104589) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CSB antibody [N2C1], Internal used in Western Blot (WB). GTX104589

GTX104589 WB Image

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with CSB antibody [N2C1], Internal (GTX104589) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589

GTX104589 IHC-P Image

CSB antibody [N2C1], Internal detects CSB protein at nucleus on rat hind brain by immunohistochemical analysis.
Sample: Paraffin-embedded rat hind brain.
CSB antibody [N2C1], Internal (GTX104589) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589

GTX104589 IHC-P Image

CSB antibody [N2C1], Internal detects CSB protein at nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded rat brain.
CSB stained by CSB antibody [N2C1], Internal (GTX104589) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-CSB antibody [N2C1], Internal used in Immunoprecipitation (IP). GTX104589

GTX104589 IP Image

Immunoprecipitation of CSB protein from 293T whole cell extracts using 5 μg of CSB antibody [N2C1], Internal (GTX104589).
Western blot analysis was performed using CSB antibody [N2C1], Internal (GTX104589).
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

Anti-CSB antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX104589

GTX104589 IHC-P Image

CSB antibody [N2C1], Internal detects CSB protein at nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse brain.
CSB stained by CSB antibody [N2C1], Internal (GTX104589) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-CSB antibody [N2C1], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX104589

GTX104589 ICC/IF Image

CSB antibody [N2C1], Internal detects CSB protein at nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: CSB protein stained by CSB antibody [N2C1], Internal (GTX104589) diluted at 1:500.
Red: phalloidin, a cytoskeleton marker, diluted at 1:200.
Blue: Hoechst 33342 staining.
Scale bar = 10 μm.

文献引用

Application Reference

Wie M et al. NAR Cancer 2023; 5 (3) : zcad042 Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors.
Lin H et al. Nat Commun 2021; 12 (1) : 2461 IP6-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion.
种属反应 : Mouse
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产品包装 报价 (¥)
¥ 4000
¥ 1700
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