形式
Liquid
存储溶液
PBS, 0.1% BSA
保存剂
0.02% Sodium azide
存放说明
Store the peptide at -20ºC, stable for one year.
浓度
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
别名
C-X3-C Motif Chemokine Receptor 1 , Ccrl1 , Cmkbrl1 , Cmkdr1 , Gpr13 , Gprv28 , V28 , Cx3Cr1
功能与背景
CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
研究领域