形式
Liquid
存储溶液
0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
Batch dependent (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of CYP11A1. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography
偶联
Unconjugated
RRID
AB_2801476
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
别名
cytochrome P450 family 11 subfamily A member 1 , CYP11A , CYPXIA1 , P450SCC
细胞定位
Mitochondrion inner membrane
功能与背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
数据库
研究领域