形式
Liquid
存储溶液
0.1M Tris, 0.1M Glycine, 10% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the center region of human CtIP. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_1951655
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
RB binding protein 8, endonuclease , COM1 , CTIP , JWDS , RIM , SAE2 , SCKL2
细胞定位
Nucleus
功能与背景
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq]
数据库
研究领域
![Anti-CtIP antibody [C1C3] used in Western Blot (WB). GTX108857](/upload/website/prouct_img/small/GTX108857/GTX108857_40051_20190419_WB_w_23060120_692.webp "Anti-CtIP antibody [C1C3] used in Western Blot (WB). GTX108857")
![Anti-CtIP antibody [C1C3] used in Western Blot (WB). GTX108857](/upload/website/prouct_img/normal/GTX108857/GTX108857_40051_20190419_WB_w_23060120_692.webp "Anti-CtIP antibody [C1C3] used in Western Blot (WB). GTX108857")
