形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. Coli.
纯化方式
Protein G Purified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA
细胞定位
Cell membrane,Endoplasmic reticulum membrane,Endosome,Endosome membrane,Nucleus
功能与背景
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
数据库
研究领域
![Anti-EGFR (mutant) antibody [5G9B5] used in Flow cytometry (FACS). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_FACS_w_23061123_247.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Flow cytometry (FACS). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_WB_1_w_23061123_561.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in ELISA (ELISA). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_ELISA_w_23061123_227.webp "Anti-EGFR (mutant) antibody [5G9B5] used in ELISA (ELISA). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_WB_w_23061123_570.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_IHC-P_1_w_23061123_459.webp "Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766](/upload/website/prouct_img/small/GTX60766/GTX60766_20170912_IHC-P_w_23061123_877.webp "Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in Flow cytometry (FACS). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_FACS_w_23061123_247.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Flow cytometry (FACS). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_WB_1_w_23061123_561.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in ELISA (ELISA). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_ELISA_w_23061123_227.webp "Anti-EGFR (mutant) antibody [5G9B5] used in ELISA (ELISA). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_WB_w_23061123_570.webp "Anti-EGFR (mutant) antibody [5G9B5] used in Western Blot (WB). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_IHC-P_1_w_23061123_459.webp "Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766")
![Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766](/upload/website/prouct_img/normal/GTX60766/GTX60766_20170912_IHC-P_w_23061123_877.webp "Anti-EGFR (mutant) antibody [5G9B5] used in IHC (Paraffin sections) (IHC-P). GTX60766")
