形式
Liquid
存储溶液
PBS, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
Batch dependent (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
A synthesized peptide derived from human ERK2.
纯化方式
Purified by affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
mitogen-activated protein kinase 1 , ERK , ERK2 , ERT1 , MAPK1 , MAPK2 , P42MAPK , PRKM1 , PRKM2 , mitogenactivated protein kinase 1 , p38 , p40 , p41 , p41mapk , p42MAPK , P42 MAPK
细胞定位
Cytoplasm,Cytoskeleton,Spindle,Nucleus,Microtubule organizing center,Centrosome,Membrane,Caveola
功能与背景
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
数据库
研究领域
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/small/GTX00945/GTX00945_4000000169_20200313_WB_w_23053121_448.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/small/GTX00945/GTX00945_20200327_WB_1_w_23053121_922.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/small/GTX00945/GTX00945_20200327_WB_2_w_23053121_671.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/normal/GTX00945/GTX00945_4000000169_20200313_WB_w_23053121_448.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/normal/GTX00945/GTX00945_20200327_WB_1_w_23053121_922.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
![Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945](/upload/website/prouct_img/normal/GTX00945/GTX00945_20200327_WB_2_w_23053121_671.webp "Anti-ERK2 antibody [GT1183] used in Western Blot (WB). GTX00945")
