产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| 1:100-1:1000 |
| 1:100-1:1000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
Molt-4
产品属性
形式
Liquid
存储溶液
0.1M Tris, 0.1M Glycine, 10% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the center region of human FGD4. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_1950270
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
FYVE, RhoGEF and PH domain containing 4 , CMT4H , FRABP , ZFYVE6
细胞定位
Cytoplasm , cytoskeleton , Cell projection , filopodium
功能与背景
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq]
数据库
研究领域
產品图片
![Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859](/templates/default/js/lightbox/images/loading.gif "Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859")
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GTX109859 IHC-P Image
FGD4 antibody [N1N3] detects FGD4 protein at cytoplasm in human endometrial cancer by immunohistochemical analysis.
Sample: Paraffin-embedded human endometrial cancer.
FGD4 antibody [N1N3] (GTX109859) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX109859 ICC/IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using FGD4(GTX109859) antibody at 1:200 dilution.
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GTX109859 WB Image
Sample (30 ug of whole cell lysate)
A: Molt-4 (GTX27912)
7.5% SDS PAGE
GTX109859 diluted at 1:1000
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GTX109859 IHC-P Image
FGD4 antibody [N1N3] detects FGD4 protein at cytoplasm in human lung cancer by immunohistochemical analysis.
Sample: Paraffin-embedded human lung cancer.
FGD4 antibody [N1N3] (GTX109859) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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文献引用
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产品评论
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![Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859](/upload/website/prouct_img/small/GTX109859/GTX109859_40030_20150424_IHC_2_w_23060500_552.webp "Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859")
![Anti-FGD4 antibody [N1N3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX109859](/upload/website/prouct_img/small/GTX109859/GTX109859_IFA_w_23060500_885.webp "Anti-FGD4 antibody [N1N3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX109859")
![Anti-FGD4 antibody [N1N3] used in Western Blot (WB). GTX109859](/upload/website/prouct_img/small/GTX109859/GTX109859_WB_w_23060500_673.webp "Anti-FGD4 antibody [N1N3] used in Western Blot (WB). GTX109859")
![Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859](/upload/website/prouct_img/small/GTX109859/GTX109859_40030_20150424_IHC_w_23060500_338.webp "Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859")
![Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859](/upload/website/prouct_img/normal/GTX109859/GTX109859_40030_20150424_IHC_2_w_23060500_552.webp "Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859")
![Anti-FGD4 antibody [N1N3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX109859](/upload/website/prouct_img/normal/GTX109859/GTX109859_IFA_w_23060500_885.webp "Anti-FGD4 antibody [N1N3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX109859")
![Anti-FGD4 antibody [N1N3] used in Western Blot (WB). GTX109859](/upload/website/prouct_img/normal/GTX109859/GTX109859_WB_w_23060500_673.webp "Anti-FGD4 antibody [N1N3] used in Western Blot (WB). GTX109859")
![Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859](/upload/website/prouct_img/normal/GTX109859/GTX109859_40030_20150424_IHC_w_23060500_338.webp "Anti-FGD4 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX109859")
