产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品说明
This antibody was raised against human FGFR3 Intracellular domain.
预测种属反应
Bovine(>80% identity)
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
2 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Synthetic peptide encompassing a sequence within the Intracellular domain of human FGFR3. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
fibroblast growth factor receptor 3 , ACH , CD333 , CEK2 , HSFGFR3EX , JTK4
细胞定位
Cytoplasmic vesicle,Endoplasmic reticulum
功能与背景
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
数据库
研究领域
產品图片
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/templates/default/js/lightbox/images/loading.gif "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
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GTX637074 WB Image
Wild-type (WT) and FGFR3 knockout (KO) 293T cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FGFR3 antibody [HL1595] (GTX637074) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
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GTX637074 WB Image
Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FGFR3 antibody [HL1595] (GTX637074) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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GTX637074 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with FGFR3 antibody [HL1595] (GTX637074) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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文献引用
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产品评论
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![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/small/GTX637074/GTX637074_T-44725_20220715_WB_KO_watermark_22071823_690.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/small/GTX637074/GTX637074_44788_20221209_WB_D_C_22121123_945.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/small/GTX637074/GTX637074_44788_20220902_WB_TPM_watermark_22092119_691.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/normal/GTX637074/GTX637074_T-44725_20220715_WB_KO_watermark_22071823_690.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/normal/GTX637074/GTX637074_44788_20221209_WB_D_C_22121123_945.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
![Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074](/upload/website/prouct_img/normal/GTX637074/GTX637074_44788_20220902_WB_TPM_watermark_22092119_691.webp "Anti-FGFR3 antibody [HL1595] used in Western Blot (WB). GTX637074")
