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Fas Ligand抗体 [NOK-1] (生物素 biotin)
目录号 GTX01476-02
目录号 GTX01476-02
![Anti-Fas Ligand antibody [NOK-1] (Biotin) used in Flow cytometry (FCM). GTX01476-02](/upload/website/prouct_img/normal/GTX01476-02/GTX01476-02_20200428_FACS63_w_23053121_534.webp)
GTX01476-02 FCM Image
FACS analysis of human CD178 (Fas ligand) transfected cells using GTX01476-02 Fas Ligand antibody [NOK-1] (Biotin).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)
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![Anti-Fas Ligand antibody [NOK-1] (Biotin) used in Flow cytometry (FCM). GTX01476-02](/upload/website/prouct_img/middle/GTX01476-02/GTX01476-02_20200428_FACS63_w_23053121_534.webp){kind=small}
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宿主Mouse
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克隆Monoclonal
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克隆编号NOK-1
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同种型IgG1
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实验应用FCM
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种属反应Human
摘要
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.