GeneTex中国官方网站
  • China

GAPDH抗体 [GT239] (HRP)

Anti-GAPDH antibody [GT239] (HRP) used in Western Blot (WB). GTX627408-01
Anti-GAPDH antibody [GT239] (HRP) used in IHC (Paraffin sections) (IHC-P). GTX627408-01

目录号 GTX627408-01

文献引用 409

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 GT239

同种型

 IgG2b

实验应用

 WB, IHC-P

种属反应

 Human, Mouse, Rat, Hamster
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 GAPDH 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:5000-1:20000
IHC-P 1:100-1:1000
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

36 kDa. ( Note )

预测种属反应

Zebrafish, Rabbit, Sheep, Bovine, Cat, Dog, Chicken, Guinea pig, Pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)

产品属性

形式

Liquid

存储溶液

0.05M Tris, 0.15M NaCl, 1%BSA

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.62 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encompassing a sequence within the center region of human GAPDH. The exact sequence is proprietary.

纯化方式

Affinity purified by Protein G.

偶联

Horseradish peroxidase(HRP)

RRID

AB_2888014

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

glyceraldehyde-3-phosphate dehydrogenase , G3PD , GAPD , HEL-S-162eP

细胞定位

Cytoplasm , perinuclear region , Membrane

功能与背景

The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. [provided by RefSeq]

数据库

研究领域

產品图片

Anti-GAPDH antibody [GT239] (HRP) used in Western Blot (WB). GTX627408-01

GTX627408-01 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (HRP) (GTX627408-01) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-GAPDH antibody [GT239] (HRP) used in IHC (Paraffin sections) (IHC-P). GTX627408-01

GTX627408-01 IHC-P Image

GAPDH antibody [GT239] (HRP) detects GAPDH antibody protein at cytoplasm in rat testis by immunohistochemical analysis.
Sample: Paraffin-embedded rat testis.
GAPDH antibody [GT239] (HRP) (GTX627408-01) diluted at 1:200.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

文献引用

Application Reference

Zengel J et al. Nat Methods 2023; 20 (7) : 1070-1081 Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.

Clone Reference

Escalante-Covarrubias Q et al. Nat Commun 2023; 14 (1):1685 Time-of-day defines NAD(+) efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice.
实验应用 : WB
种属反应 : Mouse
Shilts J et al. PLoS Biol 2023; 21 (2):e3001959 LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Despic V et al. Nature 2023; 614 (7947):358-366 mRNA ageing shapes the Cap2 methylome in mammalian mRNA.
Quiles JM et al. Sci Signal 2023; 16 (770):eabo4457 Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy.
显示更多 +
我要回报文献

产品评论

目前没有使用 GAPDH antibody [GT239] (HRP) (GTX627408-01) 的产品评论被收录。快发表第一篇产品评论吧！
我要评论产品
Application Reference
Zengel J et al. Nat Methods 2023; 20 (7):1070-1081 Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.
S?nchez-Ram?rez E et al. J Cell Biol 2022; 221 (12) Coordinated metabolic transitions and gene expression by NAD+ during adipogenesis.
实验应用 : WB
种属反应 : Human
Ma S et al. PLoS One 2022; 17 (9):e0274618 Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction.
Taura M et al. Proc Natl Acad Sci U S A 2022; 119 (20):e2011665119 APOBEC3A regulates transcription from interferon-stimulated response elements.
Revollo L et al. Blood 2022; 139 (1):104-117 The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.
Willis A et al. Mol Neurobiol 2022; Enzymatic Degradation of Cortical Perineuronal Nets Reverses GABAergic Interneuron Maturation.
实验应用 : WB
种属反应 : Mouse
Antonino Asaro et al. J Cell Sci 2021; 134 (20) ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
实验应用 : WB
种属反应 : Mouse, Hamster
Revollo L. et al. bioRxiv 2021; (Epub) The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.
实验应用 : WB
种属反应 : Human
Klatt D et al. Cells 2020; 9 (10) Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment.
实验应用 : WB
种属反应 : Human
Wang L et al. Proc Natl Acad Sci U S A 2020; 117 (1):563-572 A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
Kim DJ et al. J Virol 2020; 94 (22) RUNX Binding Sites Are Enriched in Herpesvirus Genomes, and RUNX1 Overexpression Leads to Herpes Simplex Virus 1 Suppression.
实验应用 : WB
种属反应 : Mouse
Phatarpekar PV et al. J Cell Biol 2020; 219 (11) The septin cytoskeleton regulates natural killer cell lytic granule release.
实验应用 : WB
种属反应 : Human
Tran DT et al. Diabetes 2020; 69 (8):1723-1734 Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
实验应用 : WB
种属反应 : Human
Lu RA et al. Front Pharmacol 2020; 11:469 Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins.
实验应用 : WB
种属反应 : Human
Alex G. Johnson et al. bioRxiv 2019; (Epub) A memory of RPS25 loss drives resistance phenotypes.
实验应用 : WB
种属反应 : Human
Ma S et al. Am J Physiol Renal Physiol 2019; 317 (3):F623-F631 Knockout of TRPA1 exacerbates angiotensin II-induced kidney injury.
实验应用 : WB
种属反应 : Mouse
Taura M et al. Proc Natl Acad Sci U S A 2019; 116 (6):2282-2289 Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat.
实验应用 : WB
种属反应 : Human
Jessen TN et al. Exp Cell Res 2019; 374 (1):128-139 VANGL2 protein stability is regulated by integrin αv and the extracellular matrix.
实验应用 : WB
种属反应 : Human
Jessen TN et al. Exp Cell Res 2017; 361 (2):265-276 VANGL2 interacts with integrin αv to regulate matrix metalloproteinase activity and cell adhesion to the extracellular matrix.
Olabisi OA et al. Proc Natl Acad Sci U S A 2016; 113 (4):830-7 APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.
实验应用 : WB
种属反应 : Human
Schrecengost RS et al. Mol Cancer Res 2015; 13 (12):1591-601 Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.
实验应用 : WB
种属反应 : Human
Heneghan JF et al. Am J Physiol Cell Physiol 2015; 309 (5):C332-47 BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins.
实验应用 : WB
种属反应 : Human
Clone Reference
Ferdous S et al. Front Cell Neurosci 2023; 17:1104592 Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure.
Cheng H et al. Evid Based Complement Alternat Med 2023; 2023:8673136 Study on Neuroprotective Mechanism of Houshiheisan in Ischemic Stroke Based on Transcriptomics and Experimental Verification.
Arimoto KI et al. Nat Commun 2023; 14 (1):251 Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.
Sych K et al. J Mol Med (Berl) 2023; 101 (2023/1/2):151-169 Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro.
Tsui KH et al. Aging (Albany NY) 2023; 15 (1):246-260 Mitoquinone shifts energy metabolism to reduce ROS-induced oxeiptosis in female granulosa cells and mouse oocytes.
Jiang B et al. Mol Med Rep 2023; 27 (2) Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Escalante-Covarrubias Q et al. Nat Commun 2023; 14 (1):1685 Time-of-day defines NAD(+) efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice.
实验应用 : WB
种属反应 : Mouse
Shilts J et al. PLoS Biol 2023; 21 (2):e3001959 LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Despic V et al. Nature 2023; 614 (7947):358-366 mRNA ageing shapes the Cap2 methylome in mammalian mRNA.
Quiles JM et al. Sci Signal 2023; 16 (770):eabo4457 Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy.
Natascha Leitner et al. BMC Vet Res 2022; 18 (1):221 Lipid droplet dynamics in healthy and pyometra-affected canine endometrium.
Potier B et al. Int. J. Mol. Sci. 2022; 23 (2):592 DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.
Lopez-Toledo G et al. Front Aging Neurosci 2022; 14:921573 Patient-Derived Fibroblasts With Presenilin-1 Mutations, That Model Aspects of Alzheimer's Disease Pathology, Constitute a Potential Object for Early Diagnosis.
Leitner N et al. Vet Res Commun 2022; 46 (4):1175-1193 Lipid droplets and perilipins in canine osteosarcoma. Investigations on tumor tissue, 2D and 3D cell culture models.
Usher JL et al. EMBO Rep 2022; 23 (12):e53552 Parkin drives pS65-Ub turnover independently of canonical autophagy in Drosophila.
Renaud E et al. Mol Cancer 2022; 21 (1):195 Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis.
Peters CE et al. Nat Commun 2022; 13 (1):5282 Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Shebl B et al. JCI Insight 2022; 7 (17) Targeting BCL-XL in fibrolamellar hepatocellular carcinoma.
Guo L et al. Mol Cancer Ther 2022; 21 (5):740-750 Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells.
Chadelle L et al. Cancer Lett 2022; 526:112-130 PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells.
Huang CY et al. J Hepatocell Carcinoma 2022; 9:1385-1401 Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses.
Yousefi M et al. PLoS Pathog 2022; 18 (8):e1010763 TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.
Ferguson KM et al. Front Cell Dev Biol 2022; 10:983097 Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells.
Yeh CT et al. Biomedicines 2022; 10 (11) Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo.
Wu MH et al. Biomedicines 2022; 10 (10) Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo.
Wu CE et al. Am J Cancer Res 2022; 12 (9):4399-4410 In vitro and in vivo study of GSK2830371 and RG7388 combination in liver adenocarcinoma.
Guyard V et al. J Cell Biol 2022; 221 (9) ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER-mitochondria contact sites.
Zhang L et al. J Neuroendocrinol 2022; 34 (9):e13164 Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression.
Yi-Ing Chen et al. Nat Commun 2022; 13 (1):2945 Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Xue-Feng Feng et al. Front Pharmacol 2022; 13:851746 Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats.
Alexandra G Moyzis et al. Cells 2022; 11 (9) Mcl-1 Differentially Regulates Autophagy in Response to Changes in Energy Status and Mitochondrial Damage.
Yueh-Hua Chung et al. Sci Rep 2022; 12 (1):6955 MiR-26a-5p as a useful therapeutic target for upper tract urothelial carcinoma by regulating WNT5A/β-catenin signaling.
Shwetha Shivaprasad et al. PLoS Pathog 2022; 18 (4):e1010163 Loquacious modulates flaviviral RNA replication in mosquito cells.
Yu-Hsuan Hung et al. Int J Mol Sci 2022; 23 (5) Semaphorin 6C Suppresses Proliferation of Pancreatic Cancer Cells via Inhibition of the AKT/GSK3/β-Catenin/Cyclin D1 Pathway.
Brigitte Potier et al. Int J Mol Sci 2022; 23 (2) DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.
Tram Anh Tran et al. J Biol Chem 2022; 298 (2):101515 Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival.
Faqi Wang et al. Front Aging Neurosci 2022; 14:814560 Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment.
Hongmin Liang et al. Front Immunol 2022; 13:832458 Pyolysin of Trueperella pyogenes Induces Pyroptosis and IL-1β Release in Murine Macrophages Through Potassium/NLRP3/Caspase-1/Gasdermin D Pathway.
He L et al. EMBO Mol Med 2022;:e14990 CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
Wang LY et al. Int J Mol Sci 2022; 23 (5) The Anti-Proliferative and Apoptotic Effects of Rutaecarpine on Human Esophageal Squamous Cell Carcinoma Cell Line CE81T/VGH In Vitro and In Vivo.
Magalh?es AC et al. Pathogens 2022; 11 (3) InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.
Lai KC et al. J Cachexia Sarcopenia Muscle 2022; IFIT2-depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice.
Dom?nguez-Sala E et al. Brain Struct Funct 2022; (Epub) Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction.
Brettrager EJ et al. Sci Rep 2022; 12 (1):1625 Sulfotransferase 4A1 activity facilitates sulfate-dependent cellular protection to oxidative stress.
Tracy TE et al. Cell 2022; 185 (4):712-728.e14 Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Narayanan D et al. Virus Genes 2022; (Epub) Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment.
Oom AL et al. Mol Cell Proteomics 2022;:100194 Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression.
Lai Z.Y. et al. Int. J. Mol. Sci. 2021; 22 (16):8784 Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor.
Molinar-Inglis O. et al. bioRxiv 2021; (Epub) aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis.
Biomedical Journal 2021; (Epub) Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
Chien HM et al. Commun Chem 2021; 4 (1):111 Nanoscopic investigation of C9orf72 poly-GA oligomers on nuclear membrane disruption by a photoinducible platform.
Cheng TC et al. J Food Drug Anal 2021; 29 (4):622-637 Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.
Olivia Molinar-Inglis et al. Proc Natl Acad Sci U S A 2021; 118 (49) aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.
Karen Dunbar et al. Cell Mol Gastroenterol Hepatol 2021; 11 (2):465-489 Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1.
Wen-Fang Tang et al. Biomed J 2021; 44 (3):293-303 Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
Ke Zhang et al. Sci Adv 2021; 7 (6) Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.
Jeanee Bullock et al. Invest Ophthalmol Vis Sci 2021; 62 (2):30 Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R).
Katherine M Almasy et al. bioRxiv 2021; Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs.
Gareth A Roberts et al. Nat Cell Biol 2021; 23 (8):834-845 Dissecting OCT4 defines the role of nucleosome binding in pluripotency.
Yanqi Xie et al. Mol Cancer Ther 2021; 20 (10):1893-1903 Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor.
Tung Chao et al. Autophagy 2021; 17 (11):3444-3460 Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.
Caini Fan et al. Int J Mol Sci 2021; 22 (8) NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium.
Laura Martin-Sancho et al. Mol Cell 2021; Functional landscape of SARS-CoV-2 cellular restriction.
Raul Bardini Bressan et al. Cell Stem Cell 2021; 28 (5):877-893.e9 Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants.
Mar?a ?ngeles Marqu?s-Torrej?n et al. Nat Commun 2021; 12 (1):2594 LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Katherine M Almasy et al. Mol Cell Proteomics 2021;:100120 Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.
Chiao-En Wu et al. Cancers (Basel) 2021; 13 (15) WIP1 Inhibition by GSK2830371 Potentiates HDM201 through Enhanced p53 Phosphorylation and Activation in Liver Adenocarcinoma Cells.
Zih-Yin Lai et al. Int J Mol Sci 2021; 22 (16) Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor.
Shuyin Bao et al. Front Pharmacol 2021; 12:656220 Agriophyllum Oligosaccharides Ameliorate Diabetic Insulin Resistance Through INS-R/IRS/Glut4-Mediated Insulin Pathway in db/db Mice and MIN6 Cells.
Nina-Naomi Kreis et al. Cells 2021; 10 (9) Functional Analysis of p21Cip1/CDKN1A and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia.
Yueh-Ming Shyu et al. Int J Mol Sci 2021; 22 (18)
Hong Xiang et al. MAbs 2021; 13 (1):1981202 Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer.
Elena Porc? et al. iScience 2021; 24 (11):103350 The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics.
Wang LC et al. Front Aging Neurosci 2021; 13:741168 Somatosensory Cortical Electrical Stimulation After Reperfusion Attenuates Ischemia/Reperfusion Injury of Rat Brain.
Moon HH et al. Cancers (Basel) 2021; 13 (22) Mitotic Centromere-Associated Kinesin (MCAK/KIF2C) Regulates Cell Migration and Invasion by Modulating Microtubule Dynamics and Focal Adhesion Turnover.
Garcia JD et al. Cell Rep 2021; 37 (12):110142 Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity.
Ren K et al. Virol J 2021; 18 (1):256 IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3.
De Sarkar N et al. JCI Insight 2021; 6 (23) Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
Wang Y et al. Nature 2021; 599 (7883):136-140 SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Mohseni YR et al. Eur J Immunol 2021; 51 (10):2522-2530 Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.
McCarthy GM et al. Dis Model Mech 2021; 14 (8) Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease.
Yao CL et al. Aging (Albany NY) 2021; 13 (15):19878-19893 CCL2 associated with CD38 expression during ex vivo expansion in human cord blood-derived hematopoietic stem cells.
Poobalasingam T et al. J Neurochem 2021; (Epub) The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons.
Rada CC et al. Sci Signal 2021; 14 (698):eabc1044 Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption.
Frydas A et al. Neurobiol Aging 2021; (Epub) Genetic variants in progranulin upstream open reading frames increase downstream protein expression.
Yenerall P et al. Cancer Res 2021; 81 (18):4685-4695 Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.
Kwon J et al. Cell Mol Neurobiol 2021; (Epub) Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells.
Chakraborty P et al. Nat Commun 2021; 12 (1):4126 DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination.
Harley J et al. Brain Commun 2021; 3 (3):fcab166 TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain.
Lin CC et al. Nat Commun 2021; 12 (1):3878 Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation.
Lee TT et al. Aging Cell 2021; 20 (6):e13379 Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila.
Michelis G et al. J Neurochem 2021; Pigment epithelium-derived factor (PEDF) and derived peptides promote survival and differentiation of photoreceptors and induce neurite-outgrowth in amacrine neurons.
Maiques O et al. Br J Cancer 2021; A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
?vila-Rosales OS et al. Toxics 2021; 9 (6) Daytime Restricted Feeding Modifies the Temporal Expression of CYP1A1 and Attenuated Damage Induced by Benzo[a]pyrene in Rat Liver When Administered before CYP1A1 Acrophase.
Shen CH et al. Front Cell Dev Biol 2021; 9:642625 ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation.
Park SH et al. PLoS Pathog 2021; 17 (5):e1009519 Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.
Chen XQ et al. Alzheimers Res Ther 2021; 13 (1):59 Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
Baxley RM et al. Nat Commun 2021; 12 (1):1626 Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening.
Sonnenberg SB et al. J Cell Sci 2021; 134 (4) The 5-HT4 receptor interacts with adhesion molecule L1 to modulate morphogenic signaling in neurons.
Deffieu MS et al. Sci Adv 2021; 7 (2) Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway.
Wu J et al. J Biol Chem 2021;:100496 Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling.
Arakaki AKS et al. J Cell Sci 2021; (Epub) α-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.
Chang-Ching Weng et al. Materials & Design 2020; 197:109230 Design and fabrication of cell-targeted, dual drug-loaded nanoparticles with pH-controlled drug release and near-infrared light-induced photothermal effects.
Wangta Liu et al. Oxidative Medicine and Cellular Longevity 2020; 2020:Article ID 5167292 The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling.
Alexandra G Moyzis et al. J Mol Cell Cardiol 2020; 146:109-120 Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
Hueng-Chuen Fan et al. Int J Mol Sci 2020; 21 (22) Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis.
Tsong-Hai Lee et al. Cell Commun Signal 2020; 18 (1):185 The COX-2-derived PGE2 autocrine contributes to bradykinin-induced matrix metalloproteinase-9 expression and astrocytic migration via STAT3 signaling.
Zhentian Li et al. PLoS One 2020; 15 (11):e0235998 Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation.
Jonathan P Davies et al. ACS Infect Dis 2020; 6 (12):3174-3189 Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.
Soula M et al. Nat Chem Biol 2020; 16 (12):1351-1360 Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Lai PL et al. Oncol Lett 2020; 20 (3):2937-2945 Selection of a malignant subpopulation from a colorectal cancer cell line.
Agote-Aran A et al. EMBO J 2020; 39 (20):e104467 Spatial control of nucleoporin condensation by fragile X-related proteins.
Glaesel K et al. Int J Mol Sci 2020; 21 (11) miR-129-5p and miR-130a-3p Regulate VEGFR-2 Expression in Sensory and Motor Neurons during Development.
Hight SK et al. Neoplasia 2020; 22 (8):294-310 An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.
Chiang AJ et al. Biomolecules 2020; 11 (1) UBE2C Drives Human Cervical Cancer Progression and Is Positively Modulated by mTOR.
McMichael BD et al. J Appl Toxicol 2020; (Epub) Long-term arsenic exposure impairs differentiation in mouse embryonal stem cells.
Shin JE et al. Nutrients 2020; 12 (11) Soluble Whey Protein Hydrolysate Ameliorates Muscle Atrophy Induced by Immobilization via Regulating the PI3K/Akt Pathway in C57BL/6 Mice.
Zhou X et al. Nat Commun 2020; 11 (1):6088 Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Liu W et al. Oxid Med Cell Longev 2020; 2020:5167292 The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling.
Or CR et al. Int J Mol Sci 2020; 21 (5) Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling.
Sarkar A et al. Mol Cell Biochem 2020; Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies.
Guarecuco R et al. Sci Adv 2020; 6 (41) Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Haupt M et al. Neuropharmacology 2020; 181:108357 Lithium enhances post-stroke blood-brain barrier integrity, activates the MAPK/ERK1/2 pathway and alters immune cell migration in mice.
Schuster-Gaul S et al. JCI Insight 2020; 5 (2) ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Yun SI et al. Cancers (Basel) 2020; 12 (1) Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Lee M et al. J Cell Biol 2020; 219 (2) Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.
Nicholas DA et al. Sci Rep 2020; 10 (1):13063 GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes.
Huang S et al. J Cell Mol Med 2020; 24 (19):11133-11145 Up-regulated acylglycerol kinase (AGK) expression associates with gastric cancer progression through the formation of a novel YAP1-AGK-positive loop.
Young AM et al. Mol Biol Cell 2020; 31 (15):1551-1560 BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins.
Qu Z et al. Biotechnol Lett 2020; 42 (12):2489-2500 Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway.
Rajgor D et al. Cell Rep 2020; 31 (12):107785 Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation.
Liang W et al. Aging Cell 2020; 19 (8):e13187 Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart.
Pennycook BR et al. Nat Commun 2020; 11 (1):3503 E2F-dependent transcription determines replication capacity and S phase length.
Navarro-Mabarak C et al. Brain Res Bull 2020; 163:57-64 Neuroinflammation is able to downregulate cytochrome P450 epoxygenases 2J3 and 2C11 in the rat brain.
Gella A et al. Front Cell Dev Biol 2020; 8:660 Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Sheets JN et al. Oncotarget 2020; 11 (24):2290-2301 SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model.
Bogucka K et al. Elife 2020; 9 ERK3/MAPK6 controls IL-8 production and chemotaxis.
Chen PL et al. Nat Commun 2020; 11 (1):2592 Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster.
Yu TJ et al. Biomolecules 2020; 10 (5) Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells.
Duong P et al. Biol Sex Differ 2020; 11 (1):12 Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment.
Bao S et al. J Ethnopharmacol 2020; 257:112863 Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-帠/Glut4 signal pathway.
Valls-Lacalle L et al. Biomolecules 2020; 10 (4) Connexin 43 Deficiency Is Associated with Reduced Myocardial Scar Size and Attenuated TGF帣1 Signaling after Transient Coronary Occlusion in Conditional Knock-Out Mice.
Bettina B?ttcher et al. Front Microbiol 2020; 11:794 The Transcription Factor Stp2 Is Important for Candida albicans Biofilm Establishment and Sustainability.
Robertson R et al. Am J Pathol 2020; 190 (3):554-562 BAG3P215L/KO Mice as a Model of BAG3P209L Myofibrillar Myopathy.
Gasilina A et al. PLoS One 2020; 15 (3):e0229801 IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.
Pedersen H et al. Int J Mol Sci 2020; 21 (5) Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells.
Baltes F et al. Biochim Biophys Acta Mol Cell Res 2020; 1867 (5):118663 β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters.
Sarkar A et al. Haematologica 2020; (Epub) Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Dragan M et al. Cell Death Dis 2020; 11 (2):106 G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer.
Vibhuti Vyas et al. FASEB 2019; (Epub) Adiponectin links maternal metabolism to uterine contractility.
Arantxa Agote-Ar?n et al. bioRxiv 2019; (Epub) Spatial control of nucleoporin assembly by Fragile X-related proteins.
YingGuo et al. CJD 2019; (Epub) MicroRNA-15a inhibits GLUT4 translocation and impairs glucose metabolism in L6 skeletal muscle via targeting of VAP-A.
Berenice M?rquez-Valadez et al. Front. Neurosci. 2019; (Epub) The Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist.
Munshi A et al. Stem Cell Res Ther 2019; 10 (1):401 A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles.
Nguyen HD et al. Cancers (Basel) 2019; 11 (12) The α9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration.
Li W et al. J Biol Chem 2019; 294 (15):5914-5922 Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells.
Tenkorang MAA et al. Endocrinology 2019; 160 (4):947-963 NADPH Oxidase Mediates Membrane Androgen Receptor-Induced Neurodegeneration.
Xia X et al. ACS Chem Biol 2019; 14 (5):994-1001 Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1.
Diep J et al. Nat Microbiol 2019; 4 (12):2523-2537 Enterovirus pathogenesis requires the host methyltransferase SETD3.
Wildner JM et al. Cells 2019; 8 (12) RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.
Bayraktar EC et al. Proc Natl Acad Sci U S A 2019; 116 (1):303-312 MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo.
Gama Sosa MA et al. Acta Neuropathol Commun 2019; 7 (1):6 Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.
Nagano M et al. Commun Biol 2019; 2 (1):419 Rab5-mediated endosome formation is regulated at the trans-Golgi network.
Wantoch von Rekowski K et al. Biomolecules 2019; 9 (12)
Galmozzi A et al. Nature 2019; 576 (7785):138-142 PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Botrugno OA et al. Haematologica 2019; (Epub) ATR addiction in multiple myeloma: synthetic lethal approaches exploiting established therapies.
Majer O et al. Nature 2019; 575 (7782):371-374 Release from UNC93B1 reinforces the compartmentalized activation of select TLRs.
Choquet K et al. J Biol Chem 2019; 294 (18):7445-7459 Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200.
Nagano M et al. Commun Biol 2019; 2:419 Rab5-mediated endosome formation is regulated at the trans-Golgi network.
Lin ST et al. Front Physiol 2019; 10:1308 Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells.
Ritter A et al. Cells 2019; 8 (10) Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.
Schmidlin T et al. Cell Syst 2019; 9 (4):366-374.e5 High-Throughput Assessment of Kinome-wide Activation States.
Ogola BO et al. Front Endocrinol (Lausanne) 2019; 10:586 G Protein-Coupled Estrogen Receptor Protects From Angiotensin II-Induced Increases in Pulse Pressure and Oxidative Stress.
Gatz C et al. Front Neurol 2019; 10:562 Identification of Cellular Pathogenicity Markers for SIL1 Mutations Linked to Marinesco-Sj?gren Syndrome.
Hu Y et al. Mol Reprod Dev 2019; MiR-8-3p regulates hyperthermia-induced lactate secretion by targeting PPP2R5B in boar Sertoli cells.
Majer O et al. Nature 2019; UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
Akimoto Y et al. Am J Physiol Renal Physiol 2019; O-GlcNAcylation and Phosphorylation of β-Actin Serine199 in Diabetic Nephropathy.
Bolea I et al. Elife 2019; 8 Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome.
Peiris MN et al. Haematologica 2019; (Epub) Oncogenic fusion protein BCR-FGFR1 requires BCR-mediated oligomerization and chaperonin Hsp90 for activation.
Kreis NN et al. Cancers (Basel) 2019; 11 (7) Function of p21 (Cip1/Waf1/CDKN1A) in Migration and Invasion of Cancer and Trophoblastic Cells.
Andreazza S et al. Nat Commun 2019; 10 (1):3280 Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila.
Fantini V et al. Cells 2019; 8 (8) Bioink Composition and Printing Parameters for 3D Modeling Neural Tissue.
Inserte J et al. J Mol Cell Cardiol 2019; 133:164-173 High-fat diet improves tolerance to myocardial ischemia by delaying normalization of intracellular PH at reperfusion.
Ham S et al. Mol Cells 2019; 42 (6):480-494 Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates.
Cheng YP et al. Int J Mol Sci 2019; 20 (13) Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells.
Woodall BP et al. JCI Insight 2019; 5 Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice.
Lampert MA et al. Autophagy 2019; 15 (7):1182-1198 BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation.
Goren I et al. Nitric Oxide 2019; 87:31-42 Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
Chou CK et al. Environ Toxicol 2019; 34 (4):401-414 Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes.
Bang BR et al. J Virol 2019; (Epub) Regulation of HCV infection by Cellular Retinoic Acid Binding Proteins through the modulation of lipid droplet abundance.
Brifault C et al. Glia 2019; (Epub) LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing.
Tseng HW et al. Cancers (Basel) 2019; 11 (2) * treatment suppresses melanoma cell growth and motility through modulation of microrna expression.
Garcia-Bermudez J et al. Nature 2019; 567 (7746):118-122 Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Hu CM et al. Cell Metab 2019; (Epub) High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.
Takeuchi S et al. Am J Pathol 2019; 189 (2):391-404 Elevated Membrane Cholesterol Disrupts Lysosomal Degradation to Induce β-Amyloid Accumulation: The Potential Mechanism Underlying Augmentation of β-Amyloid Pathology by Type 2 Diabetes Mellitus.
Erol C. Bayraktar et al. bioRxiv 2018; (Epub) MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo.
Olivia Majer et al. bioRxiv 2018; (Epub) Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity.
Olivia Majer et al. bioRxiv 2018; (Epub) An essential checkpoint for TLR9 signaling is release from 1 Unc93b1 in endosomes.
SHIJIE HE et al. bioRxiv 2018; (Epub) The tumor suppressor p53 promotes carcinoma invasion and collective cellular migration.
Ou Y et al. Int J Clin Exp Pathol 2018; 11 (6):3052-3060 Silencing profilin-1 confers protection from oxLDL injury in human vascular endothelial cells.
Lu Y et al. Neural Regeneration Research 2018; 13 (7):1195-1203 Houshiheisan and its components promote axon regeneration after ischemic brain injury.
AshleighWillis et al. Journal of Neuroscience Methods 2018; (Epub) Distortion of protein analysis in primary neuronal cultures by serum albumin from culture medium: a methodological approach to improve target protein quantification.
Miscianinov V. et al. Molecular Therapy 2018; (Epub) MicroRNA-148b targets the TGF-β pathway to regulate angiogenesis and endothelialto-mesenchymal transition during skin wound healing.
Tian L et al. Hindawi 2018; (Epub) Electroacupuncture at ST-36 protects interstitial cells of Cajal via sustaining heme oxygenase-1 positive M2 macrophages in the stomach of diabetic mice.
Arakaki AKS et al. J Biol Chem 2018; 293 (9):3350-3362 The α-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling.
Le CT et al. PLoS One 2018; 13 (2):e0192146 LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate-G-protein couple receptor 91 (GPR91) pathway in mice.
Sung K et al. J Neurosci 2018; 38 (14):3394-3413 Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception.
Chou CK et al. Int J Mol Sci 2018; 19 (7) Ethyl Acetate Extract of Scindapsus Cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells Through Modulating ER Stress.
Tripurani SK et al. Mol Biol Cell 2018; 29 (22):2784-2799 Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development.
Chen YL et al. Am J Cancer Res 2018; 8 (12):2548-2563 Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.
Jakubzig B et al. Cancers (Basel) 2018; 10 (12) Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells-Deciphering Novel Potential Targets for a Cell Sensitization.
Ponert JM et al. Molecules 2018; 23 (10) Unfractionated and Low Molecular Weight * Reduce Platelet Induced Epithelial-Mesenchymal Transition in Pancreatic and Prostate Cancer Cells.
Chakraborty P et al. Nat Commun 2018; 9 (1):4346 DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing.
Tiwari PM et al. Nat Commun 2018; 9 (1):3999 Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection.
Rodrigues ACZ et al. Acta Physiol (Oxf) 2018;:e13195 The sympathetic nervous system regulates skeletal muscle motor innervation and acetylcholine receptor stability.
Snyder B et al. Horm Behav 2018; 106:62-73 Androgens modulate chronic intermittent hypoxia effects on brain and behavior.
Baek JH et al. Am J Pathol 2018; (Epub) deletion of the mitochondrial complex-iv cofactor heme a/farnesyltransferase causes focal segmental glomerulosclerosis and * response.
Ohta S et al. Mol Cell Proteomics 2018; (Epub) Quantitative proteomics of the mitotic chromosome scaffold reveals the association of BAZ1B with chromosomal axes.
Grimsey NJ et al. Cell Rep 2018; 24 (12):3312-3323.e5 A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.
Lai CY et al. J Neurosci 2018; 38 (43):9160-9174 Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia.
Zhang Q et al. Oncol Rep 2018; (Epub) * improves adoptive carbonic anhydrase-ix-specific chimeric antigen receptor-modified nk92 cell therapy in mouse models of human renal cell carcinoma.
Takaichi Y et al. J Neuropathol Exp Neurol 2018; (Epub) Deposition of Phosphorylated α-Synuclein in the rTg4510 Mouse Model of Tauopathy.
Snuderl M et al. Nat Commun 2018; 9 (1):2868 Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Kretschmer J et al. RNA 2018; (Epub) The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5'-3' exoribonuclease XRN1.
Daniels LJ et al. Cardiovasc Diabetol 2018; 17 (1):89 Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats.
Chung YH et al. Lab Invest 2018; (Epub) BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling.
Zhang N et al. J Cancer Sci Ther 2018; 10 (3) Separase Inhibitor Sepin-1 Inhibits Foxm1 Expression and Breast Cancer Cell Growth.
Hayashi K et al. Sci Signal 2018; 11 (528) the interaction between ikkα and lc3 promotes type i * production through the tlr9-containing laposome.
Lee CH et al. Mol Cell 2018; 70 (3):435-448.e5 Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
Mrazkova B et al. Aging (Albany NY) 2018; 10 (3):434-462 Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.
Tanabe Y et al. Oncotarget 2018; 9 (18):14428-14443 IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.
Stefanovic-Barrett S et al. EMBO Rep 2018; (Epub) MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.
Macdougall CE et al. Cell Metab 2018; 27 (3):588-601.e4 Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets.
Gomez-Virgilio L et al. Mol Neurobiol 2018; (Epub) Soluble Factors from Human Olfactory Neural Stem/Progenitor Cells Influence the Fate Decisions of Hippocampal Neural Precursor Cells.
Juneja M et al. J Neurol Neurosurg Psychiatry 2018; (Epub) PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.
Lan B et al. Am J Physiol Lung Cell Mol Physiol 2018; (Epub) Transient stretch induces cytoskeletal fluidization through the severing action of cofilin.
Coppe A et al. Hum Mutat 2018; (Epub) Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in Juvenile myelomonocytic leukemia patients.
Schultz CR et al. Biochem J 2018; (Epub) Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Nguyen G et al. Biochem Biophys Res Commun 2018; 495 (4):2649-2656 * ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and gpr91 inhibition.
Lee CH et al. bioRxiv 2017; (Epub) Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin.
Lee CH et al. bioRxiv 2017; (Epub) Distinct stimulatory mechanisms regulate the catalytic activity of Polycomb Repressive Complex 2 (PRC2).
Huang WY et al. J Dermatol Sci 2017; (Epub) Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction.
Chang WT et al. Molecules 2017; 22 (5) A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.
Hammoudi N et al. Cardiovasc Drugs Ther 2017; 31 (3):233-246 Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes.
Thompson EL et al. Nucleic Acids Res 2017; 45 (20):11837-11857 FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.
Gimpel P et al. Curr Biol 2017; 27 (19):2999-3009.e9 Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.
Lee YH et al. Oncol Lett 2017; 14 (1):171-179 DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells.
Damiani E et al. Sci Rep 2017; 7:41959 Platelet activating factor-induced expression of p21 is correlated with histone acetylation.
Hammerling BC et al. Nat Commun 2017; 8:14050 A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance.
Zhang C et al. Mol Oncol 2017; 11 (3):280-294 TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.
Bressan RB et al. Development 2017; 144 (4):635-648 Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.
Lin YY et al. Mar Drugs 2017; 15 (1) Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis.
Yang PY et al. Oncotarget 2017; 8 (3):4196-4207 Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation.
Shentu TP et al. Sci Rep 2017; 7 (1):18052 Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation.
Yamamoto W et al. J Cell Sci 2017; (Epub) Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P2 during yeast receptor-mediated endocytosis.
Kaehler M et al. Oncotarget 2017; 8 (54):92018-92031 MicroRNA-212/ABCG2-axis contributes to development of imatinib-resistance in leukemic cells.
Newman EA et al. Cell Death Dis 2017; 8 (12):3208 Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.
Su WC et al. J Virol 2017; (Epub) Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein is Crucial for Production of Infectious Virus Particles.
Li F et al. Diabetologia 2017; (Epub) loss of renal snx5 results in impaired ide activity and * resistance in mice.
Larhammar M et al. J Neurosci 2017; (Epub) The Ste20 family kinases MAP4K4, MINK1 and TNIK, converge to regulate stress induced JNK signaling in neurons.
Brifault C et al. J Biol Chem 2017; (Epub) Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuro-inflammation.
De Gasperi R et al. Sci Rep 2017; 7 (1):12888 Denervation-related alterations and biological activity of miRNAs contained in exosomes released by skeletal muscle fibers.
Garza-Contreras J et al. eNeuro 2017; 4 (4) Presence of Androgen Receptor Variant in Neuronal Lipid Rafts.
Rong X et al. J Clin Invest 2017; (Epub) ER phospholipid composition modulates lipogenesis during feeding and in obesity.
Tang B et al. Int J Cancer 2017; (Epub) microrna-324-5p regulates stemness, pathogenesis and sensitivity to * in multiple myeloma cells by targeting hedgehog signaling.
Chung YH et al. Int J Mol Sci 2017; 18 (8) MiR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition and Upregulates Expression of Tight Junction Protein Claudin-5 in Human Upper Tract Urothelial Carcinoma Cells.
King HA et al. Sci Rep 2017; 7 (1):6542 Generation of ribosome imprinted polymers for sensitive detection of translational responses.
Bouhy D et al. Acta Neuropathol 2017; (Epub) A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Bartova M et al. Clin Exp Metastasis 2017; Expression of ezrin and moesin in primary breast carcinoma and matched lymph node metastases.
Joly P et al. PLoS One 2017; 12 (6):e0179369 ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency.
Hammerling BC et al. Small GTPases 2017;:0 Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin.
Wang VY et al. Mol Cell 2017; Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.
Preusner M et al. Mol Cell 2017; Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals.
Lee KH et al. Sci Rep 2017; 7 (1):4787 Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway.
Pillay S et al. J Virol 2017; AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR.
Fang F et al. Sci Rep 2017; 7 (1):3868 Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease.
Park JW et al. Mod Pathol 2017; (Epub) FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate.
Zeng L et al. Biochem Pharmacol 2017; (Epub) MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation.
Xiao X et al. Nucleic Acids Res 2017; (Epub) Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Wu JH et al. J Eur Acad Dermatol Venereol 2017; (Epub) Dysregulation of the MEK/ERK/MNK1 signaling cascade by middle T antigen of the trichoydsplasia spinulosa polyomavirus.
Scherer SL et al. J Biol Chem 2017; (Epub) Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.
Zhang J et al. J Biol Chem 2017; (Epub) Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.
Guichard J et al. Am J Physiol Heart Circ Physiol 2017;:ajpheart.00027.2017 Desmin Loss and Mitochondrial Damage Precede Left Ventricular Systolic Failure in Volume Overload Heart Failure.
Dart AE et al. Oncogene 2017; (Epub) The drebrin/EB3 pathway drives invasive activity in prostate cancer.
Fujiki K et al. J Biol Chem 2017; (Epub) Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure.
Respondek D et al. PLoS One 2017; 12 (3):e0173259 PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection.
Chen Y et al. Cell Signal 2017; 33:107-121 Casein Kinase 2 Interacting Protein-1 regulates * and M2 inflammatory macrophage polarization.
Delaney JR et al. Nat Commun 2017; 8:14423 Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Wang T et al. Cell 2017; (Epub) Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.
Baba Y et al. Int J Mol Sci 2017; 18 (2) Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma.
Frasca D et al. Mech Ageing Dev 2017; (Epub) Obesity induces pro-inflammatory B cells and impairs B cell function in old mice.
Hutt DM et al. Methods Mol Biol 2017; 1510:77-91 Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation.
Korinek M et al. Phytomedicine 2016; 23 (14):1706-1715 Anti-allergic potential of Typhonium blumei: Inhibition of degranulation via suppression of PI3K/PLCγ2 phosphorylation and calcium influx.
Zhou W et al. Int J Mol Med 2016; 38:1481-1489 Expression of glycine receptors and gephyrin in rat medial vestibular nuclei and flocculi following unilateral labyrinthectomy.
Delphine B. et al. JND 2016; Preprint:43118 Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.
Lisa J. Bain et al. Toxicol Rep 2016; 3:405-413 Arsenic inhibits stem cell differentiation by altering the interplay between the Wnt3a and Notch signaling pathways.
Zhou W et al. Int J Mol Med 2016; 38 (5):1481-1489 Expression of glycine receptors and gephyrin in rat medial vestibular nuclei and flocculi following unilateral labyrinthectomy.
Gan Z et al. Cell Syst 2016; 3 (3):252-263.e8 Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration.
Zhang D et al. Oncotarget 2016; 7 (43):69149-69158 Targeting the ERK pathway for the treatment of Cushing's disease.
Ahmad F et al. Sci Rep 2016; 6:28056 Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.
Xiao X et al. Nat Commun 2016; 7:12193 Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Jiang P et al. Oncotarget 2016; 7 (36):57932-57942 Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells.
Starokadomskyy P et al. Nat Immunol 2016; 17 (5):495-504 dna polymerase-α regulates the activation of type i *s through cytosolic rna:dna synthesis.
Paudyal A et al. J Physiol 2016; 594 (12):3287-305 Nuclear accumulation of myocyte muscle LIM protein is regulated by heme oxygenase 1 and correlates with cardiac function in the transition to failure.
Chang WT et al. Anticancer Agents Med Chem 2016; (Epub) 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis.
Schultz AS et al. Mol Cell Biol 2016; (Epub) Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Yang HH et al. Proteomics Clin Appl 2016; (Epub) the putative involvement of actin binding proteins and cytoskeleton proteins in pathological mechanisms of * cystitis - revealed by a prospective pilot study using proteomic approaches.
Chroma K et al. Oncogene 2016; (Epub) Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.
Martinez-Castillo M et al. PLoS One 2016; 11 (11):e0165971 A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe.
Edmonds S et al. ACS Nano 2016; (Epub) Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines.
Sheets JN et al. Oncogenesis 2016; 5 (10):e264 SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance.
Kuga T et al. Sci Rep 2016; 6:34472 Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON.
Wu JH et al. J Med Virol 2016; Molecular mechanisms supporting a pathogenic role for human polyomavirus 6 small T antigen: Protein phosphatase 2A targeting and MAPK cascade activation.
Aryal B et al. Nat Commun 2016; 7:12313 ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Tsai WT et al. J Biol Chem 2016; 291 (37):19299-311 Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy.
Steven S et al. Br J Pharmacol 2016;
Wilhelmi I et al. Nat Commun 2016; 7:12347 Sec16 alternative splicing dynamically controls COPII transport efficiency.
Smith TH et al. J Biol Chem 2016; (Epub) Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of β-arrestins.
Hahm ER et al. Cell Cycle 2016;:43112 c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells.
Tsai KW et al. Sci Rep 2016; 6:28176 Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer.
Yu T et al. Cell Death Dis 2016; 7 (6):e2255 KLF4 deletion alters gastric cell lineage and induces MUC2 expression.
Mankouri J et al. J Virol 2016; (Epub) Release of infectious hepatitis C virus from Huh7 cells occurs via a trans-Golgi network to endosome pathway independent of VLDL.
Kuga T et al. Sci Rep 2016; 6:26557 FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes.
Toste PA et al. Mol Cancer Res 2016; 14 (5):437-47 Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK.
Pacold ME et al. Nat Chem Biol 2016; 12 (6):452-8 A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Li YH et al. J Biol Chem 2016; 291 (19):10277-92 Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.
Moreno-Lorenzana D et al. Cell Cycle 2016; (Epub):0 CDKIs p18INK4c and p57Kip2 are involved in quiescence of CML leukemic stem cells after treatment with TKI.
Rowe ER et al. J Biol Chem 2016; 291 (13):6664-78 Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1-3.
Pillay S et al. Nature 2016; ([Epub ahead of print]) An essential receptor for adeno-associated virus infection.
Wei-Chou Lin et al. Am J Cancer Res 2015; 5 (11):3350-3362 mln4924, a novel nedd8-activating enzyme inhibitor, exhibits antitumor activity and enhances *-induced cytotoxicity in human cervical carcinoma: in vitro and in vivo study.
Egerman MA et al. Cell Metab 2015; 22 (1):164-74 GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Ma F et al. J Immunol 2015; 194 (4):1545-54 Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.
Tian H et al. Mol Cancer Res 2015; 13 (4):784-94 Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Kelley RA et al. J Biol Chem 2015; 290 (8):5041-52 Retbindin is an extracellular riboflavin-binding protein found at the photoreceptor/retinal pigment epithelium interface.
Zhang X et al. Clin Cancer Res 2015; 21 (20):4698-708 SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer.
Huang TT et al. Oncotarget 2015; 6 (20):18012-26 The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis.
Zengel J et al. J Virol 2015; 89 (14):7338-47 Roles of Phosphorylation of the Nucleocapsid Protein of Mumps Virus in Regulating Viral RNA Transcription and Replication.
Jo A et al. Biomed Res Int 2015; 2015:305716 Efficient Mitochondrial Genome Editing by CRISPR/Cas9.
Grimsey NJ et al. J Cell Biol 2015; 210 (7):1117-31 Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.
Lin TB et al. J Neurosci 2015; 35 (50):16545-60 Fbxo3-Dependent Fbxl2 Ubiquitination Mediates Neuropathic Allodynia through the TRAF2/TNIK/GluR1 Cascade.
Wu JC et al. Sci Rep 2015; 5:18476 Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration.
Shi J et al. Mol Cell Biol 2015; 35 (19):512011 Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling.
Kohl S et al. Nat Genet 2015; 47 (7):757-65 Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
Paret C et al. Oncotarget 2015; 6 (28):25356-67 CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer.
Jacinto FV et al. Genes Dev 2015; 29 (12):1224-38 The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing.
Huber RM et al. Oncotarget 2015; 6 (4):2134-47 DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.
Chou CK et al. Int J Mol Sci 2015; 16 (7):15104-17 BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.
Kubli DA et al. PLoS One 2015; 10 (6):e0130707 PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes.
Virts EL et al. Hum Mol Genet 2015; 24 (18):5093-108 AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.
Fu H et al. Nat Commun 2015; 6:6746 The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage.
Yu HW et al. J Cell Mol Med 2015; 19 (5):934-47 β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration.
Yang M et al. J Lipid Res 2014; 55 (2):226-38 Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake.
Corradini E et al. Mol Cell Proteomics 2014; 13 (8):2004-16 Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.
Fragkouli A et al. Front Cell Neurosci 2014; 8:182 miR-7 and miR-153 protect neurons against MPP(+)-induced cell death via upregulation of mTOR pathway.
Jullienne A et al. J Cereb Blood Flow Metab 2014; 34 (10):1637-45 Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.
Hutt DM et al. PLoS One 2014; 9 (8):e106224 The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition.
Yang SH et al. Biomed Res Int 2014; 2014:312847 Andrographolide induces apoptosis of C6 glioma cells via the ERK-p53-caspase 7-PARP pathway.
Ma F et al. Nat Commun 2014; 5:5494 retinoid x receptor α attenuates host antiviral response by suppressing type i *.
Chaudhury I et al. Mol Cell Biol 2014; 34 (21):3939-54 FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.
Yeo JE et al. Hum Mol Genet 2014; 23 (14):3695-705 CtIP mediates replication fork recovery in a FANCD2-regulated manner.
Huang IH et al. J Cell Sci. 2014; 127 (Pt 19):4186-200 GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment.
Kang CC et al. Anal Chem 2014; 86 (20):10429-36 Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response.
Dvoriantchikova G et al. Eur J Neurosci 2014; Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways.
Lin CH et al. Int Immunopharmacol 2014; The effect of sesamin on airway fibrosis in vitro and in vivo.
James AW et al. Tissue Eng Part A 2014; Lentiviral delivery of PPARγ shRNA Alters the Balance of Osteogenesis and Adipogenesis, Improving Bone Microarchitecture.
Kohsaka S et al. Nat Genet 2014; 46 (6):595-600 A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.
Grabiner BC et al. Cancer Discov 2014; A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity.
Johnson MA et al. PLoS One 2014; 9 (4):e93597 Amino Acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis.
Colbert LE et al. Cancer Res 2014; CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer.
Al-Sawaf O et al. Sci Rep 2014; 4:3625 Nrf2 protects against TWEAK-mediated skeletal muscle wasting.
Morcavallo A et al. Matrix Biol 2014; decorin differentially modulates the activity of * receptor isoform a ligands.
Liu SH et al. Biochem Pharmacol 2014; 87 (2):229-42 Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy.
Lin W et al. EMBO J 2013; 32 (10):1425-39 Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity.
Ruisu K et al. PLoS One 2013; 8 (8):e74031 Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.
Chang YC et al. EMBO Mol Med 2013; 5 (8):1165-79 Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human.
Lam T et al. PLoS One 2013; 8 (11):e80414 Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
Zhang K et al. J Neurosci 2013; 33 (17):7451-62 Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling.
Son J et al. Genes Dev 2013; 27 (24):2663-77 Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Angulo-Rojo C et al. ASN Neuro 2013; 5 (5):e00130 Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA.
Hall WA et al. Oncogene 2013; Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
Krieger M et al. Brain 2013; 136 (Pt 12):3634-44 SIL1 mutations and clinical spectrum in patients with Marinesco-Sjogren syndrome.
Cho YW et al. PLoS One 2013; 8 (6):e66514 Zfp423 binds autoregulatory sites in p19 cell culture model.
Chaudhury I et al. Nucleic Acids Res 2013; 41 (13):6444-59 FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery.
Bennett BJ et al. Cell Metab 2013; 17 (1):49-60 Trimethylamine-N-oxide, a * associated with atherosclerosis, exhibits complex genetic and dietary regulation.
Yang Y et al. Nucleic Acids Res 2013; 41 (4):2296-312 Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage.
Sun Y et al. J Biol Chem 2012; 287 (48):40652-60 Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.
Lim ST et al. J Cell Biol 2012; 197 (7):907-19 Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
SDS
Thimerosal.pdf
产品包装 报价 (¥)
¥ 4000
¥ 1700
联系经销商
欣博盛生物科技有限公司
欣博盛生物科技有限公司
(全国热线) 4006-800-892 / (深圳) 0755-26755892 / (北京) 010-88594029 / (上海) 021-34613729 / (广州) 18024516375 / (香港) +852-69410778
http://www.neobioscience.com
genetex@neobioscience.com