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Glutamine synthetase抗体 [MSVA-750M] HistoMAX™

Comparison Orthogonal HistoMAX
Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471
Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471
Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471

目录号 GTX04471

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 MSVA-750M

同种型

 IgG2c

实验应用

 IHC-P

种属反应

 Human
产品包装
500 μl (¥8900),
100 μl (¥4200)
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产品说明

摘要

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

42 kDa. ( Note )

阳性对照

Liver: A strong GS staining should be seen of centrilobular hepatocytes while staining is weak to moderate in Kupffer cells.

Negative Control

Liver: Periportal hepatocytes must be GS negative in the normal liver.

产品属性

形式

Liquid

存储溶液

PBS, 0.05% BSA (Please contact us for PBS only format)

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant fragment (around aa 50-250) of human GLUL protein

纯化方式

Protein A/G purified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

glutamate-ammonia ligase , GLNS , GS , PIG43 , PIG59

细胞定位

Cytoplasm, cytosol , Microsome , Mitochondrion , Cell membrane

功能与背景

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

数据库

研究领域

產品图片

Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471

GTX04471 IHC-P Image

IHC-P analysis of human liver tissue section using GTX04471 Glutamine synthetase antibody [MSVA-750M] HistoMAX™.
Glutamine Synthetase staining is strong in centrilobular hepatocytes weak to moderate in Kupffer cells but absent in periportal hepatocytes.

Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471

GTX04471 IHC-P Image

IHC-P analysis of human hepatocellular carcinoma tissue section using GTX04471 Glutamine synthetase antibody [MSVA-750M] HistoMAX™.
Hepatocellular carcinoma with excessive Glutamine Synthetase positivity of all tumor cells.

Anti-Glutamine synthetase antibody [MSVA-750M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04471

GTX04471 IHC-P Image

IHC-P analysis of human skin squamous epithelium tissue section using GTX04471 Glutamine synthetase antibody [MSVA-750M] HistoMAX™.
In the skin, a nuclear and cytoplasmic Glutamine Synthetase staining can be seen in the lower third and in the top layers of the squamous epithelium.

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产品包装 报价 (¥)
¥ 8900
¥ 4200
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