产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| 1:50 - 1:200 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
Batch dependent (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
A synthesized peptide derived from hmuan HDAC1
纯化方式
Purified by affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
histone deacetylase 1 , GON-10 , HD1 , KDAC1 , RPD3 , RPD3L1
细胞定位
Nucleus
功能与背景
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
数据库
研究领域
產品图片
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/templates/default/js/lightbox/images/loading.gif "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
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GTX08970 WB Image
Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with HDAC1 antibody [GT1163] (GTX08970) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
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GTX08970 WB Image
WB analysis of various samples using GTX08970 HDAC1 antibody [GT1163].
Dilution : 1:1000
Loading : 25μg
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GTX08970 WB Image
WB analysis of Wild-type (WT) and HDAC1 knockout (KO) 293T cell extracts using GTX08970 HDAC1 antibody [GT1163].
Dilution : 1:1000
Loading : 25μg
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GTX08970 ICC/IF Image
ICC/IF analysis of C6 cells using GTX08970 HDAC1 antibody [GT1163].
Orange: Primary antibody
Blue: DAPI
Dlution : 1:100
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GTX08970 ICC/IF Image
ICC/IF analysis of NIH3T3 cells using GTX08970 HDAC1 antibody [GT1163].
Orange: Primary antibody
Blue: DAPI
Dlution : 1:100
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GTX08970 IHC-P Image
IHC-P analysis of rat testis tissue section using GTX08970 HDAC1 antibody [GT1163].
Dlution : 1:100
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GTX08970 IHC-P Image
IHC-P analysis of mouse brain tissue section using GTX08970 HDAC1 antibody [GT1163].
Dlution : 1:100
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文献引用
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产品评论
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![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_40000000050_20200306_WB_watermark_TPM_w_23053123_671.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20200327_WB_1_w_23053123_389.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20200327_WB_2_w_23053123_134.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20191101_AP_003_84_w_23053123_644.webp "Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20191101_AP_003_85_w_23053123_522.webp "Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20191101_AP_002_86_w_23053123_953.webp "Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970](/upload/website/prouct_img/small/GTX08970/GTX08970_20191101_AP_002_87_w_23053123_920.webp "Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_40000000050_20200306_WB_watermark_TPM_w_23053123_671.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20200327_WB_1_w_23053123_389.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20200327_WB_2_w_23053123_134.webp "Anti-HDAC1 antibody [GT1163] used in Western Blot (WB). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20191101_AP_003_84_w_23053123_644.webp "Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20191101_AP_003_85_w_23053123_522.webp "Anti-HDAC1 antibody [GT1163] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20191101_AP_002_86_w_23053123_953.webp "Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970")
![Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970](/upload/website/prouct_img/normal/GTX08970/GTX08970_20191101_AP_002_87_w_23053123_920.webp "Anti-HDAC1 antibody [GT1163] used in IHC (Paraffin sections) (IHC-P). GTX08970")
