产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预测种属反应
Mouse, Rat, Zebrafish, Chicken, Xenopus tropicalis(>80% identity)
产品属性
形式
Liquid
存储溶液
PBS, 2% BSA
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
batch dependent
免疫原种属
Human
免疫原
Recombinant fragment of human HMGA2
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
high mobility group AT-hook 2 ,BABL ,HMGI-C ,HMGIC ,LIPO ,STQTL9
细胞定位
Nucleus
功能与背景
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
数据库
研究领域
產品图片
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GTX639938 IHC-P Image
IHC-P analysis of human thyroid tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Follicular carcinoma with strong HMGA2 staining of all tumor cells.
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GTX639938 IHC-P Image
IHC-P analysis of human uterus endocervix tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Strong nuclear HMGA2 staining of epithelial cells.
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GTX639938 IHC-P Image
IHC-P analysis of human bronchus mucosa tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Strong nuclear HMGA2 staining of most respiratory epithelial cells.
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文献引用
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产品评论
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