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Her2 / ErbB2抗体 [MSVA-340R] HistoMAX™

HistoMAX
Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428
Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428
Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428

目录号 GTX04428

宿主

 Rabbit

克隆

 Monoclonal

克隆编号

 MSVA-340R

同种型

 IgG

实验应用

 IHC-P

种属反应

 Human
产品包装
500 μl (¥10800),
100 μl (¥4200)
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产品说明

摘要

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
IHC-P 1:50-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

138 kDa. ( Note )

阳性对照

Colon: Breast cancers with HER2 amplification should show strong positivity. Placenta: A faint staining should be seen at the surface membrane of the syncytiotrophoblast.

Negative Control

Breast: Normal epithelial cells must not show HER2 immunostaining.

产品属性

形式

Liquid

存储溶液

PBS, 0.05% BSA (Please contact us for PBS only format)

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encoding the extracellular domain of human c-erbB2

纯化方式

Protein A/G purified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

erb-b2 receptor tyrosine kinase 2 , CD340 , HER-2 , HER-2/neu , HER2 , MLN 19 , NEU , NGL , TKR1

细胞定位

Cell membrane , Cytoplasm, perinuclear region , Nucleus , Cytoplasm

功能与背景

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]

数据库

研究领域

產品图片

Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428

GTX04428 IHC-P Image

IHC-P analysis of human breast cancer tissue section using GTX04428 Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™.
Breast cancer of no special type NST HER2.

Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428

GTX04428 IHC-P Image

IHC-P analysis of human breast cancer tissue section using GTX04428 Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™.
Breast cancer of no special type NST HER2.

Anti-Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04428

GTX04428 IHC-P Image

IHC-P analysis of human Breast tissue section using GTX04428 Her2 / ErbB2 antibody [MSVA-340R] HistoMAX™.
Her2 / ErbB2 staining is lacking in normal breast in case of appropriate formalin fixation.

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产品包装 报价 (¥)
¥ 10800
¥ 4200
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