形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Carrier-protein conjugated synthetic peptide surrounding phospho Ser139 of human Histone H2A.X. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
RRID
AB_2910054
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
,H2A histone family member X,gamma H2A.X,gamma H2AX,H2A.X,H2A/X,H2AX,H2AFX,
细胞定位
Nucleus
功能与背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
数据库
研究领域
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in IHC (Paraffin sections) (IHC-P). GTX636713](/upload/website/prouct_img/small/GTX636713/GTX636713_44620_20220408_IHC-P_M_22071401_185.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in IHC (Paraffin sections) (IHC-P). GTX636713")
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Western Blot (WB). GTX636713](/upload/website/prouct_img/small/GTX636713/GTX636713_44620_20220318_WB_treatment_Cisplatin_w_23061202_205.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Western Blot (WB). GTX636713")
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636713](/upload/website/prouct_img/small/GTX636713/GTX636713_44620_20220429_ICC_IF_treatment_Cisplatin_w_23061202_303.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636713")
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in IHC (Paraffin sections) (IHC-P). GTX636713](/upload/website/prouct_img/normal/GTX636713/GTX636713_44620_20220408_IHC-P_M_22071401_185.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in IHC (Paraffin sections) (IHC-P). GTX636713")
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Western Blot (WB). GTX636713](/upload/website/prouct_img/normal/GTX636713/GTX636713_44620_20220318_WB_treatment_Cisplatin_w_23061202_205.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Western Blot (WB). GTX636713")
![Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636713](/upload/website/prouct_img/normal/GTX636713/GTX636713_44620_20220429_ICC_IF_treatment_Cisplatin_w_23061202_303.webp "Anti-Histone H2A.XS139ph (phospho Ser139) antibody [HL1299] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX636713")
