产品说明
摘要
C-reactive protein, also known as PTX1, is a member of the pentraxin family and is involved in complement activation and regulation. C-reactive proteins are found as non-covalently associated globular subunits of the serum-soluble cyclic pentameric complex. This recombinant human C- reactive protein corresponds to the 27.75 kDa (224 a.a.) isoform 1 with an intrachain disulfide bond and no glycosylation modification (RefSeq: NP_000558.2; UniProt ID: P02741). It is His-tagged at the C-terminus.
产品属性
形式
Lyophilized powder
存储溶液
Reconstitute with distilled water to 0.4 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.
保存剂
No Preservative
存放说明
Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.
Region/Sequence
C-terminal His tagged full-length Humans CRP protein (1-224aa of AAL48218.2)
表达系统
HEK293 cells
纯度
>95%
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
C-reactive protein , PTX1
细胞定位
Secreted
功能与背景
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
数据库
研究领域
產品图片
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GTX138453-pro Image
GTX138453-pro Human C Reactive Protein, His tag was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.
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GTX138453-pro ELISA Image
Indirect ELISA analysis was performed by coating the plate with recombinant Human C Reactive Protein, His tag (GTX138453-pro) (144.14-2.25 nM). Coated protein was probed with C Reactive Protein antibody [N1C3] (GTX101262) (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect the bound primary antibody.
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