产品应用
产品属性
形式
Lyophilized powder
存储溶液
Reconstitute with ddH₂O to a concentration less than 100 μg/ml. Lyophilized from a 0.2 μm filtered solution of PBS pH 7.4.
保存剂
No preservatives
存放说明
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Region/Sequence
C-terminal His tagged, mature human CD66e protein (P06731, aa Lys35-Ala685)
表达系统
Human cells
纯度
>95% by SDS-PAGE
内毒素
< 1 EU/弮g (Determined by LAL assay)
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
carcinoembryonic antigen related cell adhesion molecule 5 , CD66e , CEA
细胞定位
Cell membrane , Apical cell membrane , Cell surface
功能与背景
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
数据库
研究领域
文献引用
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产品评论
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