产品应用
产品属性
形式
Lyophilized powder
存储溶液
Reconstitute with distilled water to 0.9 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.
保存剂
No Preservative
存放说明
Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.
Region/Sequence
C-terminal His tagged full-length Human IL1B protein (1-269aa of NP_000567.1)
表达系统
HEK293 cells
纯度
>95%
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
细胞定位
Cytoplasm, cytosol,Lysosome,Secreted
功能与背景
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
数据库
研究领域
產品图片
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GTX138452-pro Image
GTX138452-pro Human IL1 beta, His tag was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.
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文献引用
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