产品应用
应用说明
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effects is less or equal to 1.5 ng/ml.
Observed MW
13.5-18 kDa.
Default 3
7.4
产品属性
形式
Liquid
存储溶液
PBS, 10% Glycerol
保存剂
No preservative
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
C-terminal His-Tag; Length: 124 a.a. Sequence: ADPIPTEIPT SALVKETLAL LSTHRTLLIA NETLRIPVPV HKNHQLCTEE IFQGIGTLES QTVQGGTVER LFKNLSLIKK YIDGQKKKCG
EERRRVNQFL DYLQEFLGVM NTEWIIESHH HHHH
表达系统
Baculovirus
纯度
> 90% by SDS-PAGE.
内毒素
< 1.0 EU/μg (determined by LAL method)
偶联
Unconjugated
注意事项
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
相关讯息
别名
interleukin 5 , EDF , IL-5 , TRF
功能与背景
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
数据库
研究领域
產品图片
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GTX67068-pro Image
3 μg of GTX67068-pro Human IL5 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
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文献引用
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产品评论
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