产品应用
产品属性
形式
Lyophilized powder
存储溶液
Reconstitute with distilled water to 1.5 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.
保存剂
No Preservative
存放说明
Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.
Region/Sequence
C-terminal His tagged Human IL5 protein (1-134 a.a. of NP_000870.1)
表达系统
HEK293 cells
纯度
>85%
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
interleukin 5 , EDF , IL-5 , TRF
细胞定位
Secreted
功能与背景
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
数据库
研究领域
產品图片
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GTX139317-pro Image
GTX139317-pro Human IL5 protein, His tag was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.
The predicted molecular weight determined by ESI-TOF is 13206.27 Da (+/- 10 Da by ESI-TOF). The observed MW is 13208.40 Da. Additional masses at 13411.42 Da and 13776.69 Da are observed due to residual O-glycans.
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文献引用
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产品评论
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