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Influenza A virus M1 (matrix protein)抗体

Anti-Influenza A virus M1 (matrix protein) antibody used in Western Blot (WB). GTX127356

目录号 GTX127356

文献引用 5

宿主

 Rabbit

克隆

 Polyclonal

同种型

 IgG

实验应用

 WB, ELISA

种属反应

 Influenza A virus
产品包装
100 μl (¥4000),
25 μl (¥1700)
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产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ELISA Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

28 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

PBS, 1% BSA, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.37 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Influenza A virus

免疫原

Recombinant protein encompassing a sequence within the Internal region of Influenza A virus M1 (matrix protein) (A/Puerto Rico/8/1934(H1N1). The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_2885647

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

Influenza A Virus Membrane 1 protein , Influenza A Virus M1

功能与背景

Influenza A virus matrix 1, M1, is a critical protein required for assembly and budding. Hemagglutinin associates with M1 via its cytoplasmic tail and transmembrane domain. The M2 and nucleoprotein proteins are critical in the replication cycle of influenza viruses. The M2 channel protein is an essential component of the viral envelope because of its ability to form a highly selective, pH-regulated, proton-conducting channel. The M2 channel allows protons to enter the interior of the virus and acidification weakens the interaction of the M1 protein with the ribonuclear core.

研究领域

產品图片

Anti-Influenza A virus M1 (matrix protein) antibody used in Western Blot (WB). GTX127356

GTX127356 WB Image

Non-infected (–) and infected (+) C6/36 whole cell extracts (15 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Influenza A virus M1 (matrix protein) antibody (GTX127356) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

文献引用

Application Reference

Han YJ et al. J Biomed Sci 2023; 30 (1) : 10 Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites.
Masami Shiimori et al. iScience 2021; 24 (6) : 102660 Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation.
实验应用 : WB
Russier M et al. J Virol 2020; 94 (3) Hemagglutinin Stability Regulates H1N1 Influenza Virus Replication and Pathogenicity in Mice by Modulating Type I Interferon Responses in Dendritic Cells.
Marion Russier et al. bioRxiv 2019; (Epub) HA stability regulates H1N1 influenza virus replication and pathogenicity in mice by modulating type I interferon responses in dendritic cells.
实验应用 : WB
Deo VK et al. Mol Pharm 2015; 12 (3) : 839-45 Chimeric virus-like particles made using GAG and * capsid proteins providing dual drug delivery and vaccination platform.
实验应用 : ELISA
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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
产品包装 报价 (¥)
¥ 4000
¥ 1700
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