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Integrin alpha 4抗体 [9F10] (PE)
目录号 GTX01494-08
目录号 GTX01494-08
![Anti-Integrin alpha 4 antibody [9F10] (PE) used in Flow cytometry (FCM). GTX01494-08](/upload/website/prouct_img/normal/GTX01494-08/GTX01494-08_20200428_FACS109_w_23053121_607.webp)
GTX01494-08 FCM Image
FACS analysis of human peripheral blood lymphocytes using GTX01494-08 Integrin alpha 4 antibody [9F10] (PE).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)
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![Anti-Integrin alpha 4 antibody [9F10] (PE) used in Flow cytometry (FCM). GTX01494-08](/upload/website/prouct_img/middle/GTX01494-08/GTX01494-08_20200428_FACS109_w_23053121_607.webp){kind=small}
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宿主Mouse
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克隆Monoclonal
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克隆编号9F10
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同种型IgG1
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实验应用FCM
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种属反应Human
摘要
The 9F10 monoclonal antibody reacts with human CD49d, a 150kD integral membrane protein that is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can also dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1. CD49d is involved in cellular adhesion to other cells as well as extracellular matrix.