产品说明
产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
实验应用 |
稀释倍数 |
1:100-1:200 |
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
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WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
Skin: A strong KLK7 staining should be seen in the stratum granulosum and possibly also in the keratinizing cell layers.
Negative Control
Colon: KLK7 immunostaining should be absent in all cells of the colon mucosa
产品属性
形式
Liquid
存储溶液
10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant human KLK7 protein
纯化方式
Protein A/G purified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
kallikrein related peptidase 7 , PRSS6 , SCCE , hK7
细胞定位
Secreted
功能与背景
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
数据库
研究领域
產品图片
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GTX04475 IHC-P Image
IHC-P analysis of human skin tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™. A strong Kallikrein 7 staining in the stratum granulosum and the keratinizing superficial layer of the skin.
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GTX04475 IHC-P Image
IHC-P analysis of human squamous cell carcinoma tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™. Squamous cell carcinoma showing strong Kallikrein 7 staining in areas of keratinization.
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GTX04475 IHC-P Image
IHC-P analysis of human colon mucosa tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™. Kallikrein 7 staining is absent in all cells of the colon mucosa.
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文献引用
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产品评论
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