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MMP3抗体 [N3C1], Internal

Orthogonal
Anti-MMP3 antibody [N3C1], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100723
Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723
Anti-MMP3 antibody [N3C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX100723
Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723
Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723

目录号 GTX100723

文献引用 7

宿主

 Rabbit

克隆

 Polyclonal

同种型

 IgG

实验应用

 WB, ICC/IF, IHC-P

种属反应

 Human
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 MMP3 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

54 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

0.1M Tris, 0.1M Glycine, 10% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MMP3. The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_1950933

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

matrix metallopeptidase 3 , CHDS6 , MMP-3 , SL-1 , STMY , STMY1 , STR1

细胞定位

Secreted , extracellular space , extracellular matrix

功能与背景

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

数据库

研究领域

產品图片

Anti-MMP3 antibody [N3C1], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100723

GTX100723 ICC/IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using MMP3(GTX100723) antibody at 1:200 dilution.

Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723

GTX100723 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with MMP3 antibody [N3C1], Internal (GTX100723) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-MMP3 antibody [N3C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX100723

GTX100723 IHC-P Image

Immunohistochemical analysis of paraffin-embedded A549 xenograft, using MMP3(GTX100723) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723

GTX100723 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with MMP3 antibody [N3C1], Internal (GTX100723) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-MMP3 antibody [N3C1], Internal used in Western Blot (WB). GTX100723

GTX100723 WB Image

Orthogonal

The data was published in the journal Nat Commun in 2017.PMID: 28489070

文献引用

Application Reference

Cheng TC et al. Acta Pharm Sin B 2021; 29 (4) : 622-637 Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.
实验应用 : WB
种属反应 : Human
Mandal JP et al. Free Radic Biol Med 2021; 163 : 69-87 PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression.
实验应用 : WB
种属反应 : Human
Huang HY et al. J Cell Mol Med 2020; Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis.
实验应用 : WB
种属反应 : Human
Wang C et al. Biotechnol Lett 2020; 42 (8) : 1567-1579 Mechanical injury and IL-1β regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes.
实验应用 : WB
种属反应 : Human
Li JM et al. Ther Adv Med Oncol 2018; 10 : 1.76E+15 Upregulation of LGALS1 is associated with oral cancer metastasis.
实验应用 : WB
种属反应 : Human
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Glycerol.pdf
Thimerosal.pdf
产品包装 报价 (¥)
¥ 4000
¥ 1700
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