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Melanoma gp100抗体 [PMEL/2037]

Anti-Melanoma gp100 antibody [PMEL/2037] used in IHC (Paraffin sections) (IHC-P). GTX17772
Anti-Melanoma gp100 antibody [PMEL/2037] used in Protein Array (Protein Array). GTX17772
Anti-Melanoma gp100 antibody [PMEL/2037] used in IHC (Paraffin sections) (IHC-P). GTX17772

目录号 GTX17772

宿主

Mouse

克隆

Monoclonal

克隆编号

PMEL/2037

同种型

IgG1

实验应用

IHC-P, ELISA, Protein Array

种属反应

Human
产品包装
100 μg (¥7000)

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
IHC-P 1-2μg/ml for 30 minutes at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).

WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

70 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

10mM PBS, 0.05% BSA

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

A recombinant fragment (around aa 376-502) of human SILV protein (exact sequence is proprietary)

纯化方式

Protein A/G purified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

D12S53E , ME20 , ME20M , P1 , P100 , PMEL , PMEL17 , SI , SIL , SILV , gp100 , premelanosome protein , Pmel 17

细胞定位

Endoplasmic reticulum membrane,Golgi apparatus,Melanosome,Endosome,Multivesicular body,Secreted

功能与背景

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

数据库

研究领域

產品图片

Anti-Melanoma gp100 antibody [PMEL/2037] used in IHC (Paraffin sections) (IHC-P). GTX17772

GTX17772 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX17772 Melanoma gp100 antibody [PMEL/2037].

Anti-Melanoma gp100 antibody [PMEL/2037] used in Protein Array (Protein Array). GTX17772

GTX17772 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using PMEL/gp100 Mouse Monoclonal Antibody (PMEL/2037). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-Melanoma gp100 antibody [PMEL/2037] used in IHC (Paraffin sections) (IHC-P). GTX17772

GTX17772 IHC-P Image

IHC-P analysis of human skin tissue using GTX17772 Melanoma gp100 antibody [PMEL/2037].

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SDS
PBS.pdf
Sodium Azide.pdf
产品包装 报价 (¥)
¥ 7000
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