形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Mouse
免疫原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse Myelin basic Protein. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein G.
偶联
Unconjugated
RRID
AB_2888434
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
myelin basic protein , C76307 , Hmbpr , R75289 , golli-mbp , jve , mld , shi
细胞定位
Isoform 13: Myelin membrane; Peripheral membrane protein; Cytoplasmic side , Isoform 12: Myelin membrane; Peripheral membrane protein; Cytoplasmic side , Isoform 11: Myelin membrane; Peripheral membrane protein; Cytoplasmic side , Isoform 10: Myelin membr
功能与背景
The protein encoded by the classic Mbp gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, Mbp-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long Mbp gene (otherwise called "Golli-Mbp") that contains 3 additional exons located upstream of the classic Mbp exons. Alternative splicing from the Golli and the Mbp transcription start sites gives rise to 2 sets of Mbp-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-Mbp, spliced in-frame to 1 or more Mbp exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to Mbp aa sequence. The second family of transcripts contain only Mbp exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the Mbp transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. Mutation of the Mbp gene is associated with the 'shiverer' and 'myelin deficient' phenotypes in mouse. [provided by RefSeq, Jul 2008]
数据库
研究领域
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292](/upload/website/prouct_img/small/GTX634292/GTX634292_42926_20231222_IHC-Fr_M_24021917_489.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in Western Blot (WB). GTX634292](/upload/website/prouct_img/small/GTX634292/GTX634292_42926_20170825_WB_M_brain_w_23061202_246.webp "Anti-Myelin basic protein antibody [GT3412] used in Western Blot (WB). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292](/upload/website/prouct_img/small/GTX634292/GTX634292_42926_20170807_IHC-Fr_M_w_23061202_566.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Paraffin sections) (IHC-P). GTX634292](/upload/website/prouct_img/small/GTX634292/GTX634292_42926_20170818_IHC-P_R_w_23061202_184.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Paraffin sections) (IHC-P). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292](/upload/website/prouct_img/normal/GTX634292/GTX634292_42926_20231222_IHC-Fr_M_24021917_489.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in Western Blot (WB). GTX634292](/upload/website/prouct_img/normal/GTX634292/GTX634292_42926_20170825_WB_M_brain_w_23061202_246.webp "Anti-Myelin basic protein antibody [GT3412] used in Western Blot (WB). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292](/upload/website/prouct_img/normal/GTX634292/GTX634292_42926_20170807_IHC-Fr_M_w_23061202_566.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Paraffin sections) (IHC-P). GTX634292](/upload/website/prouct_img/normal/GTX634292/GTX634292_42926_20170818_IHC-P_R_w_23061202_184.webp "Anti-Myelin basic protein antibody [GT3412] used in IHC (Paraffin sections) (IHC-P). GTX634292")
![Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292](/upload/website/support/rewardsprogram/normal/genetex_GTX634292_IHC-Fr_20210406_21040523_432.jpg "Anti-Myelin basic protein antibody [GT3412] used in IHC (Frozen sections) (IHC-Fr). GTX634292")
