形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
2 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the center region of human NFkB p105. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
nuclear factor kappa B subunit 1 , CVID12 , EBP-1 , KBF1 , NF-kB1 , NF-kappa-B1 , NF-kappaB , NFKB-p105 , NFKB-p50 , NFkappaB , p105 , p50
细胞定位
Nucleus,Cytoplasm
功能与背景
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Feb 2016]
数据库
研究领域
![Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436](/upload/website/prouct_img/small/GTX637436/GTX637436_T-44802_20221014_WB_KO_watermark_22101717_495.webp "Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436")
![Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436](/upload/website/prouct_img/small/GTX637436/GTX637436_T-44802_20220923_WB_TPM_watermark_22101717_780.webp "Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436")
![Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436](/upload/website/prouct_img/normal/GTX637436/GTX637436_T-44802_20221014_WB_KO_watermark_22101717_495.webp "Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436")
![Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436](/upload/website/prouct_img/normal/GTX637436/GTX637436_T-44802_20220923_WB_TPM_watermark_22101717_780.webp "Anti-NFkB p105 antibody [HL1784] used in Western Blot (WB). GTX637436")
