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PCSK9抗体 [HL2814]

Recombinant antibody KO/KD Orthogonal
Anti-PCSK9 antibody [HL2814] used in Western Blot (WB). GTX639955
Anti-PCSK9 antibody [HL2814] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639955

目录号 GTX639955

1

宿主

 Rabbit

克隆

 Monoclonal

克隆编号

 HL2814

同种型

 IgG

实验应用

 WB, ICC/IF

种属反应

 Human
产品包装
100 μl (¥4000),
25 μl (¥1700)
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产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:1000
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

74 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

PBS

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

batch dependent (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant fragment of human PCSK9.

纯化方式

Affinity purified by Protein A.

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

proprotein convertase subtilisin/kexin type 9 , FH3 , HCHOLA3 , LDLCQ1 , NARC-1 , NARC1 , PC9

细胞定位

Cytoplasm,Secreted,Endosome,Lysosome,Cell surface,Endoplasmic reticulum,Golgi apparatus

功能与背景

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

数据库

研究领域

產品图片

Anti-PCSK9 antibody [HL2814] used in Western Blot (WB). GTX639955

GTX639955 WB Image

Orthogonal

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PCSK9 antibody [HL2814] (GTX639955) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

Anti-PCSK9 antibody [HL2814] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639955

GTX639955 ICC/IF Image

PCSK9 antibody [HL2814] detects PCSK9 protein at Golgi apparatus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: PCSK9 stained by PCSK9 antibody [HL2814] (GTX639955) diluted at 1:500.
Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).

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产品评论

PCSK9 antibody [HL2814] 目录号 GTX639955

Rating
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实验应用
Western Blot(WB)
( Average 5 based on 1 users reviews)
Anti-PCSK9 antibody [HL2814] used in Western Blot (WB). GTX639955
Date : Anonymous submitted on 20-Mar-2024
Score :
Application Tested : WB
Sample Species : Hu
Sample : HeLa cells with/without PCSK9 KO treatment
Amount used : 30μg
Primary Antibody : 1:1000, 4°C, >12Hr
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产品包装 报价 (¥)
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¥ 1700
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