产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| 1:100-1:1000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Mouse
免疫原
Synthetic peptide of mouse PD-L1
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
CD274 antigen , A530045L16Rik , B7h1 , Pdcd1l1 , Pdcd1lg1 , Pdl1
细胞定位
Cell membrane,Early endosome membrane
功能与背景
The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]
数据库
研究领域
產品图片
![Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348](/templates/default/js/lightbox/images/loading.gif "Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348")
|
GTX638348 WB Image
Mouse tissue extract (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PD-L1 antibody [HL2293] (GTX638348) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
|
|
|
GTX638348 IHC-P Image
PD-L1 antibody [HL2293] detects PD-L1 protein at cell membrane and nucleus by immunohistochemical analysis.Sample: Paraffin-embedded mouse placenta.PD-L1 stained by PD-L1 antibody [HL2293] (GTX638348) diluted at 1:1000.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
|
文献引用
目前没有使用 PD-L1 antibody [HL2293] (GTX638348) 的文献被收录。快来回报我们第一篇参考文献吧！
产品评论
目前没有使用 PD-L1 antibody [HL2293] (GTX638348) 的产品评论被收录。快发表第一篇产品评论吧！
![Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348](/upload/website/prouct_img/small/GTX638348/GTX638348_45145_20230908_WB_M_thymus_23091319_904.webp "Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348")
![Anti-PD-L1 antibody [HL2293] used in IHC (Paraffin sections) (IHC-P). GTX638348](/upload/website/prouct_img/small/GTX638348/GTX638348_T-44984_20230714_IHC-P_M_23080901_176.webp "Anti-PD-L1 antibody [HL2293] used in IHC (Paraffin sections) (IHC-P). GTX638348")
![Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348](/upload/website/prouct_img/normal/GTX638348/GTX638348_45145_20230908_WB_M_thymus_23091319_904.webp "Anti-PD-L1 antibody [HL2293] used in Western Blot (WB). GTX638348")
![Anti-PD-L1 antibody [HL2293] used in IHC (Paraffin sections) (IHC-P). GTX638348](/upload/website/prouct_img/normal/GTX638348/GTX638348_T-44984_20230714_IHC-P_M_23080901_176.webp "Anti-PD-L1 antibody [HL2293] used in IHC (Paraffin sections) (IHC-P). GTX638348")
