GeneTex中国官方网站
  • China

PD-L1抗体 [MSVA-711R] HistoMAX™

HistoMAX
Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362
Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362
Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362

目录号 GTX04362

宿主

 Rabbit

克隆

 Monoclonal

克隆编号

 MSVA-711R

同种型

 IgG

实验应用

 IHC-P

种属反应

 Human
产品包装
500 μl (¥11100),
100 μl (¥4200)
查看所有 PD-L1 的产品
产品说明

摘要

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 9.0 Tris-EDTA-based Target Retrieval Solution buffer. Based on the testing result, the pH 9.0 showed a strongest staining pattern. The pH 7.8 is acceptable but lower pH results in a significant reduction of sensitivity.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48 and BOND RX - Leica. The detailed steps by Autostainer please refer to the protocol.
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

33 kDa. ( Note )

阳性对照

Alveolar macrophages, tonsil crypt epithelium and the placental cytotrophoblast show strong, predominantly membranous positivity. Follicle centre macrophages should show at least moderate intensity staining.

Negative Control

Appendix (negative staining of all epithelial cells)

产品属性

形式

Liquid

存储溶液

PBS, 0.05% BSA (Please contact us for PBS only format)

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

KLH-conjugated linear peptide corresponding to human PD-L1

纯化方式

Protein A/G purified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

CD274 molecule , B7-H , B7H1 , PD-L1 , PDCD1L1 , PDCD1LG1 , PDL1

细胞定位

Cell membrane , Early endosome membrane

功能与背景

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

数据库

研究领域

產品图片

Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362

GTX04362 IHC-P Image

IHC-P analysis of human placenta mature tissue section using GTX04362 PD-L1 antibody [MSVA-711R] HistoMAX™..

Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362

GTX04362 IHC-P Image

IHC-P analysis of human colorectal adenocarcinoma tissue section using GTX04362 PD-L1 antibody [MSVA-711R] HistoMAX™..

Anti-PD-L1 antibody [MSVA-711R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04362

GTX04362 IHC-P Image

IHC-P analysis of human breast cancer tissue section using GTX04362 PD-L1 antibody [MSVA-711R] HistoMAX™..
Breast cancer NST with PD L1 negative tumor cells but intense PD L1 staining in tumor associated inflammatory cells.

文献引用

目前没有使用 PD-L1 antibody [MSVA-711R] HistoMAX™ (GTX04362) 的文献被收录。快来回报我们第一篇参考文献吧！
我要回报文献

产品评论

目前没有使用 PD-L1 antibody [MSVA-711R] HistoMAX™ (GTX04362) 的产品评论被收录。快发表第一篇产品评论吧！
我要评论产品
产品包装 报价 (¥)
¥ 11100
¥ 4200
联系经销商
欣博盛生物科技有限公司
欣博盛生物科技有限公司
(全国热线) 4006-800-892 / (深圳) 0755-26755892 / (北京) 010-88594029 / (上海) 021-34613729 / (广州) 18024516375 / (香港) +852-69410778
http://www.neobioscience.com
genetex@neobioscience.com