产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:10000 |
| 1:100-1:500 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
human PMS2-transfected 293T cells , A431 , HeLa , HepG2
预测种属反应
Mouse, Bovine(>80% identity)
产品属性
形式
Liquid
存储溶液
PBS, 20% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the N-terminus region of human PMS2. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_2037723
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2
细胞定位
Nucleus
功能与背景
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
数据库
研究领域
產品图片
![Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804](/templates/default/js/lightbox/images/loading.gif "Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804")
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GTX113804 IP Image
Immunoprecipitation of PMS2 protein from HeLa whole cell extracts using 5 μg of PMS2 antibody [N1N3] (GTX113804).
Western blot analysis was performed using PMS2 antibody [N1N3] (GTX113804) diluted at 1:500.
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.
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GTX113804 WB Image
PMS2 antibody [N1N3] detects PMS2 protein by western blot analysis.
A. 30 μg A431 whole cell extract
B. 30 μg HeLa whole cell extract
C. 30 μg HepG2 whole cell extract
7.5 % SDS-PAGE
PMS2 antibody [N1N3] (GTX113804) dilution: 1:1000
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GTX113804 WB Image
PMS2 antibody [N1N3] detects PMS2 protein by western blot analysis.
A. 30 μg 293T whole cell extract
B. 30 μg whole cell extract of human PMS2-transfected 293T cells
7.5 % SDS-PAGE
PMS2 antibody [N1N3] (GTX113804) dilution: 1:5000
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文献引用
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产品评论
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![Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804](/upload/website/prouct_img/small/GTX113804/GTX113804_41577_IP_w_23060501_678.webp "Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804")
![Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804](/upload/website/prouct_img/small/GTX113804/GTX113804_41577_WB_w_23060501_517.webp "Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804")
![Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804](/upload/website/prouct_img/small/GTX113804/GTX113804_41577_WB_B_w_23060501_442.webp "Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804")
![Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804](/upload/website/prouct_img/normal/GTX113804/GTX113804_41577_IP_w_23060501_678.webp "Anti-PMS2 antibody [N1N3] used in Immunoprecipitation (IP). GTX113804")
![Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804](/upload/website/prouct_img/normal/GTX113804/GTX113804_41577_WB_w_23060501_517.webp "Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804")
![Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804](/upload/website/prouct_img/normal/GTX113804/GTX113804_41577_WB_B_w_23060501_442.webp "Anti-PMS2 antibody [N1N3] used in Western Blot (WB). GTX113804")
