形式
Liquid
存储溶液
1x TBS (pH7.4), 1% BSA, 40% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein
纯化方式
Protein A purified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
protein tyrosine phosphatase non-receptor type 11 , BPTP3 , CFC , JMML , METCDS , NS1 , PTP1D , PTP2C , PTPN11 , SHP2 , SHPTP2 , SHPTP3 , protein tyrosine phosphatase, nonreceptor type 11
细胞定位
Cytoplasm
功能与背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
数据库
研究领域
![Anti-SHP2 antibody [SD20-75] used in Western Blot (WB). GTX01144](/upload/website/prouct_img/small/GTX01144/GTX01144_HJ0727_20200228_WB_w_23053121_967.webp "Anti-SHP2 antibody [SD20-75] used in Western Blot (WB). GTX01144")
![Anti-SHP2 antibody [SD20-75] used in Western Blot (WB). GTX01144](/upload/website/prouct_img/normal/GTX01144/GTX01144_HJ0727_20200228_WB_w_23053121_967.webp "Anti-SHP2 antibody [SD20-75] used in Western Blot (WB). GTX01144")
