产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:1000-1:10000 |
| 1:100-1:1000 |
| 1:100-1:1000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
293T
预测种属反应
Bovine, Chicken, Xenopus tropicalis(>80% identity)
产品属性
形式
Liquid
存储溶液
PBS, 20% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
RRID
AB_2888400
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
TAR DNA binding protein , ALS10 , TDP-43
细胞定位
Nucleus
功能与背景
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
数据库
研究领域
產品图片
![Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973](/templates/default/js/lightbox/images/loading.gif "Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973")
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GTX633973 WB Image
Whole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT6310] (GTX633973) diluted at 1:5000.
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GTX633973 IHC-Fr Image
TDP43 antibody [GT6310] detects TDP43 Protein expression by immunohistochemical analysis.
Sample: Frozen-sectioned adult mouse cerebellum.
Green: TDP43 stained by TDP43 antibody [GT6310] (GTX633973) diluted at 1:250.
Red: Calbindin, stained by Calbindin antibody (GTX130856) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 5 min
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GTX633973 IHC-P Image
TDP43 antibody [GT6310] detects TDP43 protein at nucleus in mouse brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse brain.
TDP43 antibody [GT6310] (GTX633973) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX633973 IHC-P Image
TDP43 antibody [GT6310] detects TDP43 protein at nucleus in mouse lung by immunohistochemical analysis.
Sample: Paraffin-embedded mouse lung.
TDP43 antibody [GT6310] (GTX633973) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX633973 IHC-P Image
TDP43 antibody [GT6310] detects TDP43 protein at nucleus in rat brain by immunohistochemical analysis.
Sample: Paraffin-embedded rat brain.
TDP43 antibody [GT6310] (GTX633973) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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文献引用
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产品评论
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![Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973](/upload/website/prouct_img/small/GTX633973/GTX633973_42730_20170119_WB_w_23061202_332.webp "Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Frozen sections) (IHC-Fr). GTX633973](/upload/website/prouct_img/small/GTX633973/GTX633973_42730_20170829_IHC-Fr_M_w_23061202_828.webp "Anti-TDP43 antibody [GT6310] used in IHC (Frozen sections) (IHC-Fr). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/small/GTX633973/GTX633973_42730_20170329_IHC-P_M_1_w_23061202_997.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/small/GTX633973/GTX633973_42730_20170425_IHC-P_M_2_w_23061202_679.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/small/GTX633973/GTX633973_42730_20170329_IHC-P_R_w_23061202_752.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
![Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973](/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170119_WB_w_23061202_332.webp "Anti-TDP43 antibody [GT6310] used in Western Blot (WB). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Frozen sections) (IHC-Fr). GTX633973](/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170829_IHC-Fr_M_w_23061202_828.webp "Anti-TDP43 antibody [GT6310] used in IHC (Frozen sections) (IHC-Fr). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170329_IHC-P_M_1_w_23061202_997.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170425_IHC-P_M_2_w_23061202_679.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
![Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973](/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170329_IHC-P_R_w_23061202_752.webp "Anti-TDP43 antibody [GT6310] used in IHC (Paraffin sections) (IHC-P). GTX633973")
