产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 0.5 - 2 μg/ml |
| 1:100 - 1:1000 |
| 1:250 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
Tris-Glycine, 150mM NaCl
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
A synthetic peptide to a C-terminal region [within residues 350-414] of the human TARDBP protein. [Swiss-Prot# Q13148]
纯化方式
Purified by antigen-affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
TAR DNA binding protein , ALS10 , TDP-43
细胞定位
Nucleus,Cytoplasm
功能与背景
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
数据库
研究领域
產品图片
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GTX48590 ICC/IF Image
ICC/IF analysis of MCF-7 cells using GTX48590 TDP43 antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI
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GTX48590 WB Image
WB analysis of HeLa cell lysate using GTX48590 TDP43 antibody.
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GTX48590 IHC-P Image
IHC-P analysis of human placenta tissue using GTX48590 TDP43 antibody.
Dilution : 1:250
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)
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GTX48590 ICC/IF Image
ICC/IF analysis of human iPS derived neuron cells using GTX48590 TDP43 antibody.
Red : primary antibody
Blue : DAPI
Dilution : 1:200
Permibilization : 0.3% Triton X-100
Fixation : 4% PFA
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GTX48590 WB Image
WB analysis of cell ovreexpresing TDP43 lysate using GTX48590 TDP43 antibody.
Loading : 5μg
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