产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| Assay dependent |
| Assay dependent |
|
Note :
Sandwich ELISA
Capture: GTX03004, Detection: GTX03003-02.
|
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品说明
This antibody is able to detect native and recombinant human latent Transforming Growth Factor-β1 (TGF-β1), binds to the Latency Associated Protein (LAP), which is a part of the latent TGF-β1 complex and does not bind to latent TGF-β2 or -β3.
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant latent TGF-β1
纯化方式
Protein G purified
From tissue culture supernatant
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
CED,DPD1,LAP,TGFB,TGFB1,TGFbeta,transforming growth factor beta 1,TGF beta 1
细胞定位
Secreted,Extracellular space,Extracellular matrix
功能与背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
数据库
研究领域
產品图片
![Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004](/templates/default/js/lightbox/images/loading.gif "Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004")
|
GTX03004 ELISA Image
Sandwich ELISA analysis of human Latent TGF- beta1 protein using GTX03004 TGF beta 1 antibody [MT593] as coating antibody and GTX03003-02 TGF beta 1 antibody [MT517] (Biotin) as detecting antibody.
Substrate : pNPP
|
文献引用
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产品评论
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![Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004](/upload/website/prouct_img/small/GTX03004/GTX03004_20210507_ELISA_w_23053123_112.webp "Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004")
![Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004](/upload/website/prouct_img/normal/GTX03004/GTX03004_20210507_ELISA_w_23053123_112.webp "Anti-TGF beta 1 antibody [MT593] used in ELISA (ELISA). GTX03004")
