产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
Observed MW
~70 kDa. The observed M.W. is based on the following publication. PMID: 12370298
产品属性
形式
Liquid
存储溶液
PBS, 0.05% BSA, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, we recommend adding 50% glycerol, then aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.48 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
A synthesized peptide derived from human TNF Receptor II
纯化方式
Purified by antigen-affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
TNF receptor superfamily member 1B , CD120b , TBPII , TNF-R-II , TNF-R75 , TNFBR , TNFR1B , TNFR2 , TNFR80 , p75 , p75TNFR
功能与背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
数据库
研究领域
產品图片
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GTX02834 WB Image
Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with TNF Receptor II antibody [GT1237] (GTX02834) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 12370298
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GTX02834 WB Image
WB analysis of various samples using GTX02834 TNF Receptor II antibody [GT1237]. Dilution : 1:1000 Loading : 25μg
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GTX02834 WB Image
WB analysis of various samples using GTX02834 TNF Receptor II antibody [GT1237]. Dilution : 1:1000 Loading : 25μg
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文献引用
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产品评论
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