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TSG101抗体 [4A10]

Recombinant antibody KO/KD Orthogonal Overexpression
Anti-TSG101 antibody [4A10] used in ELISA (ELISA). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255
Anti-TSG101 antibody [4A10] used in Flow cytometry (FACS). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Anti-TSG101 antibody [4A10] used in IHC (Free Floating) (IHC (Free Floating)). GTX70255

目录号 GTX70255

文献引用 203
1

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 4A10

同种型

 IgG1

实验应用

 WB, ICC/IF, IHC-P, FACS, IP, ELISA, EM, IHC, IHC (Free Floating)

种属反应

 Human, Mouse, Rat, Zebrafish, Dog, Hamster, Pig, Monkey
产品包装
100 μl (¥4300)
查看所有 TSG101 的产品
产品说明

摘要

TSG101 antibody [4A10] is a well-validated and highly cited mouse monoclonal antibody that detects TSG101, a protein of 390 amino acids and a predicted molecular weight of 44 kDa that is a core constituent of the ESCRT-I complex. Reports have described it having both tumor suppressor and tumor enhancer activities. TSG101 is involved in exosome secretion and is commonly used as an exosome marker.

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:500-1:1000
IHC-P 1:100-1:1000
FACS 1:25-1:200
IP Assay dependent
ELISA Assay dependent
EM Assay dependent
IHC 1:100
IHC (Free Floating) Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

44 kDa. ( Note )

阳性对照

293T , K562 , THP-1 , HL-60 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , NIH-3T3 , JC , BCL-1

产品说明

Knockdown/Knockout validation was supported by references (PMID:27226592)

产品属性

形式

Liquid

存储溶液

PBS

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1.8 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Amino acids 167-374 of TSG101 protein expressed in E. coli.

纯化方式

Purified by antigen-affinity chromatography.
From tissue culture supernatant

偶联

Unconjugated

RRID

AB_373239

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

tumor susceptibility 101 , TSG10 , VPS23

细胞定位

Cytoplasm , Nucleus

功能与背景

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

数据库

研究领域

產品图片

Anti-TSG101 antibody [4A10] used in ELISA (ELISA). GTX70255

GTX70255 ELISA Image

ELISA detection of TSG101 using GTX118736 for capture at a concentration of 5 μg/mL and GTX70255 for detection at a concentration of 1.5 μg/mL.

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] (GTX70255) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255

GTX70255 IHC-P Image

TSG101 antibody [4A10] detects TSG101 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded human breast carcinoma.
TSG101 stained by TSG101 antibody [4A10] (GTX70255) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-TSG101 antibody [4A10] used in Flow cytometry (FACS). GTX70255

GTX70255 FACS Image

TSG101 antibody [4A10] (GTX70255) detects TSG101 protein by flow cytometry analysis.
Sample: THP-1 cell.
Black: Unlabelled sample was used as a control.
Red: TSG101 antibody [4A10] (GTX70255) dilution: 1:25.
Acquisition of 20,000 events were collected using a Dylight 488-conjugated secondary antibody for FACS analysis.

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] (GTX70255) diluted at 1:500. The HRP-conjugated anti-mouset IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

TSG101 antibody [4A10] detects TSG101 protein by western blot analysis.
A. 30 μg NIH-3T3 whole cell lysate/extract
B. 30 μg JC whole cell lysate/extract
C. 30 μg BCL-1 whole cell lysate/extract
10% SDS-PAGE
TSG101 antibody [4A10] (GTX70255) dilution: 1:500
The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] (GTX70255) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255

GTX70255 IHC-P Image

TSG101 antibody [4A10] detects TSG101 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded human lung cancer.
TSG101 stained by TSG101 antibody [4A10] (GTX70255) diluted at 1:50.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

KO/KD

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] (GTX70255) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in IHC (Paraffin sections) (IHC-P). GTX70255

GTX70255 IHC-P Image

TSG101 antibody [4A10] detects TSG101 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded human ovarian cancer.
TSG101 stained by TSG101 antibody [4A10] (GTX70255) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] (GTX70255) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the Nat Commun in 2016. PMID: 27882925

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

KO/KD Orthogonal Overexpression

The data was published in the Nat Commun in 2016. PMID: 27882925

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal Sci Rep in 2017.PMID: 28303002

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal J Extracell Vesicles in 2012.PMID: 24009879

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

KO/KD

The data was published in the journal J Cell Sci in 2015.PMID: 26002056

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the 2020 in Eur J Neurosci. PMID: 32939863

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the 2020 in Eur J Neurosci. PMID: 32939863

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the 2021 in Sci Rep. PMID: 34127763

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal J Exp Clin Cancer Res in 2018. PMID: 30290833

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal Sci Rep in 2017. PMID: 28963552

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal PLoS Pathog in 2016. PMID: 27203423

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

KO/KD

The data was published in the journal Virol J in 2008. PMID: 18267010

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2020. PMID: 32230970

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Acta Neuropathol Commun in 2017.PMID: 28851452

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Acta Neuropathol Commun in 2017.PMID: 28851452

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Mol Neurodegener in 2017.PMID: 28835279

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Nat Commun in 2015.PMID: 26103923

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Acta Neuropathol Commun in 2017.PMID: 28851452

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal PLoS Biol in 2013.PMID: 23874151

Anti-TSG101 antibody [4A10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70255

GTX70255 ICC/IF Image

The data was published in the journal Mol Neurodegener in 2017.PMID: 28835279

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal PLoS One in 2017. PMID: 28241021

Anti-TSG101 antibody [4A10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70255

GTX70255 ICC/IF Image

The data was published in the journal PLoS Pathog in 2015. PMID: 25710462

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Front Neurosci in 2019. PMID: 32009885

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal Cell Death Dis in 2018. PMID: 29743530

Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255

GTX70255 WB Image

The data was published in the journal PLoS One in 2018. PMID: 29953492

Anti-TSG101 antibody [4A10] used in IHC (Free Floating) (IHC (Free Floating)). GTX70255

GTX70255 IHC (Free Floating) Image

The data was published in the journal Mol Neurodegener in 2017.PMID: 28835279

文献引用

Application Reference

De Feo A et al. Int J Mol Sci 2024; 25 (3) CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles.
HK Jackson et al. J Extracell Vesicles 2024; 13 (2) : e12412 Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological response
实验应用 : WB
Lokumcu T et al. ACS Nano 2024; 18 (3) : 2500-2519 Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity.
A De Feo et al. Int J Mol Sci 2024; 25 (3) : 1588 CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles
实验应用 : WB
W Tian et al. Commun Biol 2024; 7 (1) : 99 Deep proteomic analysis of obstetric antiphospholipid syndrome by DIA-MS of extracellular vesicle enriched fractions
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TSG101 antibody [4A10] 目录号 GTX70255

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实验应用
Western Blot(WB)
( Average 5 based on 1 users reviews)
Anti-TSG101 antibody [4A10] used in Western Blot (WB). GTX70255
Date : Anonymous submitted on 25-Nov-2019
Score :
Application Tested : WB
Sample Species : Hu, Rat
Sample : HEK293, NRK-52E cells
Amount used : 12.5 μg
Blocking : 0.25 % PVP-40 in TBST, 25°C, 1Hr
Primary Antibody : 1:2000, 4°C, 18Hr
我要评论产品
Application Reference
De Feo A et al. Int J Mol Sci 2024; 25 (3) CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles.
HK Jackson et al. J Extracell Vesicles 2024; 13 (2):e12412 Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological response
实验应用 : WB
Lokumcu T et al. ACS Nano 2024; 18 (3):2500-2519 Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity.
A De Feo et al. Int J Mol Sci 2024; 25 (3):1588 CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles
实验应用 : WB
W Tian et al. Commun Biol 2024; 7 (1):99 Deep proteomic analysis of obstetric antiphospholipid syndrome by DIA-MS of extracellular vesicle enriched fractions
Moccia V et al. Animals (Basel) 2023; 13 (21) Isolation and Characterization of Cetacean Cell-Derived Extracellular Vesicles.
Liu B et al. J Nanobiotechnology 2023; 21 (1):352 Critical contributions of protein cargos to the functions of macrophage-derived extracellular vesicles.
Mancarella C et al. Cancer Gene Ther 2023; 30 (9):1285-1295 Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells.
Gargiulo E et al. Blood Cancer Discov 2023; 4 (1):54-77 Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses.
Zauner R et al. Cancers (Basel) 2023; 15 (13) Biomarker Discovery in Rare Malignancies: Development of a miRNA Signature for RDEB-cSCC.
Mansouri-Kivaj N et al. Stem Cell Res Ther 2023; 14 (1):61 Homogenous subpopulation of human mesenchymal stem cells and their extracellular vesicles restore function of endometrium in an experimental rat model of Asherman syndrome.
实验应用 : WB
种属反应 : Human
Zhang C et al. Elife 2023; 12 Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.
实验应用 : WB
种属反应 : Human
Yuan Y et al. Signal Transduct Target Ther 2023; 8 (1):121 Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure.
实验应用 : WB
种属反应 : Mouse
Hsueh YH et al. J Orthop Translat 2023; 38:141-155 Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model.
Deng W et al. Cell Cycle 2022; 21 (16):1775-1783 In vitro experimental study on the formation of microRNA-34a loaded exosomes and their inhibitory effect in oral squamous cell carcinoma.
Martins-Marques T et al. EMBO Rep 2022; 23 (7):e54312 Cx43-mediated sorting of miRNAs into extracellular vesicles.
Lanna A et al. Nat Cell Biol 2022; 24 (10):1461-1474 An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory.
实验应用 : ELISA
种属反应 : Human
McCann J et al. J Extracell Vesicles 2022; 11 (10):e12220 Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA.
实验应用 : WB
种属反应 : Human
Wu B et al. Carcinogenesis 2022; 43 (11):1059-1070 LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma.
实验应用 : WB
种属反应 : Human
Valentina Biagini et al. Int J Mol Sci 2022; 23 (10) Zebrafish Melanoma-Derived Interstitial EVs Are Carriers of ncRNAs That Induce Inflammation.
实验应用 : WB
种属反应 : Zebrafish
Michael Schneider et al. Front Oncol 2022; 12:842418 The Chaperone Protein GRP78 Promotes Survival and Migration of Head and Neck Cancer After Direct Radiation Exposure and Extracellular Vesicle-Transfer.
实验应用 : WB
种属反应 : Human
Jo?o Vasco Ferreira et al. Sci Adv 2022; 8 (12):eabm1140 LAMP2A regulates the loading of proteins into exosomes.
Leary N et al. J Extracell Vesicles 2022; 11 (2):e12197 Melanoma-derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes.
实验应用 : WB
种属反应 : Human
Zhang L et al. J Virol 2022;:jvi0000522 Tumor Susceptibility Gene 101 (TSG101) Contributes to Virion Formation of Porcine Reproductive and Respiratory Syndrome Virus via Interaction with the Nucleocapsid (N) Protein along with the Early Secretory Pathway.
实验应用 : WB
种属反应 : Human
Miserey-Lenkei S et al. Biol Cell 2021; 113 (7):311-328 A comprehensive library of fluorescent constructs of SARS-CoV-2 proteins and their initial characterisation in different cell types.
Federico Gulluni et al. Science 2021; 374 (6573):eabk0410 PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
实验应用 : WB
种属反应 : Human
Yuan-Kun Tu et al. Curr Neurovasc Res 2021; 18 (4):395-408 Human Olfactory Ensheathing Cell-derived Extracellular Cesicles: miRNA Profile and Neuroprotective Effect.
实验应用 : WB
种属反应 : Human
Alessandra Aiello et al. Viruses 2021; 14 (1) HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line.
实验应用 : WB
种属反应 : Human
Sun T et al. Kaohsiung J Med Sci 2021; (Epub) Exosomal microRNA-19b targets FBXW7 to promote colorectal cancer stem cell stemness and induce resistance to radiotherapy.
实验应用 : WB
种属反应 : Human
Hu R et al. Cell Death Discov 2021; 7 (1):262 LncRNA RP11-465B22.8 triggers esophageal cancer progression by targeting miR-765/KLK4 axis.
种属反应 : Human
Volz AK et al. Nat Commun 2021; 12 (1):5671 Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles.
实验应用 : WB
种属反应 : Human
Cone AS et al. Theranostics 2021; 11 (17):8129-8142 Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model.
实验应用 : WB
种属反应 : Human
Song L et al. J Cell Biol 2021; 220 (9) Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1.
实验应用 : WB
种属反应 : Human
Sun L et al. Sci Rep 2021; 11 (1):12477 Multiplex protein profiling method for extracellular vesicle protein detection.
实验应用 : WB
种属反应 : Human
Haghighitalab A et al. Sci Rep 2021; 11 (1):7825 Investigating the effects of IDO1, PTGS2, and TGF-β1 overexpression on immunomodulatory properties of hTERT-MSCs and their extracellular vesicles.
实验应用 : WB
种属反应 : Human
Shen CH et al. Front Cell Dev Biol 2021; 9:642625 ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation.
实验应用 : WB
种属反应 : Human
Hendricks MR et al. Cell Rep 2021; 34 (4):108672 Extracellular vesicles promote transkingdom nutrient transfer during viral-bacterial co-infection.
实验应用 : WB
Inukai R et al. Int J Mol Sci 2021; 22 (3) The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B.
实验应用 : WB
种属反应 : Human
Chhoy P et al. STAR Protoc 2021; 2 (1):100303 Protocol for the separation of extracellular vesicles by ultracentrifugation from in vitro cell culture models.
实验应用 : WB
种属反应 : Human
Logozzi M et al. J Enzyme Inhib Med Chem 2021; 36 (1):175-182 Nanovesicles released by OKT3 hybridoma express fully active antibodies.
实验应用 : WB
种属反应 : Mouse
Liu CC et al. J Virol 2021; 95 (6) The ESCRT-I Subunit Tsg101 Plays Novel Dual Roles in Entry and Replication of Classical Swine Fever Virus.
实验应用 : WB
种属反应 : Pig
Xinhui Liu et al. Front Pharmacol 2020; 11:622658 Involvement of Circulating Exosomal MicroRNAs in Jian-Pi-Yi-Shen Formula Protection Against Adenine-Induced Chronic Kidney Disease.
实验应用 : WB
种属反应 : Rat
Martins-Marques T et al. Life Sci Alliance 2020; 3 (12) Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes.
Chen SD et al. Cells 2020; 9 (8) Circulating MicroRNAs from Serum Exosomes May Serve as a Putative Biomarker in the Diagnosis and Treatment of Patients with Focal Cortical Dysplasia.
Haupt M et al. Stem Cells Transl Med 2020; (Epub) Lithium modulates miR-1906 levels of mesenchymal stem cell-derived extracellular vesicles contributing to poststroke neuroprotection by toll-like receptor 4 regulation.
实验应用 : WB
种属反应 : Mouse
Joshi BS et al. Eur J Neurosci 2020; (Epub) Heparan sulfate proteoglycan-mediated dynamin-dependent transport of neural stem cell exosomes in an in vitro blood-brain barrier model.
实验应用 : WB
种属反应 : Human
Turner DL et al. Elife 2020; 9 The host exosome pathway underpins biogenesis of the human cytomegalovirus virion.
实验应用 : WB
Hasegawa K et al. FEBS J 2020; (Epub) Extracellular vesicles derived from inflamed murine colorectal tissue induce fibroblast proliferation via epidermal growth factor receptor.
实验应用 : WB
种属反应 : Mouse
Mukherjee C et al. Cell Metab 2020; 32 (2):259-272.e10 Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.
实验应用 : WB
Sato M et al. Biochem Biophys Res Commun 2020; 528 (1):199-205 Glucocorticoids negatively regulates chaperone mediated autophagy and microautophagy.
实验应用 : WB
种属反应 : Human
Ou D et al. Cancer Biol Med 2020; 17 (2):328-342 CDK11 negatively regulates Wnt/β-catenin signaling in the endosomal compartment by affecting microtubule stability.
实验应用 : WB
种属反应 : Human
Zheng X et al. Transl Stroke Res 2020; Extracellular Vesicles Derived from Neural Progenitor Cells--a Preclinical Evaluation for Stroke Treatment in Mice.
实验应用 : WB
种属反应 : Mouse
Cone A.S. et al. BMC Molecular and Cell Biology 2020; (Epub) Alix and Syntenin-1 direct amyloid precursor protein and amyloid beta trafficking into extracellular vesicles.
实验应用 : WB
Moertl S et al. Int J Mol Sci 2020; 21 (7) Radiation Exposure of Peripheral Mononuclear Blood Cells Alters the Composition and Function of Secreted Extracellular Vesicles.
实验应用 : WB
种属反应 : Human
Firoozi S et al. Biochem Biophys Res Commun 2020; 524 (4):903-909 Mesenchymal stem cell-derived extracellular vesicles alone or in conjunction with a SDKP-conjugated self-assembling peptide improve a rat model of myocardial infarction.
实验应用 : WB
种属反应 : Human
Tanaka K et al. Biochem Biophys Res Commun 2020; (Epub) Ubiquitination of Src promotes its secretion via small extracellular vesicles.
实验应用 : WB
种属反应 : Dog
Willis CM et al. Neurochem Res 2020; (Epub) The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age.
实验应用 : EM
种属反应 : Mouse
Peng KY et al. Brain 2019; 142 (1):163-175 Apolipoprotein E4 genotype compromises brain exosome production.
Batool A et al. Front Neurosci 2019; 13:1404 Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus.
实验应用 : WB
种属反应 : Mouse
Abed M et al. PLoS One 2019; 14 (4):e0214110 The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.
Quinney KB et al. Proc Natl Acad Sci U S A 2019; 116 (14):6858-6867 Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery.
Temoche-Diaz MM et al. Elife 2019; 8 Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes.
实验应用 : WB
种属反应 : Human
Ajasin DO et al. Elife 2019; 8 CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release.
Logozzi M et al. Cancers (Basel) 2019; 11 (10) Increased Plasmatic Levels of PSA-Expressing Exosomes Distinguish Prostate Cancer Patients from Benign Prostatic Hyperplasia: A Prospective Study.
实验应用 : WB
种属反应 : Human
Jain G et al. Transl Psychiatry 2019; 9 (1):250 A combined miRNA-piRNA signature to detect Alzheimer's disease.
实验应用 : WB
种属反应 : Mouse
Pace KR et al. Int J Mol Sci 2019; 20 (16) Exosomal L1CAM Stimulates Glioblastoma Cell Motility, Proliferation, and Invasiveness.
实验应用 : WB
种属反应 : Human
P?rez-Gonz?lez R et al. Sci Rep 2019; 9 (1):11104 Neuroprotection mediated by cystatin C-loaded extracellular vesicles.
实验应用 : WB
种属反应 : Mouse
Schott MB et al. J Cell Biol 2019; Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes.
种属反应 : Rat
Subedi P et al. Anal Biochem 2019; 584:113390 Comparison of methods to isolate proteins from extracellular vesicles for mass spectrometry-based proteomic analyses.
实验应用 : WB
种属反应 : Human
Tsunemi T et al. J Neurosci 2019; (Epub) Increased lysosomal exocytosis induced by lysosomal Ca2+ channel agonists protects human dopaminergic neurons from 帢-synuclein toxicity.
实验应用 : WB
种属反应 : Human
Inoue J et al. J Virol 2019; (Epub) siRNA Screening for the Small GTPase Rab Proteins Identifies that Rab5B is a Major Regulator of Hepatitis B Virus Production.
实验应用 : WB
种属反应 : Human
Brahmer A et al. J Extracell Vesicles 2019; 8 (1):1615820 Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation.
实验应用 : WB
种属反应 : Human
View ORCID ProfileMorayma M. Temoche-Diaz et al. bioRxiv 2019; (Epub) Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes.
实验应用 : WB
种属反应 : Human
Streetley J et al. Blood 2019; (Epub) Stimulated release of intraluminal vesicles from Weibel-Palade bodies.
种属反应 : Human
Logozzi M et al. Eur J Pharm Biopharm 2019; 137:23-36 Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials.
实验应用 : WB
种属反应 : Human
Logozzi M et al. J Enzyme Inhib Med Chem 2019; 34 (1):272-278 Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity.
实验应用 : WB
种属反应 : Human
Wierz M et al. Methods Mol Biol 2019; 1884:231-245 Purification of Leukemia-Derived Exosomes to Study Microenvironment Modulation.
实验应用 : WB
种属反应 : Human
Noh SH et al. Autophagy 2018; 14 (10):1761-1778 Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR.
Javier Pacheco-Quinto et al. FASEB 2018; (Epub) Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes.
实验应用 : WB
种属反应 : Mouse
Novo D et al. Nat Commun 2018; 9 (1):5069 Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
实验应用 : WB
种属反应 : Human
Li W et al. J Cell Biochem 2018; (Epub) Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.
实验应用 : WB
种属反应 : Human
Boussadia Z et al. J Exp Clin Cancer Res 2018; 37 (1):245 Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules.
实验应用 : WB
种属反应 : Human
Winer H et al. Nat Commun 2018; 9 (1):3744 Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins.
实验应用 : WB
种属反应 : Human
Heisler FF et al. Neuron 2018; 99 (6):1155-1169.e9 Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression.
实验应用 : WB
种属反应 : Mouse
Vincent Hyenne et al. bioRxiv 2018; (Epub) Studying the fate of tumor extracellular vesicles at high spatio-temporal resolution using the zebrafish embryo.
实验应用 : WB
Moriwaki Y et al. PLoS One 2018; 13 (6):e0199829 SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
实验应用 : WB
种属反应 : Mouse
Gao K et al. Cell Death Dis 2018; 9 (5):528 iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.
实验应用 : ICC/IF
种属反应 : Human
Gartner K et al. Cancer Med 2018; (Epub) Tumor-derived extracellular vesicles activate primary monocytes.
实验应用 : WB
种属反应 : Human
Mutschelknaus L et al. Sci Rep 2017; 7 (1):12423 Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Durcin M et al. J Extracell Vesicles 2017; 6 (1):1305677 Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
Lerner N et al. PLoS One 2017; 12 (2):e0171153 Extracellular vesicles mediate signaling between the aqueous humor producing and draining cells in the ocular system.
Jovi?i? A et al. PLoS One 2017; 12 (2):e0171418 Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes.
Guo H et al. Dev Cell 2017; 43 (6):716-730.e7 Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy.
实验应用 : WB
种属反应 : Human
Strickland M et al. Nat Commun 2017; 8 (1):1391 Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
实验应用 : ICC/IF
种属反应 : Human
Koster S et al. Proc Natl Acad Sci U S A 2017; (Epub) Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
实验应用 : WB
种属反应 : Mouse
Gauthier SA et al. Acta Neuropathol Commun 2017; 5 (1):65 Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities.
实验应用 : WB
种属反应 : Human
Willen K et al. Mol Neurodegener 2017; 12 (1):61 Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.
实验应用 : WB, ICC/IF
种属反应 : Mouse
Wills C.M. et al. Front. Neurosci. 2017; (Epub) A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma.
实验应用 : WB, EM
种属反应 : Mouse
Durcin M et al. JEV 2017; (Epub) Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
实验应用 : WB
种属反应 : Mouse
Sun KT et al. Sci Rep 2017; 7 (1):202 Reciprocal regulation of γ-globin expression by exo-miRNAs: Relevance to γ-globin silencing in β-thalassemia major.
实验应用 : WB
种属反应 : Human
Yentrapalli R et al. Int J Radiat Biol 2017;:43112 Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.
Sung BH et al. Cell Adh Migr 2017;:43109 Exosome secretion promotes chemotaxis of cancer cells.
实验应用 : WB
种属反应 : Human
Villarroya-Beltri C et al. Nat Commun 2016; 7:13588 ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins.
Shurtleff MJ et al. Elife 2016; 5 Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction.
实验应用 : WB
种属反应 : Human
Edgar JR et al. Elife 2016; 5 Tetherin is an exosomal tether.
实验应用 : WB
种属反应 : Human
Castelli G et al. Blood Cells Mol Dis 2016; 61:58-65 Conditioned medium from human umbilical vein endothelial cells markedly improves the proliferation and differentiation of circulating endothelial progenitors.
实验应用 : WB
种属反应 : Human
Kamelgarn M et al. Biochim Biophys Acta 2016; 1862 (10):2004-14 Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS.
Sinha S et al. J Cell Biol 2016; 214 (2):197-213 Cortactin promotes exosome secretion by controlling branched actin dynamics.
实验应用 : WB
种属反应 : Human
Cao H et al. J Biol Chem 2016; (Epub) The Endocytic Fate of the Transferrin Receptor is Regulated by c-Abl Kinase.
实验应用 : WB
种属反应 : Human
Park A et al. PLoS Pathog 2016; 12 (5):e1005659 Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway.
实验应用 : WB
种属反应 : Human
Kunadt M et al. Acta Neuropathol 2015; 129 (5):695-713 Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation.
实验应用 : WB
种属反应 : Mouse
Yim YI et al. J Cell Sci 2015; 128 (7):1434-43 The multivesicular body is the major internal site of prion conversion.
实验应用 : WB
种属反应 : Mouse
Edgar JR et al. J Cell Sci 2015; 128 (14):226665 ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation.
实验应用 : WB
种属反应 : Mouse
Fabbri A et al. Toxins (Basel) 2015; 7 (11):4610-21 Cell-to-cell propagation of the bacterial toxin CNF1 via extracellular vesicles: potential impact on the therapeutic use of the toxin.
实验应用 : WB
种属反应 : Human
Zhang M et al. Elife 2015; 4 Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion.
实验应用 : WB
种属反应 : Human
Jang ER et al. J Cell Sci 2015; 128 (23):4428-41 Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
实验应用 : ICC/IF
种属反应 : Human
Kapustin AN et al. Circ Res 2015; 116 (8):1312-23 Vascular smooth muscle cell calcification is mediated by regulated exosome secretion.
实验应用 : WB
种属反应 : Human
Hyenne V et al. J Cell Biol 2015; 211 (1):27-37 RAL-1 controls multivesicular body biogenesis and exosome secretion.
Prescher J et al. PLoS Pathog 2015; 11 (2):e1004677 Super-resolution imaging of ESCRT-proteins at HIV-1 assembly sites.
Tomas A et al. Nat Commun 2015; 6 (Epub):7324 WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway.
实验应用 : ICC/IF
种属反应 : Human
Fruhbeis C et al. J Extracell Vesicles 2015; 4 (Epub):28239 Physical exercise induces * of small extracellular vesicles into the circulation.
实验应用 : WB
种属反应 : Human
Cicero AL et al. Nat Commun 2015; 6 (Epub):7506 Exosomes released by keratinocytes modulate melanocyte pigmentation.
实验应用 : WB
种属反应 : Human
Kirsten Ridder et al. OncoImmunology 2015; Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
实验应用 : WB
种属反应 : Mouse
Kojima K et al. J Biol Chem 2014; 289 (48):33296-310 ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
种属反应 : Human
Traikov S et al. PLoS One 2014; 9 (11):e109372 Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis.
实验应用 : ICC/IF
种属反应 : Human
Calistri A et al. J Cell Physiol 2014; Functional interaction between the ESCRT-I component TSG101 and the HSV-1 tegument ubiquitin specific protease.
实验应用 : IP
种属反应 : Human
Tsunemi T et al. J Neurosci 2014; 34 (46):15281-7 ATP13A2/PARK9 Regulates Secretion of Exosomes and α-Synuclein.
实验应用 : WB
种属反应 : Human
McDonald MK et al. Pain 2014; Functional significance of macrophage-derived exosomes in inflammation and pain.
实验应用 : WB
种属反应 : Mouse
Kolb AR et al. Mol Biol Cell 2014; 25 (2):276-89 ESCRT regulates surface expression of the Kir2.1 potassium channel.
实验应用 : WB
种属反应 : Human
Armstrong A et al. Neuromolecular Med 2014; 16 (1):150-60 Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer's Disease.
实验应用 : WB
种属反应 : Human
Rush JS et al. Mol Cell Endocrinol 2013; 381 (43102):188-97 RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms.
实验应用 : WB
种属反应 : Human
Fruhbeis C et al. PLoS Biol 2013; 11 (7):e1001604 Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication.
Chudak C et al. Retrovirology 2013; 10:140 Identification of late assembly domains of the human endogenous retrovirus-K(HML-2).
实验应用 : WB
种属反应 : Human
New SE et al. Circ Res 2013; 113 (1):26481 Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques.
实验应用 : WB
种属反应 : Mouse
Colombo M et al. J Cell Sci 2013; 126 (Pt 24):5553-65 Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles.
实验应用 : WB
种属反应 : Human
Pietiainen V et al. J Cell Sci 2013; 126 (Pt 17):3961-71 NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation.
实验应用 : WB
种属反应 : Human
Sorrentino V et al. J Lipid Res 2013; 54 (8):2174-84 The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.
实验应用 : WB
种属反应 : Human
Caduco M et al. J Virol 2013; 87 (1):692-6 Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.
实验应用 : WB
种属反应 : Human
Bobrie A et al. J Extracell Vesicles 2012; 1 Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation.
Falguieres T et al. Traffic 2012; 13 (1):131-42 Regulation of the MVB pathway by SCAMP3.
Lee CP et al. PLoS Pathog 2012; 8 (9):e1002904 The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus.
实验应用 : ICC/IF
种属反应 : Human
Choy RW et al. Proc Natl Acad Sci U S A 2012; 109 (30):E2077-82 Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network.
Brankatschk B et al. Sci Signal 2012; 5 (215):ra21 Regulation of the EGF transcriptional response by endocytic sorting.
实验应用 : WB
种属反应 : Human
Nabhan JF et al. Proc Natl Acad Sci U S A 2012; 109 (11):4146-51 Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.
实验应用 : WB
种属反应 : Human
Rush JS et al. J Biol Chem 2012; 287 (1):712-22 Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis.
Tampellini D et al. J Neurosci 2011; 31 (43):15384-90 Impaired β-amyloid secretion in Alzheimer's disease pathogenesis.
实验应用 : ICC/IF
种属反应 : Mouse
Pasqual G et al. PLoS Pathog 2011; 7 (9):e1002232 Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.
实验应用 : WB
种属反应 : Human
Eyster CA et al. Mol Biol Cell 2011; 22 (17):3218-30 MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.
实验应用 : WB
种属反应 : Human
Hahn S et al. J Immunol 2011; 186 (10):5706-18 The PTAP sequence within the p6 domain of human immunodeficiency virus type 1 Gag regulates its ubiquitination and MHC class I antigen presentation.
实验应用 : WB
种属反应 : Human
Apaja PM et al. J Cell Biol 2010; 191 (3):553-70 Quality control for unfolded proteins at the plasma membrane.
实验应用 : WB
种属反应 : Human
Dynek JN et al. EMBO J 2010; 29 (24):4198-209 c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
实验应用 : WB
种属反应 : Human
Balut CM et al. Am J Physiol Cell Physiol 2010; 299 (5):C1015-27 ESCRT-dependent targeting of plasma membrane localized KCa3.1 to the lysosomes.
实验应用 : ICC/IF
种属反应 : Human
Inuzuka T et al. BMC Struct Biol 2010; 10:25 Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition.
实验应用 : WB
种属反应 : Human
Moorman NJ et al. Mol Cell Proteomics 2010; 9 (5):851-60 A targeted spatial-temporal proteomics approach implicates multiple cellular trafficking pathways in human cytomegalovirus virion maturation.
实验应用 : ICC/IF
种属反应 : Human
Leithe E et al. J Cell Sci 2009; 122 (Pt 21):3883-93 Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101.
实验应用 : ICC/IF
种属反应 : Rat
Glozman R et al. J Cell Biol 2009; 184 (6):847-62 N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic.
实验应用 : WB
种属反应 : Human
Chen J et al. Traffic 2009; 10 (10):1488-501 Transferrin-directed internalization and cycling of transferrin receptor 2.
实验应用 : WB
种属反应 : Human
Truschel ST et al. Traffic 2009; 10 (9):1318-36 ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane.
实验应用 : WB
种属反应 : Human
Okumura M et al. Biochem Biophys Res Commun 2009; 386 (1):237-41 Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
实验应用 : WB
Aoh QL et al. Mol Biol Cell 2009; 20 (6):1816-32 SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.
实验应用 : WB
种属反应 : Human
Luyet PP et al. Traffic 2008; 9 (12):2279-90 The ESCRT-I subunit TSG101 controls endosome-to-cytosol release of viral RNA.
实验应用 : WB
种属反应 : Human
Falguieres T et al. Mol Biol Cell 2008; 19 (11):4942-55 In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101.
实验应用 : WB
种属反应 : Hamster
Pons V et al. PLoS Biol 2008; 6 (9):e214 Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.
实验应用 : WB
种属反应 : Human
Valiathan RR et al. Virol J 2008; 5:23 Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag.
实验应用 : WB
种属反应 : Monkey
Shibata H et al. J Biol Chem 2008; 283 (15):9623-32 Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.
实验应用 : WB
种属反应 : Human
Ichioka F et al. FEBS J 2008; 275 (4):682-92 Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4).
实验应用 : WB
种属反应 : Human
Filimonenko M et al. J Cell Biol 2007; 179 (3):485-500 Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.
实验应用 : WB
种属反应 : Human
Audhya A et al. PLoS One 2007; 2 (9):e956 MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation.
实验应用 : WB, ICC/IF
种属反应 : Human
Fraile-Ramos A et al. Cell Microbiol 2007; 9 (12):2955-67 The ESCRT machinery is not required for human cytomegalovirus envelopment.
实验应用 : WB
Kramer-Albers EM et al. Proteomics Clin Appl 2007; 1 (11):1446-61 Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
De Domenico I et al. Mol Biol Cell 2007; 18 (7):2569-78 The molecular mechanism of hepcidin-mediated ferroportin down-regulation.
实验应用 : WB
种属反应 : Human
Tampellini D et al. J Biol Chem 2007; 282 (26):18895-906 Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations.
实验应用 : ICC/IF
种属反应 : Mouse
Langelier C et al. J Virol 2006; 80 (19):9465-80 Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.
实验应用 : ICC/IF
种属反应 : Human
Chertova E et al. J Virol 2006; 80 (18):9039-52 Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages.
实验应用 : WB
种属反应 : Human
Raiborg C et al. J Cell Sci 2006; 119 (Pt 12):2414-24 Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains.
实验应用 : ICC/IF
种属反应 : Human
Razi M et al. Mol Biol Cell 2006; 17 (8):3469-83 Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.
实验应用 : WB
种属反应 : Human
Almeida CG et al. J Neurosci 2006; 26 (16):4277-88 Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.
实验应用 : ICC/IF
种属反应 : Mouse
Duncan LM et al. EMBO J 2006; 25 (8):1635-45 Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.
Bache KG et al. Mol Biol Cell 2006; 17 (6):2513-23 The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.
Hui EK et al. J Virol 2006; 80 (5):2291-308 YRKL sequence of influenza virus * functions as the L domain motif and interacts with VPS28 and Cdc42.
实验应用 : WB
种属反应 : Human
Gullapalli A et al. Mol Biol Cell 2006; 17 (3):1228-38 An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins.
实验应用 : WB
种属反应 : Human
Ward DM et al. J Biol Chem 2005; 280 (11):10548-55 The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells.
实验应用 : WB
种属反应 : Human
Lin Y et al. J Biol Chem 2005; 280 (13):12799-809 Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1.
实验应用 : WB
种属反应 : Human
Irie T et al. J Virol 2005; 79 (20):12617-22 L-domain flanking sequences are important for host interactions and efficient budding of vesicular stomatitis virus recombinants.
实验应用 : WB
Katoh K et al. Biochem J 2005; 391 (Pt 3):677-85 The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B.
Cabezas A et al. J Cell Sci 2005; 118 (Pt 12):2625-35 Alix regulates cortical actin and the spatial distribution of endosomes.
实验应用 : WB
种属反应 : Human
Irie T et al. Virology 2005; 336 (2):291-8 Functional characterization of Ebola virus L-domains using VSV recombinants.
实验应用 : WB
Bache KG et al. Mol Biol Cell 2004; 15 (9):4337-46 The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation.
实验应用 : WB
种属反应 : Human
Stuchell MD et al. J Biol Chem 2004; 279 (34):36059-71 The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.
实验应用 : WB
种属反应 : Human
Sharma M et al. J Cell Biol 2004; 164 (6):923-33 Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes.
实验应用 : WB
Zhu G et al. Int J Cancer 2004; 109 (4):541-7 Reduction of TSG101 protein has a negative impact on tumor cell growth.
实验应用 : WB
种属反应 : Human
Irie T et al. J Virol 2004; 78 (6):2657-65 Budding of PPxY-containing rhabdoviruses is not dependent on host proteins TGS101 and VPS4A.
实验应用 : IP
种属反应 : Human
Heissmeyer V et al. Nat Immunol 2004; 5 (3):255-65 Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.
实验应用 : WB
种属反应 : Mouse
von Schwedler UK et al. Cell 2003; 114 (6):701-13 The protein network of HIV budding.
实验应用 : WB
Strack B et al. Cell 2003; 114 (6):689-99 AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.
实验应用 : WB
种属反应 : Human
Chiou CT et al. J Gen Virol 2003; 84 (Pt 10):2795-805 Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein.
实验应用 : ICC/IF
种属反应 : Hamster
Gottwein E et al. J Virol 2003; 77 (17):9474-85 The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release.
实验应用 : WB
种属反应 : Human
Bache KG et al. J Cell Biol 2003; 162 (3):435-42 Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes.
实验应用 : ICC/IF
种属反应 : Human
Pornillos O et al. J Cell Biol 2003; 162 (3):425-34 HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein.
实验应用 : WB
种属反应 : Human
Zhu G et al. Oncogene 2003; 22 (24):672991 Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer.
实验应用 : IHC
种属反应 : Human
Myers EL et al. J Virol 2002; 76 (22):11226-35 Tsg101, an inactive homologue of ubiquitin ligase e2, interacts specifically with human immunodeficiency virus type 2 gag polyprotein and results in increased levels of ubiquitinated gag.
实验应用 : WB
种属反应 : Human
Bishop N et al. J Cell Biol 2002; 157 (1):91-101 Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates.
实验应用 : WB
种属反应 : Human
Garrus JE et al. Cell 2001; 107 (1):55-65 Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.
实验应用 : WB
种属反应 : Human
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