产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
实验应用 |
稀释倍数 |
1:2000 |
1:100 |
1:50 |
1:100 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS, 1% BSA, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
0.86 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Full length human recombinant protein of human TBXAS1(NP_001052) produced in HEK293T cell.
纯化方式
Purified by affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
thromboxane A synthase 1 , BDPLT14 , CYP5 , CYP5A1 , GHOSAL , THAS , TS , TXAS , TXS
细胞定位
Endoplasmic reticulum membrane
功能与背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
数据库
研究领域
產品图片
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GTX83523 FACS Image
FACS analysis of HEK293T cells transfected with either TXA synthase plasmid(Red) or empty vector control plasmid(Blue) using GTX83523 TXA synthase antibody [2C1].
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GTX83523 IHC-P Image
IHC-P analysis of human liver tissue using GTX83523 TXA synthase antibody [2C1]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min. Dilution : 1:50
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GTX83523 ICC/IF Image
ICC/IF analysis of COS7 cells transiently transfected with TXA synthase plasmid using GTX83523 TXA synthase antibody [2C1].
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GTX83523 FACS Image
FACS analysis of HeLa cells using GTX83523 TXA synthase antibody [2C1]. Red : Primary antibody Blue : Negative control antibody
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GTX83523 FACS Image
FACS analysis of Jurkat cells using GTX83523 TXA synthase antibody [2C1]. Red : Primary antibody Blue : Negative control antibody
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GTX83523 IHC-P Image
IHC-P analysis of human kidney tissue using GTX83523 TXA synthase antibody [2C1]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min. Dilution : 1:50
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GTX83523 WB Image
WB analysis of various cell lines using GTX83523 TXA synthase antibody [2C1]. Loading : 35 ug per lane
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GTX83523 WB Image
WB analysis of HEK293T cells transfected with TXA synthase plasmid (Right) or empty vector (Left) for 48 hrs using GTX83523 TXA synthase antibody [2C1]. Loading : 5 ug per lane
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文献引用
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产品评论
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