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Tau抗体

Anti-Tau antibody used in IHC (Frozen sections) (IHC-Fr). GTX112981
Anti-Tau antibody used in Western Blot (WB). GTX112981
Anti-Tau antibody used in Western Blot (WB). GTX112981
Anti-Tau antibody used in IHC (Paraffin sections) (IHC-P). GTX112981
Anti-Tau antibody used in IHC (Paraffin sections) (IHC-P). GTX112981
Anti-Tau antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX112981

目录号 GTX112981

文献引用 6

宿主

 Rabbit

克隆

 Polyclonal

同种型

 IgG

实验应用

 WB, ICC/IF, IHC-P, IHC-Fr

种属反应

 Human, Mouse, Rat
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 Tau 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IHC-Fr 1:100-1:1000
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

79 kDa. ( Note )

阳性对照

U87-MG , SK-N-SH , IMR32 , SK-N-AS

产品属性

形式

Liquid

存储溶液

PBS, 1% BSA, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.12 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encompassing a sequence within the center region of human Tau. The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_10730753

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU

细胞定位

Cytoplasm , cytosol , Cell membrane; Peripheral membrane protein; Cytoplasmic side , cytoskeleton , Cell projection , axon

功能与背景

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]

数据库

研究领域

產品图片

Anti-Tau antibody used in IHC (Frozen sections) (IHC-Fr). GTX112981

GTX112981 IHC-Fr Image

Tau antibody detects Tau protein expression by immunohistochemical analysis.
Sample: Frozen sectioned E13.5 Rat brain.
Green: Tau protein stained by Tau antibody (GTX112981) diluted at 1:250.
Red: beta Tubulin 3/ TUJ1, a mature neuron marker, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] (GTX631836) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).
Anti-Tau antibody used in Western Blot (WB). GTX112981

GTX112981 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Tau antibody (GTX112981) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Tau antibody used in Western Blot (WB). GTX112981

GTX112981 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Tau antibody (GTX112981) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Tau antibody used in IHC (Paraffin sections) (IHC-P). GTX112981

GTX112981 IHC-P Image

Tau antibody detects Tau protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse eye.
Green: Tau stained by Tau antibody (GTX112981) diluted at 1:500.
Red: beta Tubulin 3/ Tuj1, a cytoskeleton marker, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] (GTX631836) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-Tau antibody used in IHC (Paraffin sections) (IHC-P). GTX112981

GTX112981 IHC-P Image

Tau antibody detects Tau protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse cerebellum.
Tau stained by Tau antibody (GTX112981) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-Tau antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX112981

GTX112981 ICC/IF Image

Tau antibody detects Tau protein by immunofluorescent analysis.
Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Tau stained by Tau antibody (GTX112981) diluted at 1:500.
Red: Tau, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

文献引用

Application Reference

Espinosa-Jim?nez T et al. Cell Biosci 2023; 13 (1) : 52 A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet.
实验应用 : WB
种属反应 : Mouse
Chang YL et al. BMC Biol 2023; 21 (1) : 293 The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
Chen TF et al. Part Fibre Toxicol 2022; 19 (1) : 44 White matter pathology in alzheimer's transgenic mice with chronic exposure to low-level ambient fine particulate matter.
Parul Katiyar et al. Curr Res Toxicol 2022; 3 : 100072 Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells.
实验应用 : WB
种属反应 : Mouse
Sheng-Han Lee et al. PLoS One 2021; 16 (8) : e0254587 Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model.
实验应用 : WB
种属反应 : Mouse
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PBS.pdf
Glycerol.pdf
Thimerosal.pdf
产品包装 报价 (¥)
¥ 4000
¥ 1700
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